Barry Smith

University at Buffalo
National Center for Ontological Research
  • University at Buffalo
    Department of Philosophy
    Biomedical Informatics
    Neurology
    Computer Science and Engineering
    Distinguished Professor, Julian Park Chair
  • National Center for Ontological Research
    Administrator
  • Università della Svizzera Italiana
    Institute of Philosophy (ISFI)
    Visiting Professor (Part-time)
University of Manchester
Department of Philosophy
PhD, 1976
APA Eastern Division
CV
Buffalo, New York, United States of America
  •  298
    Relations in Biomedical Ontologies
    with Werner Ceusters, Bert Klagges, Jacob Köhler, Anand Kuma, Jane Lomax, Chris Mungall, ,, Fabian Neuhaus, Alan Rector, and Cornelius Rosse
    Genome Biology 6 (5). 2005.
    To enhance the treatment of relations in biomedical ontologies we advance a methodology for providing consistent and unambiguous formal definitions of the relational expressions used in such ontologies in a way designed to assist developers and users in avoiding errors in coding and annotation. The resulting Relation Ontology can promote interoperability of ontologies and support new types of automated reasoning about the spatial and temporal dimensions of biological and medical phenomena.
  •  1027
    For much of the first fifty years of its existence, analytic philosophy shunned discussions of normativity and ethics. Ethical statements were considered as pseudo-propositions, or as expressions of pro- or con-attitudes of minor theoretical significance. Nowadays, in contrast, prominent analytic philosophers pay close attention to normative problems. Here we focus our attention on the work of Searle, at the same time drawing out an important connection between Searle’s work and that of two othe…Read more
  •  316
    Concept systems and ontologies: Recommendations for basic terminology
    with Gunnar O. Klein
    Transactions of the Japanese Society for Artificial Intelligence 25 (3): 433-441. 2010.
    This is the third draft of a paper that aims to clarify the apparent contradictions in the views presented in certain standards and other specifications of health informatics systems, contradictions which come to light when the latter are evaluated from the perspective of realist philosophy. One of the origins of this document was Klein’s discussion paper of 2005-07-02 entitled “Conceptology vs Reality” and the responses from Smith, as well as the several hours of discussions during the 2005 …Read more
  •  393
    Foundations for a Realist Ontology of Mental Disease
    with Werner Ceusters
    Journal of Biomedical Semantics 1 (10): 1-23. 2010.
    While classifications of mental disorders have existed for over one hundred years, it still remains unspecified what terms such as 'mental disorder', 'disease' and 'illness' might actually denote. While ontologies have been called in aid to address this shortfall since the GALEN project of the early 1990s, most attempts thus far have sought to provide a formal description of the structure of some pre-existing terminology or classification, rather than of the corresponding structures and processe…Read more
  •  258
    Vérifacteurs
    Etudes de Philosophie 9 104-138. 2008-2011.
    French translation of "Truth-Makers" (1984). A realist theory of truth for a class of sentence holds that there are entities in virtue of which these sentences are true or false. We call such entities ‘truthmakers’ and contend that those for a wide range of sentences about the real world are moments (dependent particulars). Since moments are unfamiliar we provide a definition and a brief philosophical history, anchoring them in our ontology by showing that they are objects of perception. The co…Read more
  •  449
    Kraus on Weininger, Kraus on Women, Kraus on Serbia
    In Wolfgang Huemer & Marc-Oliver Schuster (eds.), Writing the Austrian Traditions: Relations Between Philosophy and Literature, University of Alberta Press. pp. 81-100. 2003.
    Otto Weininger’s Sex and Character interprets Kant’s categorical imperative in a way which takes it to imply that all human relations, including human sexual relations, are immoral; it is thus in a certain sense impossible to lead a moral life on this earth. We discuss Weininger’s ideas on man, woman, value and intellect, and describe their influence among the Central European intellectuals of his day, including Wittgenstein, and also including Karl Kraus.
  •  55
    Surrounding Space
    with Achille C. Varzi
    Theory in Biosciences 121 (2): 139-162. 2002.
