•  20
    A Radical Approach to Ebola: Saving Humans and Other Animals
    with Sarah J. L. Edwards, Charles H. Norell, Phyllis Illari, and Brendan Clarke
    American Journal of Bioethics 18 (10): 35-42. 2018.
    As the usual regulatory framework did not fit well during the last Ebola outbreak, innovative thinking still needed. In the absence of an outbreak, randomised controlled trials of clinical efficacy in humans cannot be done, while during an outbreak such trials will continue to face significant practical, philosophical, and ethical challenges. This article argues that researchers should also test the safety and effectiveness of novel vaccines in wild apes by employing a pluralistic approach to ev…Read more
  •  17
    Gene Doping—in Animals? Ethical Issues at the Intersection of Animal Use, Gene Editing, and Sports Ethics
    with Brendan Parent
    Cambridge Quarterly of Healthcare Ethics 28 (1): 26-39. 2019.
  •  15
    New techniques for the genetic modification of organisms are creating new strategies for addressing persistent public health challenges. For example, the company Oxitec has conducted field trials internationally—and has attempted to conduct field trials in the United States—of a genetically modified mosquito that can be used to control dengue, Zika, and some other mosquito-borne diseases. In 2016, a report commissioned by the National Academies of Sciences, Engineering, and Medicine discussed th…Read more
  •  13
    Ethical issues when modelling brain disorders innon-human primates
    Journal of Medical Ethics 44 (5): 323-327. 2018.
    Non-human animal models of human diseases advance our knowledge of the genetic underpinnings of disease and lead to the development of novel therapies for humans. While mice are the most common model organisms, their usefulness is limited. Larger animals may provide more accurate and valuable disease models, but it has, until recently, been challenging to create large animal disease models. Genome editors, such as Clustered Randomised Interspersed Palindromic Repeat, meet some of these challenge…Read more
  •  7
    Personalized Medicine Is the Postgenomic Condition
    Hastings Center Report 48 (3): 46-47. 2018.
  •  7
    Global bioethics
    Hastings Center Report 47 (6). 2017.
    This August, I participated in the conference “Genome Editing: Biomedical and Ethical Perspectives,” hosted by the Center for the Study of Bioethics at the University of Belgrade and cosponsored by the Division of Medical Ethics of NYU Langone Health and The Hastings Center. The prime minister of Serbia, Ana Brnabić, spoke of the significance of bringing together an international community of bioethicists, acknowledging that ethical, social, and legal issues surrounding gene editing technologies…Read more
  •  5
    Civic Learning for a Democracy in Crisis
    with Bruce Jennings, Michael K. Gusmano, Gregory E. Kaebnick, and Mildred Z. Solomon
    Hastings Center Report 51 (S1): 2-4. 2021.
  •  5
    :In a recent paper in Cambridge Quarterly of Healthcare Ethics on the necessary conditions for morally responsible animal research David DeGrazia and Jeff Sebo claim that the key requirements for morally responsible animal research are an assertion of sufficient net benefit, a worthwhile-life condition, and a no-unnecessary-harm condition. With regards to the assertion of sufficient net benefit, the authors claim that morally responsible research offers unique benefits to humans that outweigh th…Read more
  •  2
    Teens and Research
    Cambridge Quarterly of Healthcare Ethics 25 (4): 659-673. 2016.
  • Experiences at a Federally Qualified Health Center Support Expanded Conception of the Gifts of Precision Medicine
    with Johanna Tayloe Crane
    American Journal of Bioethics 21 (4): 70-72. 2021.
    In “Obligations of the Gift,” Lee argues that ethical thinking regarding return of genetic research results has been too narrowly focused on individual consent and participants’ “right to kn...