•  720
    Principles of procreative beneficence (PPBs) hold that parents have good reasons to select the child with the best life prospects. Sparrow (2010) claims that PPBs imply that we should select only female children, unlesswe attach normative significance to “normal” human capacities. We argue that this claim fails on both empirical and logical grounds. Empirically, Sparrow’s argument for greater female wellbeing rests on a selective reading of the evidence and the incorrect assumption that an advan…Read more
  •  560
    A conception of genetic parenthood
    Bioethics 33 (1): 54-59. 2018.
    We seek to develop a plausible conception of genetic parenthood, taking a recent discussion by Heidi Mertes as our point of departure. Mertes considers two conceptions of genetic parenthood—one invoking genetic resemblance, and the other genetic inheritance—and presents counter-examples to both conceptions. We revise Mertes’ second conception so as to avoid these and related counter-examples.
  •  365
    The epistemic costs of compromise in bioethics
    Bioethics 32 (2): 111-118. 2017.
    Bioethicists sometimes defend compromise positions, particularly when they enter debates on applied topics that have traditionally been highly polarised, such as those regarding abortion, euthanasia and embryonic stem cell research. However, defending compromise positions is often regarded with a degree of disdain. Many are intuitively attracted to the view that it is almost always problematic to defend compromise positions, in the sense that we have a significant moral reason not to do so. In t…Read more
  •  171
    We argue in this essay that (1) the embryo is an irredeemably ambiguous entity and its ambiguity casts serious doubt on the arguments claiming its full protection or, at least, its protection against its use as a means fo research, (2) those who claim the embryo should be protected as "one of us" are committed to a position even they do not uphold in their practices, (3) views that defend the protection of the embryo in virtue of its potentiality to become a person fail, and (4) the embryo does…Read more
  •  143
    Lifespan extension and the doctrine of double effect
    with Laura Capitaine and Guido Pennings
    Theoretical Medicine and Bioethics 34 (3): 207-226. 2013.
    Recent developments in biogerontology—the study of the biology of ageing—suggest that it may eventually be possible to intervene in the human ageing process. This, in turn, offers the prospect of significantly postponing the onset of age-related diseases. The biogerontological project, however, has met with strong resistance, especially by deontologists. They consider the act of intervening in the ageing process impermissible on the grounds that it would (most probably) bring about an extended m…Read more
  •  103
    Preimplantation HLA typing: having children to save our loved ones
    Journal of Medical Ethics 31 (10): 582-586. 2005.
    Next SectionPreimplantation tissue typing has been proposed as a method for creating a tissue matched child that can serve as a haematopoietic stem cell donor to save its sick sibling in need of a stem cell transplant. Despite recent promising results, many people have expressed their disapproval of this method. This paper addresses the main concerns of these critics: the risk of preimplantation genetic diagnosis (PGD) for the child to be born; the intention to have a donor child; the limits tha…Read more
  •  98
    In several jurisdictions, sex offenders may be offered chemical castration as an alternative to further incarceration. In some, agreement to chemical castration may be made a formal condition of parole or release. In others, refusal to undergo chemical castration can increase the likelihood of further incarceration though no formal link is made between the two. Offering chemical castration as an alternative to further incarceration is often said to be partially coercive, thus rendering the offen…Read more
  •  96
    Gene editing, identity and benefit
    Philosophical Quarterly 72 (2): 305-325. 2022.
    Some suggest that gene editing human embryos to prevent genetic disorders will be in one respect morally preferable to using genetic selection for the same purpose: gene editing will benefit particular future persons, while genetic selection would merely replace them. We first construct the most plausible defence of this suggestion—the benefit argument—and defend it against a possible objection. We then advance another objection: the benefit argument succeeds only when restricted to cases in whi…Read more
  •  58
    We discuss in this essay the alternative techniques proposed for the isolation of human embryonic stem cells (hESCs) that attempt to satisfy moral issues surrounding killing embryos but show that these techniques are either redundant or do not achieve their intended aim. We discuss the difficulties associated with defining a human embryo and how the lack of clarity on this issue antagonises the ethical debate and impedes hESC research. We present scientific evidence showing that isolation of hES…Read more
  •  56
    Procreative Altruism: Beyond Individualism in Reproductive Selection
    Journal of Medicine and Philosophy 38 (4): 400-419. 2013.
