• Spinal myxopapillary ependymomas demonstrate a warburg phenotype
    with S. Agnihotri, K. C. Bertrand, X. Wang, D. J. Shih, H. Witt, N. Hill, K. Zayne, M. Barszczyk, V. Ramaswamy, M. Remke, Y. Thompson, M. Ryzhova, L. Massimi, W. Grajkowska, B. Lach, N. Gupta, W. A. Weiss, A. Guha, C. Hawkins, S. Croul, J. T. Rutka, S. M. Pfister, A. Korshunov, M. Pekmezci, T. Tihan, J. J. Philips, N. Jabado, G. Zadeh, and M. D. Taylor
    © 2015 American Association for Cancer Research.Purpose: Myxopapillary ependymoma is a distinct histologic variant of ependymoma arising commonly in the spinal cord. Despite an overall favorable prognosis, distant metastases, subarachnoid dissemination, and late recurrences have been reported. Currently, the only effective treatment for MPE is gross-total resection. We characterized the genomic and transcriptional landscape of spinal ependymomas in an effort to delineate the genetic basis of thi…Read more