Miguel García

Grounded theory, a research method born out of the social sciences field, offers a flexible technique that allows simultaneous data collection and processing. Researchers using this method immerse themselves in an area of study, focusing their observations on the data and taking into consideration not only their own interpretations, but also those of the other subjects involved, in order to strengthen their understanding of the social phenomena under examination. This text briefly describes the concept of grounded theory and uses concrete examples to illustrate how data are analysed from the standpoint of the stereotype as an object of study. La teoría fundamentada, nacida al interior de las ciencias sociales, es un método de investigación que posee una técnica flexible y que realiza simultáneamente la recolección y el procesamiento de los datos. En este método, el investigador se encuentra inmerso en el campo de estudio y sus observaciones se abocan al dato, considerando tanto su interpretación como la de los otros sujetos implicados, con la finalidad de fortalecer la comprensión del fenómeno social investigado. En este texto se describe brevemente la teoría fundamentada y cómo se analizan los datos mediante ejemplos concretos, que se presentan a partir del estereotipo como objeto de estudio.

The essential role of creativity has been highlighted in several human knowledge areas. Regarding the neural underpinnings of creativity, there is evidence about the role of left dorsolateral prefrontal cortex (DLPFC) and left inferior frontal gyrus (IFG) on divergent thinking (DT) and convergent thinking (CT). Transcranial stimulation studies suggest that the left DLPFC is associated with both DT and CT, whereas left IFG is more related to DT. However, none of the previous studies have targeted both hubs simultaneously and compared transcranial direct current stimulation (tDCS) and random noise stimulation (tRNS). Additionally, given the relationship between cognitive flexibility and creativity, we included it in order to check if the improvement in creativity may be mediated by cognitive flexibility. In this double-blind, between-subjects study, 66 healthy participants were randomly assigned to one of three groups (N = 22) that received a transcranial direct current stimulation (tDCS), transcranial random noise stimulation (tRNS), or sham for 20 min. The tDCS group received 1.5 mA with the anode over the left DLPFC and cathode over the left IFG. Locations in tRNS group were the same and they received 1.5 mA of high frequency tRNS (100–500 Hz). Divergent thinking was assessed before (baseline) and during stimulation with unusual uses (UU) and picture completion (PC) subtests from Torrance Creative thinking Test, whereas convergent thinking was evaluated with the remote association test (RAT). Stroop test was included to assess cognitive flexibility. ANCOVA results of performance under stimulation (controlling for baseline performance) showed that there were significant differences in PC (F = 3.35, p = 0.042, np2 = 0.10) but not in UU (F = 0.61, p = 0.546) and RAT (F = 2.65, p = 0.079) scores. Post-hoc analyses showed that tRNS group had significantly higher scores compared to sham (p = 0.004) in PC. More specifically, tRNS showed higher performance in fluency (p = 0.012) and originality (p = 0.021) dimensions of PC compared to sham. Regarding cognitive flexibility, we did not find any significant effect of any of the stimulation groups (F = 0.34, p = 0.711). Therefore, no further mediation analyses were performed. Finally, the group that received tDCS reported more adverse effects than sham group (F = 3.46, p = 0.035). Altogether, these results suggest that tRNS may have some advantages over tDCS in DT.

Some philosophers have argued that Wittgenstein’s hinges, the centrepiece of his book On Certainty, are the “ungrounded ground” on which knowledge rests. It is usually understood by this that hinges provide a foundation for knowledge without being themselves epistemically warranted. In fact, Wittgenstein articulates that hinges lack any truth-value and are neither justified nor unjustified. This inevitably places them wholly outside the categorial framework of JTB epistemology. What I call the “groundlessness interpretation”, inspired by OC 166, understands the fundamental pieces of our cognitive scaffolding this way. The view has been largely successful. I argue that this interpretation is incomplete for two basic reasons: first, it is not based on undisputed evidence; second, by assuming that hinges are committed to reality by epistemic fiat, it looks as if Wittgenstein is asking us to blindly trust them regardless of their actual content. Contrary to this, I argue that Wittgenstein describes hinges as illuminating world-pictures that reflect reality and are answerable to facts in a derivate way. As the book shows, hinges originate in our engagement with reality and, while considered unquestionable, could be challenged, reassessed, and replaced by new ones. This indicates that hinges are both the result of knowledge-acquisition and somewhat continuous with one’s set of beliefs. It follows that hinges are ultimately rational, and so, apt instruments to confront scepticism.

