Stanford, California, United States of America
  • © 2015 by the Shock Society.Lung ischemia-reperfusion complicates numerous clinical processes, such as cardiac arrest, transplantation, and major trauma. These conditions generate sterile inflammation, which can cause or worsen acute lung injury. We previously reported that lung and systemic inflammation in a mouse model of ventilated lung IR depends on Toll-like receptor 4 signaling and the presence of alveolar macrophages. Here, we tested the hypothesis that the intestinal microbiome has a rol…Read more