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2© 2015 Nature America, Inc. All rights reserved. The AAA+ ATPase Vps4 disassembles ESCRT-III and is essential for HIV-1 budding and other pathways. Vps4 is a paradigmatic member of a class of hexameric AAA+ ATPases that disassemble protein complexes without degradation. To distinguish between local displacement versus global unfolding mechanisms for complex disassembly, we carried out hydrogen/deuterium exchange during Saccharomyces cerevisiae Vps4 disassembly of a chimeric Vps24-2 ESCRT-III fil…Read more
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1© 2015 Elsevier Ltd and ISBI. All rights reserved. Surgical intervention of second degree burns is often delayed because of the difficulty in visual diagnosis, which increases the risk of scarring and infection. Non-invasive metrics have shown promise in accurately assessing burn depth. Here, we examine the use of spatial frequency domain imaging and laser speckle imaging for predicting burn depth. Contact burn wounds of increasing severity were created on the dorsum of a Yorkshire pig, and woun…Read more
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National Taiwan Normal UniversityResearcher
Taipei, Taiwan
Areas of Interest
Philosophy of Social Science |
Continental Philosophy |