    The history of evolution is a history of development from less to more complex organisms. This growth in complexity of organisms goes hand in hand with a concurrent growth in complexity of environments and of organism-environment relations. It is a concern with this latter aspect of evolutionary development that motivates the present paper. We begin by outlining a theory of organism-environment relations. We then show that the theory can be applied to a range of different sorts of cases, both bi…Read more
  •  437
    A strategy for improving and integrating biomedical ontologies
    with Cornelius Rosse, Anand Kumar, Jose L. V. Mejino, Daniel L. Cook, and Landon T. Detwiler
    The integration of biomedical terminologies is indispensable to the process of information integration. When terminologies are linked merely through the alignment of their leaf terms, however, differences in context and ontological structure are ignored. Making use of the SNAP and SPAN ontologies, we show how three reference domain ontologies can be integrated at a higher level, through what we shall call the OBR framework (for: Ontology of Biomedical Reality). OBR is designed to facilitate infe…Read more
  •  24
    Alexius Meinong, On Objects of Higher Order and Husserl's Phenomenology (review)
    Philosophical Quarterly 30 (120): 252. 1980.
  •  564
    A survey of theories of part, whole and dependence from Aristotle to the Gestalt psychologists, with special attention to Husserl’s Third Logical Investigation “On the Theory of Parts and Wholes”.
  •  176
    Wittgensteinian Philosophy and the Culture of the Commentary
    In Rudolf Haller & Johannes Brandl (eds.), Wittgenstein: Towards a Re-Evaluation, Volume 2, Hölder-pichler-tempsky. pp. 247-254. 1990.
    The object of the present paper is the philosophical commentary, a form of literature that once predominated in all major philosophical cultures from classical Greece to Renaissance Italy, but which has more recently fallen into comparative disuse. Commentaries on the writings of German thinkers such as Kant, Hegel, Marx and Heidegger have, certainly, kept the form alive to some extent in recent centuries; in the tradition of philosophy that was initiated by Descartes and Locke, however, and whi…Read more
  •  319
    Medical terminology collects and organizes the many different kinds of terms employed in the biomedical domain both by practitioners and also in the course of biomedical research. In addition to serving as labels for biomedical classes, these names reflect the organizational principles of biomedical vocabularies and ontologies. Some names represent invariant features (classes, universals) of biomedical reality (i.e., they are a matter for ontology). Other names, however, convey also how this rea…Read more
  •  255
    Dieses Buch betritt Neuland. Es ist eine Einführung in das neue Gebiet der angewandten Ontologie, jenem multidisziplinären Arbeitsgebiet, in dem Philosophen gemeinsam mit Informatikern und Vertretern der jeweils thematischen Wissenschaftsbereiche, in unserem Fall mit Biologen und Medizinern, daran arbeiten, wissenschaftliches Wissen informationstechnisch zu repräsentieren. Es zeigt, wie Philosophie eine praktische Anwendung findet, die von zunehmender Wichtigkeit nicht nur in den heutigen Lebens…Read more
  •  615
    In defense of extreme (fallibilistic) apriorism
    Journal of Libertarian Studies 12 (1). 1996.
    We presuppose a position of scientific realism to the effect (i) that the world exists and (ii) that through the working out of ever more sophisticated theories our scientific picture of reality will approximate ever more closely to the world as it really is. Against this background consider, now, the following question: 1. Do the empirical theories with the help of which we seek to approximate a good or true picture of reality rest on any non-empirical presuppositions? One can answer this quest…Read more
  •  653
    The Protein Ontology: A structured representation of protein forms and complexes
    with Darren Natale, Cecilia N. Arighi, Winona C. Barker, Judith A. Blake, Carol J. Bult, Michael Caudy, Harold J. Drabkin, Peter D’Eustachio, Alexei V. Evsikov, Hongzhan Huang, Jules Nchoutmboube, Natalia V. Roberts, Jian Zhang, and Cathy H. Wu
    Nucleic Acids Research 39 (1). 2011.
    The Protein Ontology (PRO) provides a formal, logically-based classification of specific protein classes including structured representations of protein isoforms, variants and modified forms. Initially focused on proteins found in human, mouse and Escherichia coli, PRO now includes representations of protein complexes. The PRO Consortium works in concert with the developers of other biomedical ontologies and protein knowledge bases to provide the ability to formally organize and integrate repres…Read more
  •  425
    Logic and formal ontology
    Manuscrito 23 (2): 275-323. 2000.
