B. Chen

Vitalism was long viewed as the most grotesque view in biological theory: appeals to a mysterious life-force, Romantic insistence on the autonomy of life, or worse, a metaphysics of an entirely living universe. In the early twentieth century, attempts were made to present a revised, lighter version that was not weighted down by revisionary metaphysics: “organicism”. And mainstream philosophers of science criticized Driesch and Bergson’s “neovitalism” as a too-strong ontological commitment to the existence of certain entities or “forces”, over and above the system of causal relations studied by mechanistic science, rejecting the weaker form, organicism, as well. But there has been some significant scholarly “push-back” against this orthodox attitude, notably pointing to the 18th-century Montpellier vitalists to show that there are different historical forms of vitalism, including how they relate to mainstream scientific practice. Additionally, some trends in recent biology that run counter to genetic reductionism and the informational model of the gene present themselves as organicist. Here, we examine some cases of vitalism in the twentieth century and today, not just as a historical form but as a significant metaphysical and scientific model. We argue for vitalism’s conceptual originality without either reducing it to mainstream models of science or presenting it as an alternate model of science, by focusing on historical forms of vitalism, logical empiricist critiques thereof and the impact of synthetic biology on current theorizing of vitalism.

The debate on the yan-yi relation was carried out by Chinese philosophers collectively, and the principles and methods in the debate still belong to a living tradition of Chinese philosophy. From Yijing (Book of Changes), Lunyu (Analects), Laozi and Zhuangzi to Wang Bi, "yi" which cannot be expressed fully by yan (language), is not only "idea" or "meaning" in the human mind, but is also some kind of ontological existence, which is beyond yan and emblematic symbols, and unspeakable. Thus, the debate on the yan-yi relation refers firstly to metaphysics, secondly to moral philosophy, and then to epistemology and philosophy of language. Guided by this view, this paper recalls the source of the debate on the yan-yi relation to Yijing and Lunyu, distinguishes four meanings of "yi" in Chinese philosophy, and reconstructs three arguments. These arguments are the "yan cannot express yi fully" argument, "forget yan once you get yi" argument, and "yan can express yi fully" argument. Finally, this paper exposes and comments on those principles, methods and the general tendency shown in the debate from the following five aspects: starting point, value-preference, methodology, texts (papers and books), and influences

Compared with Western Philosophy, Chinese Philosophy seldom talks about "the other world". This difference can be further proved in language categories. What exists in language text is different from what exists in language structure or language categories. Language categories reflect the styles of deep thinking. The lacking of subjunctive in Chinese language reflects the indifference between facts and ultra-facts in Chinese minds. There is a pan-fact attention in Chinese culture, while an ultra-fact attention in Western culture. This difference also embodies in the activities of religion, logic, mathematics and science.

The swarm intelligence algorithm simulates the behavior of animal populations in nature and is a new type of intelligent solution that is different from traditional artificial intelligence. Feature selection is a very common data dimensionality reduction method, which requires us to select the feature subset with the best evaluation criteria from the original feature set. Feature selection, as an effective data processing method, has become a hot research topic in the fields of machine learning, pattern recognition, and data mining and has received extensive attention and attention. In order to verify the improvement effect of the feature selection algorithm based on the swarm intelligence algorithm on the data, this paper conducts experiments on six classes in the city’s first middle school with similar conditions. First, count the current situation of the students in the class, then divide them into classes, use different algorithms to teach them, and count the changes of the students after a period of teaching. The experiment found that the performance of students under the feature selection algorithm is about 30% higher than other teaching methods, and the awareness of cooperation between students reaches 0.8. It solves the contradiction between popularization and improvement and solves the problems of polarization and transformation of underachievers. The individuality of the algorithm has been fully utilized and developed. The test results show that the improved algorithm has faster convergence speed and higher solution accuracy, and the feature selection algorithm based on swarm intelligence algorithm can effectively improve the efficiency of the algorithm.

