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    Trazodone effects on obstructive sleep apnea and non-REM arousal threshold
    with E. T. Smales, B. A. Edwards, P. N. Deyoung, D. G. McSharry, A. Wellman, A. Velasquez, J. E. Orr, and A. Malhotra
    Copyright © 2015 by the American Thoracic Society. Rationale: A low respiratory arousal threshold is a physiological trait involved in obstructive sleep apnea pathogenesis. Trazodone may increase arousal threshold without compromising upper airway muscles, which should improve OSA. Objectives: We aimed to examine how trazodone alters OSA severity and arousal threshold. We hypothesized that trazodone would increase the arousal threshold and improve the apnea/hypopnea index in selected patients wi…Read more