Maria Lopez

The versatile clustered regularly interspaced short palindromic repeats (CRISPR)/Cas system has emerged as a promising technology for therapy and molecular diagnosis. It is especially suited for overcoming viral infections outbreaks, since their effective control relies on an efficient treatment, but also on a fast diagnosis to prevent disease dissemination. The CRISPR toolbox offers DNA‐ and RNA‐targeting nucleases that constitute dual weapons against viruses. They allow both the manipulation of viral and host genomes for therapeutic purposes and the detection of viral nucleic acids in “Point of Care” sensor devices. Here, we thoroughly review recent advances in the use of the CRISPR/Cas system for the treatment and diagnosis of viral deleterious infections such as HIV or SARS‐CoV‐2, examining their strengths and limitations. We describe the main points to consider when designing CRISPR antiviral strategies and the scientific efforts to develop more sensitive CRISPR‐based viral detectors. Finally, we discuss future prospects to improve both applications. Also see the video abstract here: https://www.youtube.com/watch?v=C0z1dLpJWl4.

There can be no doubt that discrimination based on sex, race, ethnicity, religion or beliefs should not be tolerated in academia. Surprisingly, however, in recent years, policies of Diversity, Inclusion and Equity (DIE), officially introduced to counteract discrimination, have increasingly led to quite the opposite result: the exclusion of individuals who do not share a radical 'woke' ideology on identity politics (feminism, other gender activisms, critical race theory, etc.), and to the suppression of the academic freedom to discuss such dogmas. This subversion of academia — disguised Trojan-horse style as universal human rights advocacy — is unacceptable because academia must be politically neutral and protect freedom of speech, a cornerstone of professional scholarly activity without which universities as we know them will slowly but surely suffocate. Our purpose here is to put together some particularly illustrative cases of such repression in a single book, testifying to a ubiquitous trend within western culture, irreducible to a few isolated complaints. The essays contained here illustrate the abuse of power, censorship and witch-hunts at many universities and research centres in the name of DIE. List of coauthors in alphabetical order: Dorian Abbot, Tomonori Agoh, Gerhard Amendt, Ivar Arpi, David Benatar, Peter Boghossian, Civitas Research Team, David Díaz Pardo de Vera, Pedro Domingos, Janice Fiamengo, Étienne Forest, Jorge Gibert Galassi, Norman Goldstuck, José L. González Quirós, Lawrence M. Krauss, Patrick LaBelle, Martín López Corredoira, Heather Mac Donald, Martin Malmgren, Jordan Peterson, Constantin Polychronakos, Erik. J. Olsson, Philip C. Salzman, Alessandro Strumia, Tom Todd, Andrei Yafaev.

ResumenLa autora introduce al lector en la sociofenomenología de la vida cotidiana de A. Schütz desde una lectura hermenéutica de “El Quijote”. Se detiene en el análisis schütziano de las estructuras de relevancias presentes en el universo quijotesco, ilustrando con citas de la obra de Cervantes y comentarios de las mismas las diversas construcciones sociales de los mundos de la vida habitados por los diferentes personajes, principalmente por Don Quijote y Sancho. Las articulaciones de estas realidades múltiples van aclarando el sentido del subuniverso quijotesco y el lugar del mismo en el seno del mundo de la vida compartido. Esas articulaciones se traducen en diferentes relaciones intersubjetivas que van reconfigurando el mundo social de don Quijote. A modo de conclusión, la autora reinterpreta la “locura” quijotesca de acuerdo con la estructura de relevancias.Palabras clavesociofenomenología, Schütz, mundo de la vida, D. QuijoteAutor initiates reader into A. Schütz´s Sociophenomenology of the daily life by means of the phenomenological hermeneutics of “The Quixot”. She focusses on the schützian analysis of the structures of relevances in the quixotic universe. The different social constructions of the lifeworlds are illustrated through Cervantes book´s quotations and comments, mainly by the D. Quixot and Sancho inhabited worlds. The articulations of these multiple realities go clarifying the sense of the quixotic subuniverse and its place in the common lifeworld´s bossom. Such articulations are translated into different intersubjetive relationships which reshape the Quixot´s social world. As a conclusion, author reinterpretes the quixotic “madness” in line with the structure of the relevances.KeywordsSociophenomenology, Schütz, Lifeworld, D. Quixot

The development of assistive robotics and anthropomorphic AI allows machines to increasingly enter into the daily lives of human beings and gradually become part of their lives. Robots have made a strong entry in the field of assistive behaviour. In this chapter, we will ask to what extent technology can satisfy people’s personal needs and desires as compared to human agents in the field of care. The industry of assistive technology burst out of the gate at the beginning of the century with very strong innovation and development and is currently attracting large sources of public and private investment and public attention. We believe that a better-defined and more fundamental philosophical-ethical analysis of the values at stake in care robots is needed. To this end, we will focus on the current status of care robots (types of care robots, their functioning and their design) and we will provide a philosophical-ethical analysis that offers a solid framework for the debate surrounding the potential risks and benefits of implementing assistive robots in people’s daily lives.