Xue Zhu

Jian Zhou,* Weiqiang Ju,* Xiaopeng Yuan, Xiaofeng Zhu, Dongping Wang, Xiaoshun HeOrgan Transplant Center, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China *These authors contributed equally to this work: Hyperosmolar nonketotic hyperglycemic coma is a serious, rare complication induced by methylprednisolone pulse therapy for acute rejection after orthotopic liver transplantation. Herein, we report an unusual case of a 58-year-old woman who experienced acute rejection at 30 months after OLT, only one case in which HNKHC resulted in MP pulse therapy for acute rejection in all 913 recipients in our center. The general morbidity of HNKHC was 1.09‰ in this study. HNKHC is characterized by rapid onset, rapid progression, and a lack of specific clinical manifestations. High-dose MP management was a clear risk factor. The principle of treatment included rapid rehydration, low-dose insulin infusion, and correcting disorders of electrolytes and acidosis. In conclusion, clinicians considering MP pulse therapy after OLT should be alert to the occurrence of HNKHC. Keywords: liver transplantation, complications, hyperosmolar nonketotic hyperglycemic coma, methylprednisolone pulse therapy, principle of treatment.

A Sr2Cu2Oy sample was prepared and the obtained Tc and Tc were 109 K and 51 K, respectively. A comparison of the M2+ ionic radius, lattice constants a and c, and the interatomic distance sum of the Cu-O and -O samples in the Sr2Cu2Oy system was made, where M = Sr, Ca, Mg, Hg, Cd or Cu. It was found that if the atomic radius of M2+, which is in the -O plane of the -1212 specimen, is larger, then the sample will have a higher Tc and the major effect of the M2+ on the Tc of Sr2Cu2Oy samples was to change the interatomic distance sum of Cu-O and -O when the Cu2+ ion was exchanged for an M2+ ion