•  5
    Charge density wave transition in single-layer titanium diselenide
    with P. Chen, Y. H. Chan, Y. Zhang, M. Y. Chou, S. K. Mo, Z. Hussain, A. V. Fedorov, and T. C. Chiang
    © 2015 Macmillan Publishers Limited. All rights reserved.A single molecular layer of titanium diselenide is a promising material for advanced electronics beyond graphene - a strong focus of current research. Such molecular layers are at the quantum limit of device miniaturization and can show enhanced electronic effects not realizable in thick films. We show that single-layer TiSe2 exhibits a charge density wave transition at critical temperature TC =232±5 K, which is higher than the bulk TC =20…Read more
  •  3
    Unexpected role for adaptive αβTh17 cells in acute respiratory distress syndrome
    with J. T. Li, A. C. Melton, G. Su, M. de HammLa Femina, J. Howard, S. Bhat, K. M. Huynh, C. M. O'Kane, R. J. Ingram, R. R. Muir, D. F. McAuley, M. A. Matthay, and D. Sheppard
    © 2015 by The American Association of Immunologists, Inc. Acute respiratory distress syndrome is a devastating disorder characterized by increased alveolar permeability with no effective treatment beyond supportive care. Current mechanisms underlying ARDS focus on alveolar endothelial and epithelial injury caused by products of innate immune cells and platelets. However, the role of adaptive immune cells in ARDS remains largely unknown. In this study, we report that expansion of Ag-specific abTh…Read more
  •  2
    Mesenchymal stem cells for treatment of ARDS: a phase 1 clinical trial
    with J. G. Wilson, K. D. Liu, N. Zhuo, L. Caballero, M. McMillan, K. Cosgrove, R. Vojnik, C. S. Calfee, Lee J. -W., A. J. Rogers, J. Levitt, J. Wiener-Kronish, E. K. Bajwa, A. Leavitt, D. McKenna, B. T. Thompson, and M. A. Matthay
  •  2
    Design and implementation of the START trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome (review)
    with K. D. Liu, J. G. Wilson, H. Zhuo, L. Caballero, M. L. McMillan, K. Cosgrove, C. S. Calfee, J. W. Lee, K. N. Kangelaris, J. E. Gotts, A. J. Rogers, J. E. Levitt, J. P. Wiener-Kronish, K. L. Delucchi, A. D. Leavitt, D. H. McKenna, B. T. Thompson, and M. A. Matthay
    Background Despite advances in supportive care, moderate-severe acute respiratory distress syndrome is associated with high mortality rates, and novel therapies to treat this condition are needed. Compelling pre-clinical data from mouse, rat, sheep and ex vivo perfused human lung models support the use of human mesenchymal stem cells as a novel intravenous therapy for the early treatment of ARDS. Methods This article describes the study design and challenges encountered during the implementation…Read more
  •  2
    Human mesenchymal stem cells promote the resolution of acute lung injury in part through lipoxin A4
    with J. Abbott, L. Cheng, J. K. Colby, J. W. Lee, B. D. Levy, and M. A. Matthay
    Copyright © 2015 by The American Association of Immunologists, Inc. Previous studies demonstrated that bone marrow-derived mesenchymal stem cells reduce the severity of acute lung injury in animal models and in an ex vivo perfused human lung model. However, the mechanisms by which MSCs reduce lung injury are not well understood. In the present study, we tested the hypothesis that human MSCs promote the resolution of acute lung injury in part through the effects of a specialized proresolving medi…Read more
  •  2
    Dimensional Effects on the Charge Density Waves in Ultrathin Films of TiSe 2
    with P. Chen, Y. H. Chan, M. H. Wong, M. Y. Chou, S. K. Mo, Z. Hussain, A. V. Fedorov, and T. C. Chiang
    © 2016 American Chemical Society.Charge density wave formation in solids is a critical phenomenon involving the collective reorganization of the electrons and atoms in the system into a wave structure, and it is expected to be sensitive to the geometric constraint of the system at the nanoscale. Here, we study the CDW transition in TiSe2, a quasi-two-dimensional layered material, to determine the effects of quantum confinement and changing dimensions in films ranging from a single layer to multi…Read more
  • Hidden Order and Dimensional Crossover of the Charge Density Waves in TiSe 2
    with P. Chen, Y. H. Chan, S. K. Mo, Z. Hussain, A. V. Fedorov, M. Y. Chou, and T. C. Chiang
    © The Author 2016.Charge density wave formation, a key physics issue for materials, arises from interactions among electrons and phonons that can also lead to superconductivity and other competing or entangled phases. The prototypical system TiSe 2, with a particularly simple transition and no Kohn anomalies caused by electron-phonon coupling, is a fascinating but unsolved case after decades of research. Our angle-resolved photoemission measurements of the band structure as a function of tempera…Read more