Peter Godfrey-Smith

Is Popper's philosophy alive or dead? If we make a judgment based on recent discussion in academic philosophy of science, he definitely seems to be fading. Popper is still seen as an important historical figure, a key part of the grand drama of 20th century thinking about science. He is associated with an outlook, a mindset, and a general picture of scientific work. His name has bequeathed us an adjective, "Popperian," that is well established. But the adjective is used for very general ideas that, according to most current philosophers, Popper did not develop convincingly. His detailed account is often seen as attractive on first impression, but full of holes that become bigger rather than smaller as discussion continues. The picture and the name remain, which is more than 1 most philosophers can hope for. But the name attaches more and more to a set of instincts and intuitions, less and less to views that are seeing ongoing philosophical development. Inside science itself, Popper's standing is quite different. He continues to be just about the only philosopher who can seize the imagination and command the loyalty of successful professional scientists. And he is popular within science not only for purposes of general commentary and public relations. Popper's philosophy is a resource drawn on by scientists in their internal debates about scientific matters. This has been especially marked in some parts of biology (Hull 1999). From the point of view of philosophers, this affection on the part of scientists may have an unflattering explanation. Popper offers a rather heroic view of the scientific character, featuring an appealing combination of creativity and hard-headedness. It is no surprise that scientists like to be described this way. It is no surprise that they prefer this picture to the one often (though inaccurately) associated with Hempel and Carnap – the scientist as a sort of logic-driven pattern-recognition machine. The same applies to the picture associated with Kuhn, who presents the normal scientist as a narrow-minded, indoctrinated member of a peculiar collective enterprise, an enterprise devoted to solving tiny puzzles most of the time but prone to occasional fits of crisis and chaos..

The role played by the concept of genetic coding in biology is discussed. I argue that this concept makes a real contribution to solving a specific problem in cell biology. But attempts to make the idea of genetic coding do theoretical work elsewhere in biology, and in philosophy of biology, are probably mistaken. In particular, the concept of genetic coding should not be used (as it often is) to express a distinction between the traits of whole organisms that are coded for in the genes, and the traits that are not.

An essential introduction to the philosophy of biology This is a concise, comprehensive, and accessible introduction to the philosophy of biology written by a leading authority on the subject. Geared to philosophers, biologists, and students of both, the book provides sophisticated and innovative coverage of the central topics and many of the latest developments in the field. Emphasizing connections between biological theories and other areas of philosophy, and carefully explaining both philosophical and biological terms, Peter Godfrey-Smith discusses the relation between philosophy and science; examines the role of laws, mechanistic explanation, and idealized models in biological theories; describes evolution by natural selection; and assesses attempts to extend Darwin's mechanism to explain changes in ideas, culture, and other phenomena. Further topics include functions and teleology, individuality and organisms, species, the tree of life, and human nature. The book closes with detailed, cutting-edge treatments of the evolution of cooperation, of information in biology, and of the role of communication in living systems at all scales. Authoritative and up-to-date, this is an essential guide for anyone interested in the important philosophical issues raised by the biological sciences.

My title is intended to echo Hans Reichenbach's The Rise of Scientific Philosophy (1951), and the phrase "scientific epistemology" is intended in two Reichenbachian senses. One involves the epistemology of science; the other involves epistemology undertaken with a scientific orientation. Talk of "progress and procedures" is intended in a similar dual sense. I start by looking back over the last century, at how a family of problems was tackled by scientifically oriented philosophers. These are problems with the nature of evidence and testing – with how, given our limited access to the world and the ambitious reach of our theories, we can have good reason to believe one such theory over another. These discussions were informed especially by skeptical treatments of the problem in Hume. We see in this period a number of different theoretical strands. These are characterized by different raw materials, and by different organizing or paradigm cases – different bets regarding the parts of scientific practice that should function as exemplars.

Neyman-Pearson methods in statistics distinguish between Type I and Type II errors. Through rigid control of Type I error, the "null" hypothesis typically receives the benefit of the doubt. I compare philosophers' interpretations of this feature of Neyman-Pearson tests with interpretations given in statistics textbooks. The pragmatic view of the tests advocated by Neyman, largely rejected by philosophers, lives on in many textbooks. Birnbaum thought the pragmatic view has a useful "heuristic" role in understanding testing. I suggest that it may have the opposite effect.

How did our capacities mentally to represent the world evolve? Here is one kind of answer: To represent the world is to have a special kind of wiring inside your head, and special physical connections between that wiring and the world. How do organisms come to have that kind of wiring? Both evolution and individual learning are involved, but there has at least to be an evolutionary explanation of how some organisms acquired the capacity to wire themselves up as representers. This evolutionary story probably will be one about the usefulness of that special kind of inner wiring for dealing with environmental problems; we owe this special wiring to a long history of mutation and natural selection. Asking about the evolution of mental representation is no different form asking about the evolution of the immune system or warm-bloodedness. We might hear this first answer from people like Fred Dretske, Ruth Millikan, David Papineau, and Kim Sterelny.

