Alejandro Perez

ABSTRACT The objective of this study was to determine the accuracy of a brief informed consent quiz to detect consent comprehension in individuals with cognitive impairment and to explore the degree to which cognitive domains and recent substance use, independently, predict comprehension. We performed a secondary analysis of two cross-sectional studies in individuals with substance use disorders. The ICQ total score was used as the index test and the Montreal Cognitive Assessment as reference standard in receiver operating characteristic curves. Two independent multiple binary logistic regression models were performed using cognitive domains and days of recent substance use as predictors of ICQ outcome. We analyzed data from 215 and 251 participants, respectively. The ICQ showed moderate accuracy for major cognitive impairment and lower accuracy for mild impairment. Optimal cutoff score was set at 10 points or less for detecting comprehension difficulty. Lower scores in Short-Term Memory, Attention, Language, and Orientation increased the probability of failing the ICQ. A procedure including both the ICQ and cognitive screening measure could improve the accuracy of consent comprehension assessments.

Martin Heidegger replanteó la tradicional pregunta “¿qué es el hombre?” a partir de una clave ontológica, es decir, situando la pregunta por el ser en el centro de la problemática filosófica. Se estudiarán, en concreto, las respuestas a esta cuestión realizadas, por un lado, en Ser y tiempo y, por otro lado, en el escrito Meditación (redactado entre 1938/1939). En conjunto, se tratarán de mostrar algunas de las aportaciones relevantes de Heidegger de cara a una redefinición de los seres humanos que está en ciernes en la fase final de la moderni-dad.