In biology the term “vitalism” is usually associated with Hans Driesch’s doctrine of the entelechy: entelechies were nonmaterial, bio-specific agents responsible for governing a few peculiar biological phenomena. Since vitalism defined as such violates metaphysical materialism, the received view refutes the doctrine of the entelechy as a metaphysical heresy. But in the early twentieth century, a different, non-metaphysical evaluation of vitalism was endorsed by some biologists and philosophers, which finally led to a logical refutation of the doctrine of the entelechy. In this non-metaphysical evaluation, first, vitalism was not treated as a metaphysical heresy but a legitimate response to the inadequacy of mechanistic explanations in biology. Second, the refutation of vitalism was logically rather than metaphysically supported by contemporary biological knowledge. The entelechy was not a valid concept, because vitalists could neither formulate vital laws, nor offer convincing examples of experimental indeterminism.

ABSTRACTThe six basic emotions have long been considered discrete categories that serve as the primary units of the emotion system. Yet recent evidence indicated underlying connections among them. Here we tested the underlying relationships among the six basic emotions using a perceptual learning procedure. This technique has the potential of causally changing participants’ emotion detection ability. We found that training on detecting a facial expression improved the performance not only on the trained expression but also on other expressions. Such a transfer effect was consistently demonstrated between disgust and anger detection as well as between fear and surprise detection in two experiments. Notably, training on any of the six emotions could improve happiness detection, while sadness detection could only be improved by training on sadness itself, suggesting the uniqueness of happiness and sadness....

Fezf1 and Fezf2 are highly conserved transcription factors that were first identified by their specific expression in the anterior neuroepithelium of Xenopus and zebrafish embryos. These proteins share an N‐terminal domain with homology to the canonical engrailed repressor motif and a C‐terminal DNA binding domain containing six C2H2 zinc‐finger repeats. Over a decade of study indicates that the Fez proteins play critical roles during nervous system development in species as diverse as fruit flies and mice. Herein we discuss recent progress in understanding the functions of Fezf1 and Fezf2 in neurogenesis and cell fate specification during mammalian nervous system development. Going forward we believe that efforts should focus on understanding how expression of these factors is precisely regulated, and on identifying target DNA sequences and interacting partners. Such knowledge may reveal the mechanisms by which Fezf1 and Fezf2 accomplish both independent and redundant functions across diverse tissue and cell types.

This paper focuses on the finite-time synchronization analysis for complex-valued recurrent neural networks with time delays. First, two kinds of common activation functions appearing in the existing references are combined together and more general assumptions are given. To achieve our aim, a nonlinear delayed controller with two independent parameters different from the existing ones is provided, which leads to great difficulty. To overcome it, a newly developed inequality is used. Then, via Lyapunov function approach, some criteria are derived to guarantee the finite-time synchronization of the considered system, and the settling time for synchronization is also estimated. Finally, two numerical simulations are given to support the effectiveness and advantages of the obtained results.

Research increasingly demonstrates that associations between autonomy-relevant parenting and adolescent adjustment generalize across cultures. Yet, there is still an ongoing debate about the role of culture in these effects of autonomy-relevant parenting. The current study aimed to contribute to a more nuanced perspective on this debate by addressing cultural variability in micro-processes involved in autonomy-relevant parenting and, more specifically, in adolescents’ appraisals of and responses to parental behavior. In this vignette-based experimental study, involving 137 South-Korean adolescents (54% female, mean age = 16 years), we examined whether individual differences in vertical collectivism affect the association between descriptions of potentially autonomy-supportive and controlling parenting practices and (a) appraisals of these practices (in terms of perceived autonomy support and control and experiences of autonomy need satisfaction and frustration), and (b) anticipated responses to these practices (i.e., negotiation, submissive compliance, and oppositional defiance). Participants in the autonomy-supportive condition reported more perceived autonomy support and autonomy satisfaction and lower perceived control and autonomy need frustration than participants in the controlling condition. Collectivism moderated between-vignette effects on perceived control and autonomy need frustration such that the differences between the autonomy-supportive and controlling vignettes were less pronounced (yet still significant) among adolescents scoring higher on collectivism. Collectivism did not moderate effects of the vignettes on the responses to parenting, but yielded a main effect, with collectivism relating to more submissive compliance and less oppositional defiance. Overall, the results suggest that both universal and culture-specific processes are involved in autonomy-relevant socialization.

