Gainesville, Florida, United States of America
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    Unexpected role for adaptive αβTh17 cells in acute respiratory distress syndrome
    with J. T. Li, A. C. Melton, G. Su, M. de HammLa Femina, J. Howard, X. Fang, S. Bhat, K. M. Huynh, C. M. O'Kane, R. R. Muir, D. F. McAuley, M. A. Matthay, and D. Sheppard
    © 2015 by The American Association of Immunologists, Inc. Acute respiratory distress syndrome is a devastating disorder characterized by increased alveolar permeability with no effective treatment beyond supportive care. Current mechanisms underlying ARDS focus on alveolar endothelial and epithelial injury caused by products of innate immune cells and platelets. However, the role of adaptive immune cells in ARDS remains largely unknown. In this study, we report that expansion of Ag-specific abTh…Read more