• Topography of FUS pathology distinguishes late-onset BIBD from aFTLD-U
    with E. B. Lee, J. Russ, L. B. Elman, L. M. Chahine, D. Kremens, B. L. Miller, H. Branch Coslett, J. Q. Trojanowski, V. M. Van Deerlin, and L. F. McCluskey
    Multiple neurodegenerative diseases are characterized by the abnormal accumulation of FUS protein including various subtypes of frontotemporal lobar degeneration with FUS inclusions. These subtypes include atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions, basophilic inclusion body disease and neuronal intermediate filament inclusion disease. Despite considerable overlap, certain pathologic features including differences in inclusion morphology, the subcellular locali…Read more