•  14
    Spanish psychometric properties of the moral distress scale—revised: a study in healthcare professionals treating COVID-19 patients
    with L. Galiana, C. Moreno-Mulet, A. Carrero-Planells, P. García-Pazo, M. Nadal-Servera, and N. Sansó
    BMC Medical Ethics 24 (1): 1-12. 2023.
    Background Moral distress appears when a healthcare professional is not able to carry out actions in accordance with their professional ethical standards. The Moral Distress Scale-Revised is the most widely used to assess levels of moral distress, but it is not validated in Spanish. The aim of the study is to validate the Spanish version of the Moral Distress Scale – utilised within a sample of Spanish healthcare professionals treating COVID–19 patients. Methods The original (english) and the po…Read more
  •  8
    High resolution structure and double electron-electron resonance of the zebrafish voltage-dependent anion channel 2 reveal an oligomeric population
    with J. Schredelseker, A. Paz, C. Altenbach, C. S. Leung, M. K. Drexler, J. N. Chen, W. L. Hubbell, and J. Abramson
    Background: Biochemical characterization of voltage-dependent anion channel 2 is limited due to an inability to obtain functional protein. Results: The crystal structure ofVDAC2suggests a dimer interface that is confirmed by double electron-electron resonance and cross-linking. Conclusion: zfVDAC2 has a fractional dimeric population. Significance: VDAC isoforms are structurally similar, but this study has identified a number of hot spots that require further exploration. © 2014 by The American S…Read more
  •  7
    Role of Mg 2+ in hammerhead ribozyme catalysis from molecular simulation
    with T. S. Lee, G. M. Giambaşu, M. Martick, W. G. Scott, and D. M. York
    Molecular dynamics simulations have been performed to investigate the role of Mg2+ in the full-length hammerhead ribozyme cleavage reaction. In particular, the aim of this work is to characterize the binding mode and conformational events that give rise to catalytically active conformations and stabilization of the transition state. Toward this end, a series of eight 12 ns molecular dynamics simulations have been performed with different divalent metal binding occupations for the reactant, early…Read more