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    Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods
    with L. L. Leach, R. H. Croze, V. P. Nadar, T. N. Clevenger, B. O. Pennington, D. M. Gamm, and D. O. Clegg
  •  2
    ROCK inhibition extends passage of pluripotent stem cell-derived retinal pigmented epithelium
    with R. H. Croze, M. J. de BuchholzRadeke, W. J. Thi, P. J. Coffey, and D. O. Clegg
    Human embryonic stem cells offer a potentially unlimited supply of cells for emerging cell-based therapies. Unfortunately, the process of deriving distinct cell types can be time consuming and expensive. In the developed world, age-related macular degeneration is the leading cause of blindness in the elderly, with more than 7.2 million people afflicted in the U.S. alone. Both hESC-derived retinal pigmented epithelium and induced pluripotent stem cell-derived RPE are being developed for AMD thera…Read more