Chuang Liu

This paper examines the justifications for using infinite systems to ‘recover’ thermodynamic properties, such as phase transitions, critical phenomena, and irreversibility, from the micro-structure of matter in bulk. Section 2 is a summary of such rigorous methods as in taking the thermodynamic limit to recover PT and in using renormalization group approach to explain the universality of critical exponents. Section 3 examines various possible justifications for taking TL on physically finite systems. Section 4 discusses the legitimacy of applying TL to the problem of irreversibility and assesses the repercussions for its legitimacy on its home turf.

Kripke has taken the Gödel case as a counterexample for reference descriptivism. Machery et al. question the validity of Kripke’s case and had conducted empirical studies to show its inadequacy. Experimental data suggest intuitions on this matter vary both across and within cultures. However, there is a descriptive ambiguity, we argue, in Kripke’s Gödel case, for people associate different types of descriptions with proper names, such as the description of brute facts and the description of social facts. We argue in this paper with experimental data that the descriptive ambiguity exists and affects the actual ratio of Kripkeans in reference. This result flaws Machery et al.’s interpretation on empirical research, but does not challenge their claim on cross-cultural divergence. In fact, there are more East Asian descriptivists than Machery et al. expected.

The use of models to scientifically represent and study reality is widely recognized with good reasons as indispensable for the practice of science. Because models, unlikely pure verbal representation, are justifiably regarded as vehicles of representation that are not truth-apt, philosophical questions are natural raised concerning the nature of such vehicles and how they represent. A sizeable literature generated in recent years explores the possibility that ''scientific models are works of fiction''. Idealization and other similar strategies are often taken to be the means by which models are made. Arguing against this last claim, the thesis of this article is that most models in science are not fictional. The author argues against the idea that idealization is the means by which models of typically unobservable systems or mechanisms are made.

This paper contains four variations on Duhem's theme about the contrast between the abstract French mind and the concrete British mind. The first variation brings out the real contrast between two types of methods and their results: the A method or models and the C method or models. The second variation gives a critical discussion of the Callender-Cohen deflationary contruel of scientific representation. The third variation discusses Russell's structuralism in connection to the theme. And the fourth variation critically discusses the relationship between models and fiction in connection to the distinction between the A-models and the C-models. A coda maps out without sufficiently detailed arguments the author's view on the nature of the C-models and why they, and only they, can be viewed as fully fictional.

Fictional models in science -- The hypothetical versus the fictional -- What is wrong with the new fictionalism of scientific models? -- Re-inflating the conception of scientific representation -- Idealization, confirmation, and scientific realism -- Laws and models in a theory of idealization -- Approximation and its measures -- Approximation, idealization, and the laws of nature -- Coordination of space and unity of science -- Gauge gravity and the unification of natural forces -- Models and theories II: issues and applications -- Models and theories I: the semantic view revisited -- Explaining quantum spontaneous symmetry breaking -- Review: symmetries in physics: philosophical reflections -- Classical spontaneous symmetry breaking -- Spontaneous symmetry breaking and chance in a classical world -- Approximations, idealizations, and models in statistical mechanics -- Infinite systems in SM explanations: thermodynamic limit, renormalization (semi-) groups, and irreversibility -- Explaining the emergence of cooperative phenomena -- A possible unified understanding of probabilistic objects -- Particularism and holism revisited -- Potential, propensity and categorical realism -- The Aharonov-Bohm effect and the reality of wave packets -- Realism and spacetime: of arguments against metaphysical realism and manifold realism -- Gauge invariance, Cauchy problem, indeterminism, and symmetry breaking -- Is there a relativistic thermodynamics? a case study of the meaning of special relativity.

This volume contains the contributed papers of invitees to SEMS 2012 who have also given talks at the conference. The invitees are experts in philosophy of science and technology from Asia (besides China), Australia, Europe, Latin America, North America, as well as from within China. The papers in this volume represent the latest work of each researcher in his or her expertise; and as a result, they give a good representation of the cutting-edge researches in diverse areas in different parts of the world.

Purpose To investigate the reliability and accuracy of two pseudo-continuous arterial spin labeling sequences, using two-dimensional gradient-echo echo planar imaging and 3D gradient and spin echo as the readout, respectively. Materials and Methods Each sequence was performed twice 4 weeks apart on six normal control subjects, six elderly subjects with mild cognitive impairment, and one participant with Alzheimer's disease. Eight of these subjects also underwent H 215O positron emission tomography scans on the same day or proximal to their second MRI scan. The longitudinal repeatability of EPI and GRASE pCASL were evaluated with the intraclass correlation coefficient and within-subject coefficient of variation. Results The ICCs of global perfusion measurements were 0.697 and 0.413 for GRASE and EPI based pCASL respectively. GRASE pCASL also demonstrated a higher longitudinal repeatability for regional perfusion measurements across 24 regions-of-interests compared with EPI pCASL. When compared with PET, EPI pCASL showed a higher degree of spatial correlation with PET than GRASE pCASL, although the difference was not statistically significant. Conclusion The 3D GRASE pCASL offers better repeatability than 2D EPI pCASL, thereby may provide a reliable imaging marker for the evaluation of disease progression and treatment effects in MCI and early AD subjects. © 2013 Wiley Periodicals, Inc.

Posttranslational modification of proteins and peptides is important for diverse biological processes in plants and animals. The paucity of heterologous expression systems for PTMs and the technical challenges associated with chemical synthesis of these modified proteins has limited detailed molecular characterization and therapeutic applications. Here we describe an optimized system for expression of tyrosine-sulfated proteins in Escherichia coli and its application in a bio-based crop protection strategy in rice.

Relativistic Thermodynamics of equilibrium processes has remained a strange chapter in the history of modern physics. It was established by Planck in 1908 as a simple application of Einstein's special theory of relativity. Einstein himself made substantial contributions and its final product remained officially unchallenged until 1965. In 1952, however, at the end of his career, Einstein challenged the theory in his correspondence with von Laue. Many of his unpublished suggestions anticipated the major works in the debate of the 1960s. The debate on the theory of RTD started in 1965 and lasted over a decade. In the end, no satisfactory solution was found even though every possible alternative seemed to have been entertained. Most participants contended that the choice among the alternatives was a matter of convention, depending on how one defines the basic quantities in RTD. ;This dissertation provides a critical study of the history of RTD and a philosophical investigation of its foundations. The first half is a critical study of the origin and the early development of RTD; which culminated in a detailed and, to my best knowledge, the first thorough discussion of the Einstein-von Laue correspondence. In the second half, after the complexity of the problem is described in chapter 5, a solution is found for the whole controversy based on Anderson's sharp insights on the different meanings of the relativity principles. Unless one can prove that pure thermodynamic quantities are geometrical objects, there is no need to look for the Lorentz-Transformations for those quantities; but they do not qualify as geometrical objects for they can only be defined in the rest frame of a system. ;This study also shows how profound the relativity principles are, how difficult it is to grasp their real meaning, and how physicists were led astray by paying too much attention to the formalism of a theory but too little to the soundness of the basic assumptions from which the theory derived