Andrea Lavazza

We start by introducing the idea of echo chambers. Echo chambers are social and epistemic structures in which opinions, leanings, or beliefs about certain topics are amplified and reinforced due to repeated interactions within a closed system; that is, within a system that has a rather homogeneous sample of sources or people, which all share the same attitudes towards the topics in question. Echo chambers are a particularly dangerous phenomena because they prevent the critical assessment of sources and contents, thus leading the people living within them to deliberately ignore or exclude opposing views. In the second part of this paper, we argue that the reason for the appearance of echo chambers lies in the adoption of what we call ‘epistemic vices’. We examine which vices might be responsible for their emergence, and in doing so, we focus on a specific one; ‘epistemic violence’. In assessing and evaluating the role of this epistemic vice, we note that it can be triggered by epistemic contexts characterized by high stakes that may turn ordinary intellectual virtues (such as skepticism) into vices (such as denialism). In the third part of this contribution, we suggest a way to deal with echo chambers. The solution focuses on advocating a responsibilist pedagogy of virtues and vices that -we claim- might be capable of preventing their emergence.

While research to improve memory or counter decay caused by neurodegenerative diseases has a fairly long history, scientific attempts to erase memories are very recent. The use of non-invasive brain stimulation for memory modulation represents a new and promising application for the treatment of certain disorders [such as Post-Traumatic Stress Disorder ]. However, numerous ethical issues are related to memory intervention. In particular, the possibility of using forms of non-invasive brain stimulation requires to distinguish treatment interventions from the enhancement of the healthy. Furthermore, a range of important societal and legal concerns arise when manipulating memories. In this short contribution, we address some of the most significant ethical, social, and legal implications surrounding the application of memory-modulation techniques and offer a series of reflections and considerations, which we hope can be of use to guide -and perhaps regulate- their potential, future implementation in society.

BackgroundThe Covid-19 pandemic caused situations where, in some hospitals, there were more patients in need of urgent treatment in intensive care units (ICU) than were available. In particular, there were not sufficient ventilators or critical care resources for all patients in danger of dying from respiratory failure or other organ failures.DiscussionAs the “first come, first served” criterion was not considered adequate, more nuanced and fairer clinical criteria were proposed to assess whom to treat first. One type of patients that has not been considered in the literature so far is that of “important patients”, individuals that many people might consider worthy of priority treatment for the contribution they made or might make to society as a whole.SummaryIn this article, we discuss the moral insights behind the possible treatment of “important patients” and suggest a supererogatory solution of voluntary renunciation/withdrawal. Details of the proposal are explained, and potential objections are addressed.

Background The 2020-2021 coronavirus (Covid-19) pandemic is just the latest epidemic event that requires us to rethink and change our understanding of health. Health should no longer be conceived only in relation to human beings, but in unitary terms, as a dimension that connects humans, animals, plants, and the environment (holistic view, One Health). In general, alterations occurring in this articulated chain of life trigger a domino effect. Methodology In this paper, we review the One Health paradigm in the light of the Covid-19 pandemic and distinguish two approaches within it that might be dubbed the Prudent one and the Radical one. Each approach is structured in three levels – epistemological, medical, and ethical. Results In this way, we show how we humans can better address the pandemic today and how, in the future, we can treat the whole living system better, by renouncing our anthropocentric perspective on health. Conclusion We hold that the Prudent approach can be very helpful, and we discuss the medical and ethical issues related to it. We also consider the Radical view and the epistemological turn it requires compared to the Prudent one.

We begin by introducing our readers to the Extended Mind Thesis and briefly discuss a series of arguments in its favour. We continue by showing of such a theory can be resisted and go on to demonstrate that a more conservative account of cognition can be developed. We acknowledge a stalemate between these two different accounts of cognition and notice a couple of issues that we argue have prevented further progress in the field. To overcome the stalemate, we propose to focus on the ethical implications of these theories. We link work conducted on the Extended Mind Thesis with contemporary transhumanist research and claim that extended may be ethically preferred over embedded because it is a more progressive and inclusive theory.

