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69Long-lasting coma.Functional Neurology 29 (3): 201-205. 2014.In this report, we describe the case of a patient who has remained in a comatose state for more than one year after a traumatic and hypoxic brain injury. This state, which we refer to as long-lasting coma (LLC), may be a disorder of consciousness with significantly different features from those of conventional coma, the vegetative state, or brain death. On the basis of clinical, neurophysiological and neuroimaging data, we hypothesize that a multilevel involvement of the ascending reticular acti…Read more
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62Information Flow in the Brain: Ordered Sequences of Metastable StatesInformation 8 (1): 22. 2017.In this brief overview paper, we analyse information flow in the brain. Although Shannon’s information concept, in its pure algebraic form, has made a number of valuable contributions to neuroscience, information dynamics within the brain is not fully captured by its classical description. These additional dynamics consist of self-organisation, interplay of stability/instability, timing of sequential processing, coordination of multiple sequential streams, circular causality between bottom-up an…Read more
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59Topodynamics of metastable brainsPhysics of Life Reviews 21 1-20. 2017.The brain displays both the anatomical features of a vast amount of interconnected topological mappings as well as the functional features of a nonlinear, metastable system at the edge of chaos, equipped with a phase space where mental random walks tend towards lower energetic basins. Nevertheless, with the exception of some advanced neuro-anatomic descriptions and present-day connectomic research, very few studies have been addressing the topological path of a brain embedded or embodied in its …Read more
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58Brain Projective Reality: Novel Clothes for the EmperorPhysics of Life Reviews 21 46-55. 2017.First of all, we would like to gratefully thank all commentators for the attention and effort they have put into reading and responding to our review paper [this issue] and for useful observations that suggest novel applications for our framework. We understand and accept that some of our claims might appear controversial and raise skepticism, because the overall neural framework we have proposed is difficult to frame in established categories, given its strong multidisciplinary character. To ma…Read more
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58Based on previous studies implicating increased functional connectivity within the self-referential brain network in major depressive disorder (MDD), and considering the functional roles of three distinct modules of such brain net (responsible for three-dimensional components of Selfhood) together with the documented abnormalities of self-related processing in MDD, we tested the hypothesis that patients with depression would exhibit increased connectivity within each module of the self-referenti…Read more
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57EEG-Guided Meditation: A Personalized Approach.Journal of Physiology-Paris 109 (4-6): 180-190. 2015.The therapeutic potential of meditation for physical and mental well-being is well documented, however the possibility of adverse effects warrants further discussion of the suitability of any particular meditation practice for every given participant. This concern highlights the need for a personalized approach in the meditation practice adjusted for a concrete individual. This can be done by using an objective screening procedure that detects the weak and strong cognitive skills in brain functi…Read more
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54Alterations in the three components of selfhood in persons with post-traumatic stress disorder symptoms: A pilot qEEG neuroimaging studyOpen Neuroimaging Journal 12 42-54. 2018.Background and Objective: Understanding how trauma impacts the self-structure of individuals suffering from the Post-Traumatic Stress Disorder (PTSD) symptoms is a complex matter and despite several attempts to explain the relationship between trauma and the “Self”, this issue still lacks clarity. Therefore, adopting a new theoretical perspective may help understand PTSD deeper and to shed light on the underlying psychophysiological mechanisms. Methods: In this study, we employed the “thre…Read more
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54Actual physical potentiality for consciousnessAmerican Journal of Bioethics Neuroscience 9 (1): 24-25. 2018.Dr. Vukov analyzing patients with disorders of consciousness, proposed that medical well-regarded policy recommendations cannot be justified by looking solely to patients’ actual levels of consciousness (minimally conscious state – MCS versus vegetative state – VS), but that they can be justified by looking to patients’ potential for consciousness. One objective way to estimate this potential (actual physical possibility) is to consider a neurophysiologically informed strategy. Ideally such stra…Read more