    Existing debate on procreative selection focuses on the well-being of the future child. However, selection decisions can also have significant effects on the well-being of others. Moreover, these effects may run in opposing directions; some traits conducive to the well-being of the selected child may be harmful to others, whereas other traits that limit the child’s well-being may preserve or increase that of others. Prominent selection principles defended to date instruct parents to select a chi…Read more
  •  54
    The Moral Imperative to Conduct Embryonic Stem Cell and Cloning Research
    Cambridge Quarterly of Healthcare Ethics 15 (1): 7-21. 2006.
    On March 8, 2005, the General Assembly adopted the United Nations Declaration on Human Cloning in which Member States are called upon toa) protect adequately human life in the application of life sciencesb) prohibit all forms of human cloning inasmuch as they are incompatible with human dignity and the protection of human lifec) prohibit the application of genetic engineering techniques that may be contrary to human dignityd) prevent the exploitation of women in the application of life sciencese…Read more
  •  54
    U.S. Complicity and Japan's Wartime Medical Atrocities: Time for a Response
    American Journal of Bioethics 15 (6): 40-49. 2015.
    Shortly before and during the Second World War, Japanese doctors and medical researchers conducted large-scale human experiments in occupied China that were at least as gruesome as those conducted by Nazi doctors. Japan never officially acknowledged the occurrence of the experiments, never tried any of the perpetrators, and never provided compensation to the victims or issued an apology. Building on work by Jing-Bao Nie, this article argues that the U.S. government is heavily complicit in this g…Read more
  •  51
    Discussions about the use and derivation of pluripotent human embryonic stem cells are a stumbling block in developing public policy on stem cell research. On the one hand there is a broad consensus on the benefits of these cells for science and biomedicine; on the other hand there is the controversial issue of killing human embryos. I will focus on the compromise position that accepts research on spare embryos, but not on research embryos ('discarded-created-distinction', from now on d-c-d). I …Read more
  •  51
  •  46
    Discussions about the use and derivation of pluripotent human embryonic stem cells are a stumbling block in developing public policy on stem cell research. On the one hand there is a broad consensus on the benefits of these cells for science and biomedicine; on the other hand there is the controversial issue of killing human embryos. I will focus on the compromise position that accepts research on spare embryos, but not on research embryos (‘discarded‐created‐distinction’, from now on d‐c‐d). I …Read more
  •  46
    Creating and sacrificing embryos for stem cells
    Journal of Medical Ethics 31 (6): 366-370. 2005.
    The compromise position that accepts the use and derivation of stem cells from spare in vitro fertilisation embryos but opposes the creation of embryos for these purposes is a very weak ethical position. This paper argues that whatever the basis is on which defenders of this viewpoint accord intrinsic value to the embryo, once they accept the creation and sacrifice of embryos to benefit infertile people with a child-wish, they do not have a sound moral argument to condemn the creation and sacrif…Read more
  •  45
    Advance directives to protect embryos?
    Journal of Medical Ethics 31 (9): 497-498. 2005.
    The continuing debate about the use of human embryonic stem cell researchThere is a growing consensus among scientists worldwide that embryonic stem cell research will lead to the development of therapies for common diseases or conditions that affect millions of people, including neurological disease or injury, diabetes, and myocardial infarction. HES cells are also valuable tools in understanding early human developmental processes, cell division and differentiation mechanisms, drug discovery a…Read more
  •  44
    The majority of embryos created in natural reproduction die spontaneously within a few weeks of conception. Some have argued that, therefore, if one believes the embryo is a person (in the normative sense) one should find ‘natural’ reproduction morally problematic. An extension of this argument holds that, if one accepts embryo deaths in natural reproduction, consistency requires that one also accepts embryo deaths that occur in (i) assisted reproduction via in vitro fertilisation (IVF) and (ii)…Read more
  •  41
    Regulating Genome Editing: For an Enlightened Democratic Governance
    Cambridge Quarterly of Healthcare Ethics 28 (1): 76-88. 2019.
    How should we regulate genome editing in the face of persistent substantive disagreement about the moral status of this technology and its applications? In this paper, we aim to contribute to resolving this question. We first present two diametrically opposed possible approaches to the regulation of genome editing. A first approach, which we refer to as “elitist,” is inspired by Joshua Greene’s work in moral psychology. It aims to derive at an abstract theoretical level what preferences people w…Read more
  •  32
    Killing Discarded Embryos and the Nothing‐is‐Lost Principle
    Journal of Applied Philosophy 30 (4): 289-303. 2013.
