•  16
    Tseng, Roy, Confucian Liberalism: Mou Zongsan and Hegelian Liberalism
    Dao: A Journal of Comparative Philosophy 22 (4): 685-691. 2023.
  •  6
    Understanding cell biology of three-dimensional biological structures is important for more complete appreciation of in vivo tissue function and advancing ex vivo organ engineering efforts. To elucidate how 3D structure may affect hepatocyte cellular responses, we compared global gene expression of human liver hepatocellular carcinoma cell line cells cultured as monolayers on tissue culture dishes or as spheroids within rotating wall vessel bioreactors. HepG2 cells grown in RWVs form spheroids u…Read more
  •  5
    Geriatric trauma is an important challenge facing trauma surgeons and trauma systems. This problem will assume increasing importance over the next several decades as the population of the United States ages. Training programs should prepare the next generation of surgeons to recognize the unique patterns of injury and meet the physiologic, rehabilitation, and ethical challenges of injury to senior citizens. © 2006 Elsevier Inc. All rights reserved.
  •  3
    Recovery from EAE is associated with decreased survival of encephalitogenic T cells in the CNS of B7-1/B7-2-deficient mice (review)
    with R. A. Sobel, T. Wei, R. M. Ransohoff, V. K. Kuchroo, and A. H. Sharpe
    Adoptive transfer experiments using C57BL/6 mice lacking B7-1 and B7-2 as recipients of wt encephalitogenic T cells demonstrate a key role for B7 costimulation during the effector phase of experimental autoimmune encephalomyelitis. Following transfer of encephalitogenic T cells, B7-1/B7-2-deficient recipients develop a transient and mild disease as compared to wt recipients. To understand the mechanism by which B7-1/B7-2 may influence the effector phase of EAE, we analyzed T cells, pro-inflammat…Read more
  •  2
    Genetic background determines the requirement for B7 costimulation in induction of autoimmunity
    with C. Jabs, B. Greve, R. A. Sobel, A. H. Sharpe, and V. K. Kuchroo
    B7 costimulatory molecules play an important role in inducing autoimmunity, tumor immunity, and transplant rejection, and therapeutic manipulation of B7 is being investigated in human diseases. To determine whether B7 costimulation is essential for inducing autoimmunity on different genetic backgrounds, we backcrossed B7.1/B7.2 deficient ) mice on to the C57BL/6 and SJL backgrounds and induced experimental autoimmune encephalomyelitis in these mice. B7.1/B7.2 mice on the B6 background were resis…Read more