This critical essay evaluates the potential integration of distinct kinds of expertise in policymaking, especially during situations of critical emergencies, such as the COVID-19 pandemic. This article relies on two case studies: herd immunity and restricted access to ventilators for disabled people. These case studies are discussed as examples of experts’ recommendations that have not been widely accepted, though they were made within the boundaries of expert epistemic authority. While the fundamental contribution of biomedical experts in devising public health policies during the COVID-19 pandemic is fully recognized, this paper intends to discuss potential issues and limitations that may arise when adopting a strict expert-based approach. By drawing attention to the interests of minorities, the paper also claims a broader notion of “relevant expertise.” This critical essay thus calls for the necessity of wider inclusiveness and representativeness in the process underlying public health policymaking.

Riassunto : Per la teoria della documentalità gli oggetti sociali sono atti iscritti e per la teoria della mente estesa le menti si estendono a processi o dispositivi esterni al corpo. Pur per motivi diversi, le due teorie convergono nel ridurre le differenze fra menti e documenti, e hanno a loro supporto la dimensione semiotica di menti e documenti; eppure, in una certa lettura, tali teorie risultano implausibili se si considera che le proprietà delle cose che chiamiamo “menti” non sono identiche alle proprietà delle cose che chiamiamo “documenti”. Ciò chiama in causa una implicita tesi comune alle due teorie, quella di un esternismo forte che può essere messo in discussione in favore di un esternismo moderato o interazionista. Parole chiave : Diritto; Documentalità; Esternismo; Oggetti sociali; Ontologia sociale; Mente estesa; Maurizio Ferraris Minds are not documents: In the theory of documentality, social objects are understood as inscribed acts; in extended mind theory, minds are considered to extend beyond the body to external processes and devices. Although for different reasons, these two theories rely on the semiotic dimension to reduce the differences between minds and documents. Yet, in a certain reading, such theories are implausible if we consider that the properties of the things we call “minds” are not identical to the properties of the things we call “documents”. This calls into question a common thesis implicit in both theories: that moderate or interactionist externalism can be used to challenge strong externalism. Keywords : Law; Documents; Extended Mind; Externalism; Social Objects; Social Ontology; Maurizio Ferraris

The current Covid-19 pandemic is illustrative of both the need of more experts and of the difficulties that can arise in the face of their decisions. This happens, we argue, because experts usually interact with society through a strongly naturalistic framework, which often places experts’ epistemic authority (understood as neutrality and objectivity) at the centre, sometimes at the expenses of other pluralistic values (such as axiological ones) that people (often non-experts) cherish. In this paper, we argue that we need to supplement such a strong naturalistic framework used to promote epistemic authority with a number of virtues -both intellectual and ethical- which include i. intellectual humility, ii. courage, iii. wisdom and cares, as well as iv. relational autonomy. To illustrate this claim, we discuss these ideas in the context of the Covid-19 pandemic and analyse a set of real-life examples where important decisions have been delegated to experts merely based on their epistemic authority. We use the illustrative failures described in the case studies above-mentioned to call for a revision of current understandings of expertise (merely based on epistemic soundness). Specifically, we argue that in social contexts we increasingly need “experts in action”; that is, people with certified specialist knowledge, who can however translate it into practical suggestions, decisions, and/or public policies that are ethically more balanced and that ultimately lead to fairer, more inclusive, and more representative decisions.