Some philosophers have argued that Wittgenstein’s hinges, the centrepiece of his book On Certainty, are the “ungrounded ground” on which knowledge rests. It is usually understood by this that hinges provide a foundation for knowledge without being themselves epistemically warranted. In fact, Wittgenstein articulates that hinges lack any truth-value and are neither justified nor unjustified. This inevitably places them wholly outside the categorial framework of JTB epistemology. What I call the “groundlessness interpretation”, inspired by OC 166, understands the fundamental pieces of our cognitive scaffolding this way. The view has been largely successful. I argue that this interpretation is incomplete for two basic reasons: first, it is not based on undisputed evidence; second, by assuming that hinges are committed to reality by epistemic fiat, it looks as if Wittgenstein is asking us to blindly trust them regardless of their actual content. Contrary to this, I argue that Wittgenstein describes hinges as illuminating world-pictures that reflect reality and are answerable to facts in a derivate way. As the book shows, hinges originate in our engagement with reality and, while considered unquestionable, could be challenged, reassessed, and replaced by new ones. This indicates that hinges are both the result of knowledge-acquisition and somewhat continuous with one’s set of beliefs. It follows that hinges are ultimately rational, and so, apt instruments to confront scepticism.

This paper addresses the 1996 cloning of Dolly the sheep, locating it within a long-standing tradition of animal breeding research in Edinburgh. Far from being an end in itself, the cell-nuclear transfer experiment from which Dolly was born should be seen as a step in an investigative pathway that sought the production of medically relevant transgenic animals. By historicising Dolly, I illustrate how the birth of this sheep captures a dramatic redefinition of the life sciences, when in the 1970s and 1980s the rise of neo-liberal governments and the emergence of the biotechnology market pushed research institutions to show tangible applications of their work. Through this broader interpretative framework, the Dolly story emerges as a case study of the deep transformations of agricultural experimentation during the last third of the twentieth century. The reorganisation of laboratory practice, human resources and institutional settings required by the production of transgenic animals had unanticipated consequences. One of these unanticipated effects was that the boundaries between animal and human health became blurred. As a result of this, new professional spaces emerged and the identity of Dolly the sheep was reconfigured, from an instrument for livestock improvement in the farm to a more universal symbol of the new cloning age.

Resumen. El siguiente artículo muestra el estado actual de la Responsabilidad Empresarial enMéxico y su efecto en el Riesgo medido a través del Costo de Capital. Para ello, revisamos lasprincipales teorías que muestran que el uso de prácticas sociales en Estados Unidos provocandisminución del riesgo y por ende del Costo de Capital, Aras y Crowther, Richardson yWelker y Diamond y Verrechia. Con el fin de contrastar que las empresas SocialmenteResponsables tienen costos de capital menores consideramos como variable de desempeño social eldistintivo que otorga el Centro Mexicano de Filantropía y por otra parte para calcular elriesgo consideramos el costo de capital a través de la metodología del Capital Asset Price Modelo. Encontramos que las empresas que son socialmente responsables tienen costos de capitalsuperiores que las que no son responsables y que el rendimiento de acciones es superior en lasempresas no responsables, por lo que el diferencial de riesgo vs rendimiento es superior en lasempresas no socialmente responsables. Lo anterior rechaza la hipótesis y contrasta con la realidadempírica de otros estudios.Palabras claves. Distintivo de ESR, CEMEFI, costo de capital, riesgo, rentabilidad de acciones,Bolsa de Valores. The following article shows the current status of the corporate responsibility inMexico and their effect on risk measured by the cost of capital. To do this, we review the maintheories that show that social practices in the United States leads to decrease risk and hence the costof Capital Aras and Crowther, Richardson and Welker and Diamond y Verrechia. In order to contrast that socially responsible companies have lower capital costs we considersocial performance variable the distinction conferred by the Mexican Center for Philanthropy and the cost of capital it estimate on the methodology of the Capital Asset Price model. We find that companies that are socially responsible have capital costs higher than thosethat are not responsible. It rejects the hypothesis and contrasts with the empirical reality of otherstudies.Keywords. CSR distintive, CEMEFI, cost of capital, risk, return in shares, Capital Market Securities.

En este texto se plantea el comienzo de un tratado de filosofía primera que divide los problemas de ésta en asuntos de ontología, agatología y lógica. Se presentan luego las bases de la lógica como teoría del conocimiento y las bases de la ontología como teoría de las pluralidades. Se critican las posiciones aparentemente más plausibles, en dirección a mostrar cómo el peculiar fenomenismo defendido por Husserl en su madurez filosófica es la mejor de las soluciones globales para la problemática lógica.The text puts forward how to begin an exposition of prima philosophia dividing its problems in ontological, agathological and logical ones. The foundations of logics as the theory of knowledge and the foundations of ontology as the theory of pluralities are explored by the way of critizing apparently plausible solutions. The aim is to guess why the peculiar phenomenalism sustained by Husserl in his mature philosophy is the best approach to logical nuclear problems.

En este trabajo se propone una revisión de la fenomenología de la vida de Michel Henry y su relación con la intencionalidad, tal como esta es pensada en y por Husserl. Se pasa revista al modo en el que el fundador del método fenomenológico se ocupa de cuestiones centrales de la fenomenología de la vida, así como de la forma en la que Henry habla de la vida, la autodonación, la autorevelación, la verdad, el cuerpo originario o absoluto, etc. La tesis es que en el fenomenólogo francés no se trata, en sentido propio, de una inversión de la intencionalidad, sino de una “absorción en sí misma”.