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54Do we need a theory-based assessment of consciousness in the field of disorders of consciousness?Frontiers in Human Neuroscience 8 402. 2014.Adequate assessment of (un)consciousness is not only of theoretical interest but also has a practical and ethical importance, especially when it comes to disorders of consciousness (DOC). Accurately determining the presence or absence of consciousness in patients with DOC allows informed decisions to be made about long-term care support, referral for rehabilitation, pain management and withdrawal of life support. We believe that a theoretical account of what conscious experience is and how it em…Read more
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53Mind the physics: Physics of mindPhysics of Life Reviews 25 75-77. 2018.The target paper of Schoeller, Perlovsky, and Arseniev is an essential and timely contribution to a current shift of focus in neuroscience aiming to merge neurophysiological, psychological and physical principles in order to build the foundation for the physics of mind. Extending on previous work of Perlovsky et al. and Badre, the authors of the target paper present interesting mathematical models of several basic principles of the physics of mind, such as perception and cognition, concepts and …Read more
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52Electroencephalogram (EEG) recordings are increasingly used to evaluate patients with disorders of consciousness (DOC) or assess their prognosis outcome in the short-term perspective. However, there is a lack of information concerning the effectiveness of EEG in classifying long-term (many years) outcome in chronic DOC patients. Here we tested whether EEG operational architectonics parameters (geared towards consciousness phenomenon detection rather than neurophysiological processes) could be us…Read more
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49Syntax meets semantics during brain logical computationsProgress in Biophysics and Molecular Biology 140 133-141. 2018.The discrepancy between syntax and semantics is a painstaking issue that hinders a better comprehension of the underlying neuronal processes in the human brain. In order to tackle the issue, we at first describe a striking correlation between Wittgenstein's Tractatus, that assesses the syntactic relationships between language and world, and Perlovsky's joint language-cognitive computational model, that assesses the semantic relationships between emotions and “knowledge instinct”. Once establishe…Read more
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48Trait lasting alteration of the brain default mode network in experienced meditators and the experiential selfhoodSelf and Identity 15 (4): 381-393. 2016.Based on the finding in novices that four months of meditation training significantly increases frontal default mode network (DMN) module/subnet synchrony while decreasing left and right posterior DMN modules synchrony, the current study tested the prediction whether experienced meditators (those who are practising meditation intensively for several years) had a change in the DMN “trinity” of modules as a baseline trait characteristic and whether this change is in a similar direction as in the n…Read more
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47Placing Pure Experience of Eastern Tradition into the Neurophysiology of Western TraditionCognitive Neurodynamics 13 (1): 121-123. 2019.While the presence or absence of consciousness plays the central role in the moral/ethical decisions when dealing with patients with disorders of consciousness (DOC), recently it is criticized as not adequate due to number of reasons, among which are the lack of the uniform definition of consciousness and consequently uncertainty of diagnostic criteria for it, as well as irrelevance of some forms of consciousness for determining a patient’s interests and wishes. In her article, Dr. Specker Sulli…Read more
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42Depersonalization Puzzle: A New View from the Neurophenomenological Selfhood PerspectiveJournal of Neurophilosophy 1 (2): 181-202. 2022.While there is still a limited understanding of the Selfhood phenomenon, an emerging consensus is that the experiential Selfhood refers to a sense of the undergoing experience in its implicit first-person mode of givenness that is immediately and tacitly given as “mine”. It is also evident that there are phenomenological disruptions within self-consciousness ranging from normal everyday short-lived dissociative episodes to pathological, intense and prolonged forms of dissociative experience clas…Read more
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41Brain space and time in mental disorders: Paradigm shift in biological psychiatryInternational Journal of Psychiatry in Medicine 54 (1): 53-63. 2019.Contemporary psychiatry faces serious challenges because it has failed to incorporate accumulated knowledge from basic neuroscience, neurophilosophy, and brain–mind relation studies. As a consequence, it has limited explanatory power, and effective treatment options are hard to come by. A new conceptual framework for understanding mental health based on underlying neurobiological spatial-temporal mechanisms of mental disorders (already gained by the experimental studies) is beginning to emerge.