Human cerebral organoids (HCOs) are three-dimensional in vitro cell cultures that mimic the developmental process and organization of the developing human brain. In just a few years this technique has produced brain models that are already being used to study diseases of the nervous system and to test treatments and drugs. Currently, HCOs consist of tens of millions of cells and have a size of a few millimeters. The greatest limitation to further development is due to their lack of vascularization. However, recent research has shown that human cerebral organoids can manifest the same electrical activity and connections between brain neurons and EEG patterns as those recorded in preterm babies. All this suggests that, in the future, HCOs may manifest an ability to experience basic sensations such as pain, therefore manifesting sentience, or even rudimentary forms of consciousness. This calls for consideration of whether cerebral organoids should be given a moral status and what limitations should be introduced to regulate research. In this article I focus particularly on the study of the emergence and mechanisms of human consciousness, i.e. one of the most complex scientific problems there are, by means of experiments on HCOs. This type of experiment raises relevant ethical issues and, as I will argue, should probably not be considered morally acceptable.

According to the thesis of powerism, our world is pervaded by causal powers which are metaphysically basic. The aim of this paper is to defend the existence of the self, defined as a substantial entity, and its mental powers. This claim, which may seem a bold one, should not be deemed as inconsistent with scientific evidence. In fact, this approach does not ignore empirical knowledge, but is not bound only to it in order to understand entities, properties, and the relationship between them. Aristotelian powerism may show that the self, as the subject of one’s mental acts, is a substance that has an essential nature. Firstly, we shall analyze the immediate evidence we have in support of the existence of the self as a substantial entity. We will show that the self is a substance because it possesses an essential character, i.e. an individual essence. We will take into account the Aristotelian perspective of substance, trying to show how the presence of a necessary property that makes every subject identical to itself and the phenomenal features of one’s private experience point to the existence of a substantial entity that corresponds to the self. Secondly, we will try to justify the adoption of a metaphysical theory of causation based on powers, analyzing it in comparison with the main competing theories, namely hypotheticalism and nomism. Then, we shall proceed to show the causal properties of the substance in question, namely the mental powers. In fact, thirdly, we will embrace the thesis of powerism by defending the existence of a set of mental powers that should be attributed to the self. We will describe the main features of mental powers and we will show that they are conceivable as the pure intentional acts we perform by directing an intentional state towards an intentional object. In this way we show how a classic problem of philosophy of mind, relevant to science as well, can be addressed in an original way by a metaphysical approach involving powers.

Many attempts have been made to explain the rise of religious phenomena based on evolutionary models, which attempt to account for the way in which religion can constitute a useful system to increase the fitness of both the individual and the group. These models implicitly mean that beliefs are simply effective adaptations to the environment and in this sense they cannot be truly accepted by those who adhere to the religions in question. In this paper, I use the evolution of culture model elaborated by Cavalli Sforza to propose an approach that can explain the change of institutionalized religions over a more limited time frame than the long times of biological evolution. This model could be heuristically effective in the study of religious phenomena and could also be applicable in terms of theology and philosophy of religion. Given the limits of space, I will only try to take a few steps in this direction, trying to answer some of the major questions that arise about such an approach. In particular, one may ask whether, unlike others, the evolution of culture model applied to religions can make it possible to put into brackets - or to remain agnostic about - the value and the truth of the beliefs and precepts of the religion which is studied.

Can transfusions of blood plasma slow down ageing or even rejuvenate people? Recent preclinical studies and experimental tests inspired by the technique known as parabiosis have aroused great media attention, although for now there is no clear evidence of their effectiveness. This line of research and the interest it is triggering testify to the prominent role played by the idea of combating the “natural” ageing process in the scientific and social agenda. While seeking to increase the duration of healthy living time may be considered a duty, it also raises ethical questions about how to pursue this goal. Specifically, therapies and techniques accessible only to a fraction of the population seem destined to exponentially increase social inequality and to produce undesirable consequences. In this article we address the issue precisely in the light of the prospected use of plasma for the rejuvenation of a small elite of people.

