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4Ethics of non-therapeutic research on imminently dying patients in the intensive care unitJournal of Medical Ethics 49 (5): 311-318. 2023.Non-therapeutic research with imminently dying patients in intensive care presents complex ethical issues. The vulnerabilities of the imminently dying, together with societal disquiet around death and dying, contribute to an intuition that such research is beyond the legitimate scope of scientific inquiry. Yet excluding imminently dying patients from research hinders the advancement of medical science to the detriment of future patients. Building on existing ethical guidelines for research, we p…Read more
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COVID-19 human challenge trials and randomized controlled trials: lessons for the next pandemicResearch Ethics. forthcoming.The COVID-19 pandemic touched off an unprecedented search for vaccines and treatments. Without question, the development of vaccines to prevent COVID-19 was an enormous scientific accomplishment. Further, the RECOVERY and Solidarity trials identified effective treatments for COVID-19. But all was not success. The urgent need for COVID-19 prevention and treatment fueled an embrace of risks—to research participants and to the reliability of the science itself—as allegedly necessary costs to speed …Read more
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Stepped-wedge trials should be classified as research for the purpose of ethical reviewClinical Trials 16 (6): 580-588. 2019.
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Beyond consent : The trust-based obligations of physicians to patients in clinical researchIn Oonagh Corrigan (ed.), The Limits of Consent: A Socio-Ethical Approach to Human Subject Research in Medicine, Oxford University Press. 2008.
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Who is the research subject in cluster randomized trials in health research?Trials 1 (12): 118. 2011.
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Accommodating quality and service improvement research within existing ethical principlesTrials 19 (1): 334. 2018.Quality and service improvement (QSI) research employs a broad range of methods to enhance the efficiency of healthcare delivery. QSI research differs from traditional healthcare research and poses unique ethical questions. Since QSI research aims to generate knowledge to enhance quality improvement efforts, should it be considered research for regulatory purposes? Is review by a research ethics committee required? Should healthcare providers be considered research participants? If participation…Read more
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When is informed consent required in cluster randomized trials in health research?Trials 1 (12): 202. 2011.
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University of Western OntarioDepartment of Philosophy
Department of Epidemiology and BiostatisticsProfessor -
London, Ontario, Canada
Areas of Specialization
Biomedical Ethics |
Medical Research Ethics |