    A widely held view holds that it is permissible to conduct destructive research on embryos discarded following fertility treatment, but not on embryos especially created for research. One argument in support of this view appeals to the nothing-is-lost principle. It holds that because discarded embryos will die soon in any case, and something good is expected to come out of using them for research, it is presumptively permissible to do so. It is then claimed that no equivalent justification can b…Read more
  •  30
    Genome Editing in Livestock, Complicity, and the Technological Fix Objection
    Journal of Agricultural and Environmental Ethics 34 (3): 1-17. 2021.
    Genome editing in livestock could potentially be used in ways that help resolve some of the most urgent and serious global problems pertaining to livestock, including animal suffering, pollution, antimicrobial resistance, and the spread of infectious disease. But despite this potential, some may object to pursuing it, not because genome editing is wrong in and of itself, but because it is the wrong kind of solution to the problems it addresses: it is merely a ‘technological fix’ to a complex soc…Read more
  •  29
    Intra-Family Gamete Donation: A Solution to Concerns Regarding Gamete Donation in China?
    with Juhong Liao
    Journal of Bioethical Inquiry 13 (3): 431-438. 2016.
    Gamete donation from third parties is controversial in China as it severs blood ties, which are considered of utmost importance in Confucian tradition. In recent years, infertile couples are increasingly demonstrating a preference for the use of gametes donated by family members to conceive children—known as “intra-family gamete donation.” The main advantage of intra-family gamete donation is that it maintains blood ties between children and both parents. To date there is no practice of intra-fa…Read more
  •  29
    Gene Editing, Identity and Benefit
    Philosophical Quarterly 72 (2): 305-325. 2022.
    Some suggest that gene editing human embryos to prevent genetic disorders will be in one respect morally preferable to using genetic selection for the same purpose: gene editing will benefit particular future persons, while genetic selection would merely replace them. We first construct the most plausible defence of this suggestion—the benefit argument—and defend it against a possible objection. We then advance another objection: the benefit argument succeeds only when restricted to cases in whi…Read more
  •  26
  •  22
    Cloning
    Stanford Encyclopedia of Philosophy. 2008.
    Many countries or jurisdictions have legally banned human cloning or are in the process of doing so. In some countries, including France and Singapore, reproductive cloning of humans is a criminal offence. In 2005, the United Nations adopted a ‘Declaration on Human Cloning’, which calls for a universal ban on human cloning. The debate on human reproductive cloning seems to have drawn to a close. However, since reproductive cloning of mammals has become routine in several countries, there is reas…Read more
  •  18
    The Ethics of Embryonic Stem Cell Research
    Oxford University Press. 2015.
    Embryonic stem cell research holds great promise for biomedical research, but involves the destruction of human embryos. Katrien Devolder explores the tension between the view that embryos should never be deliberately harmed, and the view that such research must go forward. She provides an in-depth analysis of major attempts to resolve the problem.
  •  15
    Euthanasia for Detainees in Belgium
    Cambridge Quarterly of Healthcare Ethics 25 (3): 384-394. 2016.
    In 2011, Frank Van Den Bleeken became the first detainee to request euthanasia under Belgium’s Euthanasia Act of 2002. This article investigates whether it would be lawful and morally permissible for a doctor to accede to this request. Though Van Den Bleeken has not been held accountable for the crimes he committed, he has been detained in an ordinary prison, without appropriate psychiatric care, for more than 30 years. It is first established that VDB’s euthanasia request plausibly meets the re…Read more
  •  14
    What's in a name? Embryos, entities, and ANTities in the stem cell debate
    Journal of Medical Ethics 32 (1): 43-48. 2006.
    This paper discusses two proposals to the US President’s Council on Bioethics that try to overcome the issue of killing embryos in embryonic stem cell research and argues that neither of them can hold good as a compromise solution. The author argues that the groups of people for which the compromises are intended neither need nor want the two compromises, the US government and other governments of countries with restrictive regulation on ES cell research have not provided a clear and sound justi…Read more
  •  13
    Palliative Farming
    The Journal of Ethics 26 (4): 543-561. 2022.
    Billions of animals live and die under deplorable conditions in factory farms. Despite significant efforts to reduce human consumption of animal products and to encourage more humane farming practices, the number of factory-farmed animals is nevertheless on an upward trajectory. In this paper, we suggest that the high levels of suffering combined with short life-expectancies make the situation of many factory-farmed animals relevantly similar to that of palliative patients. Building on this, we …Read more