•  4
    Altered structural brain connectome in young adult fragile X premutation carriers
    with A. Leow, D. Harvey, N. J. Goodrich-Hunsaker, J. Gadelkarim, A. Kumar, S. M. Rivera, and T. J. Simon
    Fragile X premutation carriers are characterized by 55-200 CGG trinucleotide repeats in the 5' untranslated region on the Xq27.3 site of the X chromosome. Clinically, they are associated with the fragile X-Associated Tremor/Ataxia Syndrome, a late-onset neurodegenerative disorder with diffuse white matter neuropathology. Here, we conducted first-ever graph theoretical network analyses in fXPCs using 30-direction diffusion-weighted magnetic resonance images acquired from 42 healthy controls aged …Read more