The crude water-soluble oligosaccharides, coded as TOS, VOS and BOS, were isolated from tunica, viscera and whole body of the ascidian Styela clava, which chemical and physical characteristics were determined by several chemical methods, as well as their antioxidant activities by various in vitro assay systems. TOS with the lowest yield had higher sulfate and uronic acid content than the other two samples. The EC50 of TOS, VOS and BOS were 6.32, 3.45 and 5.55 mg/mL against hydroxyl radical and 1.35, 0.77 and 0.90 mg/mL against DPPH radicals, respectively. VOS showed the highest antioxidant activities among three samples. The results indicated that crude oligosaccharide extracted from different parts of Styela clava had antioxidant activities, which could be explored as novel potential antioxidants. © 2011 IEEE.

Starting from Denis Noble’s criticism on the modern synthesis, this article argues that the author’s presentation of the modern synthesis focusses too one-sidedly on the phenomenal characteristics of the living, whereby it is made easily suitable to his criticisms, but risks to remain trapped in a territory-struggle; this criticism lacks an explicit focus on logical matters, and more in particular on the synthetic principles required to situate the relevancy or irrelevancy of phenomenal characteristics beyond territory-struggles. A brief sketch of how the principle of teleology calls for reflexivity allows us to reveal the tension in Noble’s account between, on the one hand, the way in which he stresses the importance of metaphors and language, and, on the other hand, the way in which he invokes empirical arguments to assess the illusory character of certain metaphors.

Recent interest in the external validity of prediction models has produced many methods for finding predictive distributions that are invariant to dataset shifts and can be used for prediction in new, unseen environments. However, these methods consider different types of shifts and have been developed under disparate frameworks, making it difficult to theoretically analyze how solutions differ with respect to stability and accuracy. Taking a causal graphical view, we use a flexible graphical representation to express various types of dataset shifts. Given a known graph of the data generating process, we show that all invariant distributions correspond to a causal hierarchy of graphical operators, which disable the edges in the graph that are responsible for the shifts. The hierarchy provides a common theoretical underpinning for understanding when and how stability to shifts can be achieved, and in what ways stable distributions can differ. We use it to establish conditions for minimax optimal performance across environments, and derive new algorithms that find optimal stable distributions. By using this new perspective, we empirically demonstrate that that there is a tradeoff between minimax and average performance.

A longstanding criticism of Ernest Nagel's model of reduction is that it fails to take theory change into account. This criticism builds on the received view that Nagelian reductions are incompatible with theory change. This article challenges the received view by showing that Nagel's model can easily accommodate theory change. Indeed, Nagel's model is essentially static as it only gives unchanging formal and nonformal conditions for reduction; in contrast, theory change belongs to the dynamic history of science; as a result, the application of Nagel's model to scientific knowledge from different historical periods yields a series of Nagelian reductions of different degrees of reductive success. This Nagelian treatment of theory change is illustrated by considering the enterprise of reducing thermodynamics to statistical mechanics in the late nineteenth century. It is also contended that, in handling theory change Nagel's model has greater merits than subsequent models (exemplified by Kenneth Schaffner's general reduction-replacement model). This article concludes by suggesting that Nagel's model of reduction deals with theory change exactly in the same way as logical empiricism does with historicism.

The recent advances in assisted reproductive technology, such as hormonal stimulation, IVF, and intracytoplasmic sperm injection (ICSI), have made it possible to circumvent many causes of male and female factor infertility. However, uterine infertility is still considered an ‘‘unconditionally infertile’’ condition. Owing to the continued advances in organ transplantation, microvascular anastomosis techniques, and immunosuppressive medicine, the transplantation of organs is no longer restricted to the ones necessary for continued life. Quality-of-life enhancing types of transplantation, such as uterine transplantation, in recent years, have also entered the clinical arena. This undoubtedly brings new hope to such women, but also creates ethical challenges. Selection of the donor, the impact on the recipient and offspring, as well as challenges to moral and social norms are issues that cannot be ignored. In the present review, the ethical issues of transplantation of the uterus will be discussed in light of recent progress in the procedure.