This article proposes a new bi-directional way of understanding the convergence of biology and computing. It argues for a reciprocal interaction in which biology and computing have shaped and are currently reshaping each other. In so doing, we qualify both the view of a natural marriage and of a digital shaping of biology, which are common in the literature written by scientists, STS, and communication scholars. The DNA database is at the center of this interaction. We argue that DNA databases are spaces of convergence for computing and biology that change in form, meaning, and function from the 1960s to the 2000s. The first part of the article shows how, in the 1980s, DNA sequencing shifted from passively incorporating computers to be increasingly modeled in digital coding and decoding. Information retrieval algorithms, reciprocally, were altered according to the peculiarities of DNA in the first sequence-storage databases. The second part of the article investigates the impact of these reciprocal interactions and globalization on the organization of research centers, ways of conducting big science, and scientific values. Through convergence and new technologies such as data mining, biology and computing were transformed technologically, institutionally, and culturally into a new bio-data enterprise called genomics.

This article argues for two related theses. First, it defends a general thesis: any kind of necessity, including metaphysical necessity, can only be known a priori. Second, however, it also argues that the sort of a priori involved in modal metaphysical knowledge is not related to imagination or any sort of so-called epistemic possibility. Imagination is neither a proof of possibility nor a limit to necessity. Rather, modal metaphysical knowledge is built on intuition of philosophical categories and the structures they form

On 26 June 2000, during the presentation of the Human Genome Project's first draft, Bill Clinton, then President of the United States, claimed that "today we are learning the language in which God created life".1 Behind his remarks lay a story of more than half a century involving the understanding of DNA as information. This paper analyses that story, discussing the origins of the informational view of our genes during the early 1950s, how such a view affected the research on the genetic code (1950s and '60s) and the transformation of the information idea in the context of DNA sequencing and bioinformatics ('80s and '90s). I suggest that the concept of DNA as information reached a climax with the proposal of the Human Genome Project (HGP), but is currently facing a crisis coinciding with the questioning of the information society. Finally, I discuss the emergence of systems biology as an alternative paradigm.

The object of this paper is to offer a conception of singular causality that lies between two main views in the literature, which I take to be paradigmatically represented by David Armstrong (1997) and by Michael Tooley (1987, 1990) respectively. Armstrong maintains that there is singular causation wherever there are singular facts that instantiate causal laws; these facts are otherwise independent regularities. Tooley maintains that singular causation is independent of causal laws together with any other non-causal fact. My own view is that Armstrong’s account is too weak to conform a singularist position, as in his view singular causal relations are finally dependent on universal causation. On the other hand, Tooley’s account is too strong to be causal, as causation dissolves into a purely external and mysterious connection that is not even Humean -not even regularities play a role in its establishment. I want to maintain that there exists a middle way that correctly characterizes the spirit of singular causation, and that can be stated by (CS): (CS) Singular causality is metaphysically independent of universal causality. Neither Tooley nor Armstrong would admit (CS) as an appropriate defining thesis for causal singularism. In what follows, I consider different causal situations existing in the literature, with the purpose of analysing singular causation, arguing against Tooley and Armstrong's views, and defending (CS) instead. If my reasons are accepted, Armstrong’s position, rather than being singular in spirit, results into a form of causal universalism. I will also reject Tooley’s singularism as an extreme counterintuitive form of hyperrealism. Some consequences for causation are immediate. In particular, that singular causal relations are tropes, i.e., individual relations.

Practice theory has lately taken a turn towards modelling the evolution of practices, which appear situated at the centre of the study of social action. I argue in this paper, following previous criticisms, that such centrality can be revised in order to better incorporate elements of agency and normativity, which are much determinant of the emergence and development of practices. The aim of this paper is to propose an alternative heuristic which advances on lefebvrean trialectics, in order to better account for process in the study of practices. For this I rely on previous concepts from anthropology and sociology, such as fetishisation, ritualisation and bricolage. A relevant case study is merely outlined in order to illustrate how such a conceptual framework can identify agencies and situate practices in relation to power structures and performance at an early stage within the research process.

The effect of ASDEX Upgrade edge localized mode -mitigation coils on fast ion wall loads was studied with the fast particle following Monte Carlo code ASCOT. Neutral beam injected particles were simulated in two AUG discharges both in the presence and in the absence of the magnetic field perturbation induced by the eight newly installed in-vessel coils. In one of the discharges beams were applied individually, making it a useful basis for investigating the effect of the coils on different beams. However, no ELM mitigation was observed in #26476, probably due to the low plasma density. Therefore, another discharge demonstrating clear ELM mitigation was also studied. The magnetic perturbation due to the in-vessel coils has a significant effect on the fast particle confinement, but only when total magnetic field, B tot, is low. When B tot was high, the perturbation did not increase the losses, but merely resulted in redistribution of the wall power loads. Hence, it seems to be possible to achieve ELM mitigation using in-vessel coils, while still avoiding increased fast ion losses, by simply using a strong B tot. Preliminary comparisons between simulated and experimental fast ion lost detector signals show a reasonable correspondence. © 2012 IAEA, Vienna.