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12Alienation and Authenticity in Parkinson's Disease and Its TreatmentAmerican Journal of Bioethics Neuroscience 5 (4): 54-56. 2014.Why are some patients with Parkinson's disease unhappy about the outcome of deep brain stimulation (DBS)? Meccaci and Haselager (2014) attempt to answer this question by analyzing the seminal case...
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11Of Meatballs And Invasive Neurotechnological Trials: Additional Considerations for Complex Clinical DecisionsAmerican Journal of Bioethics Neuroscience 9 (2): 100-104. 2018.Using this case, Lavazza and Reichlin (2018) explored the ethical dilemmas associated with decision making in people with Alzheimer’s disease (AD), specifically when their new preferences conflict...
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11Beyond the Right to Injectable HeroinAmerican Journal of Bioethics Neuroscience 1 (1): 48-49. 2010.
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10Situating Empirical Bioethics in Discussions of Post-Trial ResponsibilityAmerican Journal of Bioethics Neuroscience 13 (4): 227-229. 2022.There is a growing recognition that the ongoing use of investigational neural implants requires continued access to clinical expertise and specialized healthcare (e.g., Hendriks et al., 2019). Howe...
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9Changes in Personality Associated with Deep Brain Stimulation: a Qualitative Evaluation of Clinician PerspectivesNeuroethics 14 (1): 109-124. 2019.Gilbert et al. argue that the neuroethics literature discussing the putative effects of Deep Brain Stimulation on personality largely ignores the scientific evidence and presents distorted claims that personality change is induced by the DBS stimulation. This study contributes to the first-hand primary research on the topic exploring DBS clinicians’ views on post-DBS personality change among their patients and its underlying cause. Semi-structured interviews were conducted with sixteen clinician…Read more
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8Avoiding the Premature Introduction of Psychedelic Medicines in Alzheimer’s Disease and Related DisordersAmerican Journal of Bioethics Neuroscience 14 (2): 129-131. 2023.Peterson et al. (2023) identify two potential uses of psychedelic drugs in Alzheimer’s disease and related disorders (AD/ADRD). The first is to treat depression and anxiety that commonly occur afte...
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8Deep Brain Stimulation in Parkinsonian Patients—Implications for Trialing DBS in Intractable Psychiatric DisordersAmerican Journal of Bioethics Neuroscience 2 (1): 14-15. 2011.
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8Justice and Equity in Trials of Deep Brain Stimulation for the Treatment of Addiction and OvereatingAmerican Journal of Bioethics Neuroscience 4 (2): 54-56. 2013.
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7Deep Brain Stimulation and Changes in “Personality”: A Catch-All with Merits and PitfallsAmerican Journal of Bioethics Neuroscience 14 (3): 320-322. 2023.The 30th anniversary of the first DBS surgery of the subthalamic nucleus (STN) for Parkinson’s disease was celebrated in Grenoble this June. Since this initial surgery, the application of DBS has e...
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6Beyond Flourishing: Intersecting Uses and Interests in the Neurotechnology MarketplaceAmerican Journal of Bioethics Neuroscience 10 (4): 178-180. 2019.
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5A principle‐based framework for disclosing a psychosis risk diagnosisBioethics 37 (2): 171-182. 2022.In recent decades, researchers have attempted to prospectively identify individuals at high risk of developing psychosis in the hope of delaying or preventing psychosis onset. These psychosis risk individuals are identified as being in an ‘At-Risk Mental State’ (ARMS) through a standardised psychometric interview. However, disclosure of ARMS status has attracted criticism due to concerns about the risk–benefit ratio of disclosure to patients. Only approximately one quarter of ARMS patients devel…Read more
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Empirical research with Markov regime-switching models often requires the researcher not only to estimate the model but also to test for the presence of more than one regime. Despite the need for both estimation and testing, methods of estimation are better understood than are methods of testing. We bridge this gap by explaining, in detail, how to apply the newest results in the theory of regime testing, developed by Cho and White [Cho, J. S., and H. White 2007. “Testing for Regime Switching.” E…Read more
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