• SLC transporters as therapeutic targets: emerging opportunities
    with S. W. Yee, R. B. Kim, and K. M. Giacomini
    © 2015 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. Solute carrier transporters — a family of more than 300 membrane-bound proteins that facilitate the transport of a wide array of substrates across biological membranes — have important roles in physiological processes ranging from the cellular uptake of nutrients to the absorption of drugs and other xenobiotics. Several classes of marketed drugs target well-known SLC transporters, such as neurotransm…Read more