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40Brain-mind operational architectonics: At the boundary between quantum physics and Eastern metaphysicsPhysics of Life Reviews 31 122-133. 2019.The Operational Architectonics (OA) of brain-mind functioning is a theory that unifies brain and mind through nested and dynamic hierarchy of electromagnetic brain fields. Recently, it has been enriched by concepts from physics like time, space, entropy, and self-organized criticality. This review paper advances OA theory further by delving into the foundations of quantum physics and Eastern metaphysics in relation to mind function. We aim to show that the brain-mind OA is the boundary between a…Read more
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37After HumanFutura 4 60-74. 2018.Human beings are in the midst of very powerful shifts in our understanding of what it means to be a human. There is a non-trivial chance that sometime in the future humanity will transform itself, leading to an emergence of posthumans with God-like qualities – Homo Deificatio. Such a transformation has great potential for both good and bad. Posthumanism seeks to improve human nature, increase the human life- and health-span, extend its cognitive and physical capacities, and broaden its mastery o…Read more
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29Altered Structure of Dynamic Electroencephalogram Oscillatory Pattern in Major Depression.Biological Psychiatry 77 (12): 1050-1060. 2015.Research on electroencephalogram (EEG) characteristics associated with major depressive disorder (MDD) has accumulated diverse neurophysiologic findings related to the content, topography, neurochemistry, and functions of EEG oscillations. Significant progress has been made since the first landmark EEG study on affective disorders by Davidson 35 years ago. A systematic account of these data is important and necessary for building a consistent neuropsychophysiologic model of MDD and other affecti…Read more
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25The Selfhood-Components Dynamics in the Spectrum of Discrete Normotypical and Pathological Modes (2nd ed.)Journal of Neurophilosophy 2 (2): 402-431. 2023.In this first-of-its-kind neurophenomenological study we investigated the dynamic configuration and the levels of variability of the “Self”-, “Me”-, and “I”- components that comprise a complex experiential Selfhood across 16 distinct modes covering a range of healthy-normal, altered, and pathological brain states. The phenomenology was addressed by examining the mental structures of subjective self-experience, and for the neurophysiological counterpart, we used electroencephalogram analysis to g…Read more
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18Attentional State : From Automatic Detection to Willful Focused ConcentrationIn Giorgio Marchetti, Giulio Benedetti & Ahlam Alharbi (eds.), Attention and Meaning. The Attentional Basis of Meaning, Nova Science Publishers. pp. 133-150. 2015.Despite the fact that attention is a core property of all perceptual and cognitive operations, our understanding of its neurophysiological mechanisms is far from complete. There are many theoretical models that try to fill this gap in knowledge, though practically all of them concentrate only on either involuntary (bottom-up) or voluntarily (top-down) aspect of attention. At the same time, both aspects of attention are rather integrated in the living brain. In this chapter we attempt to conceptu…Read more
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Contemplating on the Nature of Selfhood in DoC Patients: Neurophenomenological PerspectiveJournal of Integrative Neuroscience 22 (1): 23. 2023.Medical well-regarded policy recommendations for patients with disorders of consciousness (DoC) are almost exclusively relied on behavioural examination and evaluation of higher-order cognition, and largely disregard the patients’ self. This is so because practically establishing the presence of self-awareness or Selfhood is even more challenging than evaluating the presence of consciousness. At the same time, establishing the potential (actual physical possibility) of Selfhood in DoC patients i…Read more
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Patients with Disorders of Consciousness: Are They Nonconscious, Unconscious, or Subconscious? Expanding the DiscussionBrain Sciences 13 (5): 814. 2023.Unprecedented advancements in the diagnosis and treatment of patients with disorders of consciousness (DoC) have given rise to ethical questions about how to recognize and respect autonomy and a sense of agency of the personhood when those capacities are themselves disordered, as they typically are in patients with DoC. At the intersection of these questions rests the distinction between consciousness and unconsciousness. Indeed, evaluations of consciousness levels and capacity for recovery have…Read more
Andrew And Alexander Fingelkurts
BM-Science - Brain and Mind Technologies Research Centre
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BM-Science - Brain and Mind Technologies Research CentreOther
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