Yang Lu

BackgroundDepression and anxiety create a large health burden and increase the risk of premature mortality. Mental health screening is vital, but more sophisticated screening and monitoring methods are needed. The Ellipsis Health App addresses this need by using semantic information from recorded speech to screen for depression and anxiety.ObjectivesThe primary aim of this study is to determine the feasibility of collecting weekly voice samples for mental health screening. Additionally, we aim to demonstrate portability and improved performance of Ellipsis’ machine learning models for patients of various ages.MethodsStudy participants were current patients at Desert Oasis Healthcare, mean age 63 years. Two non-randomized cohorts participated: one with a documented history of depression within 24 months prior to the study, and the other without depression. Participants recorded 5-min voice samples weekly for 6 weeks via the Ellipsis Health App. They also completed PHQ-8 and GAD-7 questionnaires to assess for depression and anxiety, respectively.ResultsProtocol completion rate was 61% for both groups. Use beyond protocol was 27% for Group Positive and 9% for Group Negative. The Ellipsis Health App showed an AUC of 0.82 for the combined groups when compared to the PHQ-8 and GAD-7 with a threshold score of 10. Performance was high for senior participants as well as younger age ranges. Additionally, many participants spoke longer than the required 5 min.ConclusionThe Ellipsis Health App demonstrated feasibility in using voice recordings to screen for depression and anxiety among various age groups and the machine learning models using Transformer methodology maintain performance and improve over LSTM methodology when applied to the study population.

Aristotle's idea of music education in its aesthetics a pivotal part, but have traditionally not been given due attention. Aristotle, as the music for the need to cultivate character and sentiment, the pleasure that it can resonate in the soul of the character, and harmony of music, not only the harmony of the soul directly, and ultimately by the number of principles, reflecting the harmony of the universe. To a certain extent, Aristotle's idea to show how music education in the ancient art of living in the musical supremacy. Aristotle's thought on music education is an essential in his aesthetic theories, yet in a large degree neglected by academic attentions. Aristotle maintains that music should be studied not for the sake of one, but of many benefits, with a view of education, purgation and . enjoyment. Seeing musical pleasure harmonized the soul's character, like Plato did, Aristotle takes harmony of universe the final cause of the beauty of music. Both Plato and Aristotle's thought on music may explain why music always holds a unique place among ancient cultures