:The microbiome is proving to be increasingly important for human brain functioning. A series of recent studies have shown that the microbiome influences the central nervous system in various ways, and consequently acts on the psychological well-being of the individual by mediating, among others, the reactions of stress and anxiety. From a specifically neuroethical point of view, according to some scholars, the particular composition of the microbiome—qua microbial community—can have consequences on the traditional idea of human individuality. Another neuroethical aspect concerns the reception of this new knowledge in relation to clinical applications. In fact, attention to the balance of the microbiome—which includes eating behavior, the use of psychobiotics and, in the treatment of certain diseases, the use of fecal microbiota transplantation—may be limited or even prevented by a biased negative attitude. This attitude derives from a prejudice related to everything that has to do with the organic processing of food and, in general, with the human stomach and intestine: the latter have traditionally been regarded as low, dirty, contaminated and opposed to what belongs to the mind and the brain. This biased attitude can lead one to fail to adequately consider the new anthropological conceptions related to the microbiome, resulting in a state of health, both physical and psychological, inferior to what one might have by paying the right attention to the knowledge available today. Shifting from the ubiquitous high-low metaphor to an inside-outside metaphor can thus be a neuroethical strategy to achieve a new and unbiased reception of the discoveries related to the microbiome.

Nel presente testo si propone un approccio alla neuroetica che si prefigge di attribuirle uno specifico ambito d’indagine in quanto esplorazione di ciò che apprendiamo su noi stessi e sul nostro “funzionamento”, grazie principalmente alle neuroscienze. In altre parole, si tratta di un nuovo genere di antropologia che si occupa dell’intersezione di diverse discipline la quale acquista sempre maggiore centralità nel dibattito contemporaneo a motivo della forte naturalizzazione delle indagini sugli esseri umani. L’oggetto di studio – alla luce di questa particolare caratterizzazione della neuroetica – non sarà quindi ciò che possiamo fare, bensì ciò che sappiamo o riteniamo di sapere in modo affidabile.

In this paper, I use the comparison between human beings and intelligent machines to shed light on the concept of teleology. What characterizes human beings and distinguishes them from a robot capable of achieving complex objectives? In the first place, by stipulating that what characterizes human beings are mental states, I consider the mark of the mental. A smart robot probably has no consciousness but we might have reason for doubt while interacting with it. And a smart robot shows intentionality. I focus on the type of naturalized intentionality that is at stake here. Then I go back to the traditional idea of teleology, and to the scientific criticism of it, through the question of the kind of purposes that artificial intelligence (AI) may set itself. Husserl's basic idea of teleology therefore serves to have an authoritative term of comparison and to introduce the intuitive difference between human beings and intelligent machines based on the homo pictor thought experiment proposed by Jonas. My conclusion is that a specific finalism, understood in a non-criterial sense, is what qualifies the human being and differentiates the latter (for now) from smart robots.

In terms of ethical implications, Boers, van Delden and Bredenoord have made an interesting step forward with their model of organoids as hybrids, which seeks to find a balance between subject-like value and object-like value. Their framework aims to introduce effective procedures not to exploit donors and to increase their engagement, but it does not seem to take sufficient account of how organoids are used and how donors and society as a whole may want to act about such uses. I will concentrate my remarks on three points that I consider relevant. The first comment concerns the so-called mini-brains. The second one is related to the issue of consent and long-term ‘control’ over the organic material granted by donors. The last comment focuses on ‘genetic minorities’.

Non‐invasive brain stimulation is used to modulate brain excitation and inhibition and to improve cognitive functioning. The effectiveness of the enhancement due to transcranial direct current stimulation (tDCS) is still controversial, but the technique seems to have large potential for improvement and more specific applications. In particular, it has recently been used by athletes, both beginners and professionals. This paper analyses the ethical issues related to tDCS enhancement, which depend on its specific features: ease of use, immediate effect, non‐detectability and great variability of effects. If tDCS were to become widespread, there could be some potential side effects, especially the rise of inequality in many selective competitive contexts. I discuss two possible scenarios to counter this effect: that of prohibition and that of compensation, each supported by reasons and arguments that seem plausible and worthy of consideration. In conclusion, I show why I think the scenario of compensation is the preferable one.