    Revised version of chapter in J. N. Mohanty and W. McKenna (eds.), Husserl’s Phenomenology: A Textbook, Lanham: University Press of America, 1989, 29–67. Logic for Husserl is a science of science, a science of what all sciences have in common in their modes of validation. Thus logic deals with universal laws relating to truth, to deduction, to verification and falsification, and with laws relating to theory as such, and to what makes for theoretical unity, both on the side of the propositions of…Read more
  •  348
    On the Austrianness of Austrian economics
    Critical Review: A Journal of Politics and Society 4 (1-2): 212-238. 1990.
    Much recent work on the intellectual background of Austrian economics reveals an unfortunate lack of awareness of the distinct nature of the Austrian contribution to philosophy, from which the Austrian economists drew many of their ideas. The present essay offers a sketch of this contribution, contrasting Austrian philosophy especially with the modes of philosophy dominant in Germany. This makes it possible to throw new light on the relations on Mises, Kant and the Vienna circle, and it allows u…Read more
  •  361
    From the point of view of Brentano’s philosophy, contemporary philosophy of mind presupposes an over-crude theory of the internal structures of mental acts and states and of the corresponding types of parts, unity and dependence. We here describe Brentano’s own account of the part-whole structures obtaining in the mental sphere, and show how it opens up new possibilities for mereological investigation. One feature of Brentano’s view is that the objects of experience are themselves parts of mind,…Read more
  •  332
    Constraints on Correspondence
    In H. Rutte, W. Sauer & W. Gombocz (eds.), Traditionen und Perspektiven der analytischen Philosophie: Festschrift für Rudolf Haller, Hölder/pichler/tempsky. pp. 415-430. 1989.
    My aim is to lay down some constraints on a correspondence theory of truth for empirical sentences of a natural language on the basis of a theory according to which that to which a true empirical sentence of such a language corresponds is a part of the natural world. The problem is to find some means of delineating those portions of the world which serve as correspondents, portions of reality otherwise called ‘truthmakers’.
  •  495
    Assessing Ontologies: The Question of Human Origins and Its Ethical Significance
    In Edmund Runggaldier, Christian Kanzian & Josef Quitterer (eds.), Persons: An Interdisciplinary Approach, Öbvhpt. pp. 243--259. 2003.
    In their paper “Sixteen Days” Barry Smith and Berit Brogaard try to answer the question: when does a human being begin to exist? In this paper we will address some methodological issues connected with this exercise in ontology. We shall begin by sketching the argument of “Sixteen Days”. We shall then attempt to characterize what is special about the ontological realism of “Sixteen Days” as contrasted to the linguistic constructivism which represents the more dominant current in contemporary anal…Read more
  •  295
    Horizontal Integration of Warfighter Intelligence Data: A Shared Semantic Resource for the Intelligence Community
    with Tatiana Malyuta, William S. Mandrick, Chia Fu, Kesny Parent, and Milan Patel
    In Barry Smith, Tatiana Malyuta, William S. Mandrick, Chia Fu, Kesny Parent & Milan Patel (eds.), Proceedings of the Conference on Semantic Technology in Intelligence, Defense and Security (STIDS), CEUR, . pp. 1-8. 2012.
    We describe a strategy that is being used for the horizontal integration of warfighter intelligence data within the framework of the US Army’s Distributed Common Ground System Standard Cloud (DSC) initiative. The strategy rests on the development of a set of ontologies that are being incrementally applied to bring about what we call the ‘semantic enhancement’ of data models used within each intelligence discipline. We show how the strategy can help to overcome familiar tendencies to stovepiping …Read more
  •  273
    Biomedical informatics and granularity
    with Anand Kumar
    Comparative and Functional Genomics 5 (6-7): 501-508. 2004.
    An explicit formal-ontological representation of entities existing at multiple levels of granularity is an urgent requirement for biomedical information processing. We discuss some fundamental principles which can form a basis for such a representation. We also comment on some of the implicit treatments of granularity in currently available ontologies and terminologies (GO, FMA, SNOMED CT).
  •  994
    Human cognitive acts are directed towards objects extended in space of a wide range of different types. What follows is a new proposal for bringing order into this typological clutter. The theory of spatially extended objects should make room not only for the objects of physics but also for objects at higher levels, including the objects of geography and of related disciplines. It should leave room for different types of boundaries, including both the bona fide boundaries which we find in the ph…Read more
  •  369
    Building on the writings of Wittgenstein on rule-following and deviance, Kristóf Nyíri advanced a theory of creativity as consisting in a fusion of conflicting rules or disciplines. Only such fusion can produce something that is both intrinsically new and yet capable of being apprehended by and passed on to a wider community. Creativity, on this view, involves not the breaking of rules, or the deliberate cultivation of deviant social habits, but rather the acceptance of enriched systems of rules…Read more
  •  331
    The New European Philosophy
    In János Kristóf Nyíri & Barry Smith (eds.), Philosophy and Political Change in Eastern Europe, Hegeler Institute. pp. 165-170. 1993.
    The paper seeks to indicate ways in which the crude distinction between Anglo-Saxon and Continental philosophy may have to be amended in light of recent developments in Eastern Europe. As is well known, the philosophy of science is to no small part a product of the universities of the Habsburg Empire (in Vienna, Prague, Lemberg/Lwow, etc.). Logic, too, has played a more significant role in Eastern Europe (not least in Poland) than in the philosophical cultures of Germany or France. For these and…Read more
  •  303
    The piece of wax takes on the form of the seal; but this occurs in a way that is largely indifferent to the particular constitution of the seal. Similarly, Aristotle says, ‘the sense is affected by what is coloured or flavoured or sounding, but it is indifferent as to what in each case the substance is’. We show that Brentano takes this Aristotelian account of the relation between sense and its objects as the basis for his theory of mind in the Psychology from an Empirical Standpoint.
  •  567
    A Theory of Granular Partitions
    In Matt Duckham, Michael F. Goodchild & Michael Worboys (eds.), Foundations of Geographic Information Science, Taylor & Francis. pp. 117-151. 2003.
    We have a variety of different ways of dividing up, classifying, mapping, sorting and listing the objects in reality. The theory of granular partitions presented here seeks to provide a general and unified basis for understanding such phenomena in formal terms that is more realistic than existing alternatives. Our theory has two orthogonal parts: the first is a theory of classification; it provides an account of partitions as cells and subcells; the second is a theory of reference or intentional…Read more
  •  1314
    Framework for formal ontology
    Topoi 2 (1): 73-85. 1983.
    The discussions which follow rest on a distinction, first expounded by Husserl, between formal logic and formal ontology. The former concerns itself with (formal) meaning-structures; the latter with formal structures amongst objects and their parts. The paper attempts to show how, when formal ontological considerations are brought into play, contemporary extensionalist theories of part and whole, and above all the mereology of Leniewski, can be generalised to embrace not only relations between c…Read more
  •  604
    CARO: The Common Anatomy Reference Ontology
    with Melissa Haendel, Fabian Neuhaus, David Osumi-Sutherland, Paula M. Mabee, José L. V. Mejino Jr, and Chris J. Mungall
    The Common Anatomy Reference Ontology (CARO) is being developed to facilitate interoperability between existing anatomy ontologies for different species, and will provide a template for building new anatomy ontologies. CARO has a structural axis of classification based on the top-level nodes of the Foundational Model of Anatomy. CARO will complement the developmental process sub-ontology of the GO Biological Process ontology, using it to ensure the coherent treatment of developmental stages, and…Read more
  •  679
    Biometaphysics
    In Robin Le Poidevin, Simons Peter, McGonigal Andrew & Ross P. Cameron (eds.), The Routledge Companion to Metaphysics, Routledge. pp. 537-544. 2009.
    While Darwin is commonly supposed to have demonstrated the inapplicability of the Aristotelian ontology of species to biological science, recent developments, especially in the wake of the Human Genome Project, have given rise to a new golden age of classification in which ontological ideas -- as for example in the Gene Ontology, the Cell Ontology, the Protein Ontology, and so forth -- are once again playing an important role. In regard to species, on the other hand, matters are more complex. We…Read more