One of the most striking developments in recent biology has been the proliferation of concepts such as coding, information, representation and programming, especially applied to genes. The idea that genes can be described as having semantic properties, as well as ordinary causal properties, has become so uncontroversial in many quarters that it now appears prominently in biology textbooks. Scott Gilbert's widely used developmental biology text, to pick just one example, tell us that "the inherited information needed for development and metabolism is encoded in the DNA sequences of the chromosomes" (Gilbert 1997 p. 5).

I discuss the bearing on the mind-body problem of some general characteristics of living systems, including the physical basis of metabolism and the relation between living activity and cognitive capacities in simple organisms. I then attempt to describe stages in the history of animal life important to the evolution of subjective experience. Features of the biological basis of cognition are used to criticize arguments against materialism that draw on the conceivability of a separation between mental and physical. I also argue against commonly held views about the "multiple realizability" of mental states of the kind seen in humans. The aim of the paper is to reconfigure and narrow the "explanatory gap" between mental and physical.

Methods and goals in philosophy are discussed by first describing an ideal, and then looking at how the ideal might be approached. David Lewis’s work in metaphysics is critically examined and compared to analogous work by Mackie and Carnap. Some large-scale philosophical systematic work, especially in metaphysics, is best treated as model-building, in a sense of that term that draws on the philosophy of science. Models are constructed in a way that involves deliberate simplification, or other imaginative modification of reality, in order to make relationships visible or problems tractable

John Dewey’s Experience and Nature has the potential to transform several areas of philosophy. The book is lengthy and difficult, but it has great importance for a knot of issues in epistemology, metaphysics, and philosophy of mind. It bears also on metaphilosophy, devoting many pages to the discipline’s characteristic pathologies, and advancing a view of what sort of guidance “naturalism” provides. Later chapters move on to discuss art, morality, and value. So this is a major statement by Dewey. It may one day transform moral philosophy as he hopes, but this review will focus on the central ideas of the first two-thirds of the book. Here Dewey does succeed, I think, in motivating us to look at his core topics—experience and nature—in a new way. And though Dewey’s language is often obscure and unhelpful, some of the main ideas are simpler than they look.Earlier “pragmatist” philosophical work was novel in its focus on the relation between thought and action. This work had a broadly emp

Group-structured and neighbor-structured populations are compared, especially in relation to multilevel selection theory and evolutionary transitions. I argue that purely neighborstructured populations, which can feature the evolution of altruism, are not properly described in multilevel terms. The ability to “gestalt switch” between individualist and multilevel frameworks is then linked to the investigation of “major transitions” in evolution. Some explanatory concepts are naturally linked to one framework or the other, but a full understanding is best achieved via the use of both.

The paper links discussions of two topics: biological individuality and the simplest forms of mentality. I discuss several attempts to locate the boundary between metabolic activity and ‘minimal cognition.’ I then look at differences between the kinds of individuality present in unicellular life, multicellular life in general, and animals of several kinds. Nervous systems, which are clearly relevant to cognition and subjectivity, also play an important role in the form of individuality seen in animals. The last part of the paper links these biological transitions to the evolutionary history of subjective experience.

Recent years have seen a renewed debate over the importance of groupselection, especially as it relates to the evolution of altruism. Onefeature of this debate has been disagreement over which kinds ofprocesses should be described in terms of selection at multiple levels,within and between groups. Adapting some earlier discussions, we presenta mathematical framework that can be used to explore the exactrelationships between evolutionary models that do, and those that donot, explicitly recognize biological groups as fitness-bearing entities.We show a fundamental set of mathematical equivalences between these twokinds of models, one of which applies a form of multi-level selectiontheory and the other being a form of ``individualism.'' However, we alsoargue that each type of model can have heuristic advantages over theother. Indeed, it can be positively useful to engage in a kind ofback-and-forth switching between two different perspectives on theevolutionary role of groups. So the position we defend is a``gestalt-switching pluralism.''.

The concept of information has acquired a strikingly prominent role in contemporary biology. This trend is especially marked within genetics, but it has also become important in other areas, such as evolutionary theory and developmental biology, particularly where these fields border on genetics. The most distinctive biological role for informational concepts, and the one that has generated the most discussion, is in the description of the relations between genes and the various structures and processes that genes play a role in causing. For many biologists, the causal role of genes should be understood in terms of their carrying information about their various products. That information might require the cooperation of various environmental factors before it can be "expressed," but the same can be said of other kinds of message. An initial response might be to think that this mode of description is entirely anchored in a set of well-established facts about the role of DNA and RNA within protein synthesis, summarized in the familiar chart representing the "genetic code," mapping DNA base triplets to amino acids. However, informational enthusiasm in biology predates even a rudimentary understanding of these mechanisms (Schrodinger 1944). And more importantly, current applications of informational concepts extend far beyond anything that can receive an obvious justification in terms of the familiar facts about the specification of protein molecules by DNA. This includes: 1 (i) The description of whole-organism phenotypic traits (including complex behavioral traits) as specified or coded for by information contained in the genes, (ii) The treatment of many causal processes within cells, and perhaps of the wholeorganism developmental sequence, in terms of the execution of a program stored in the genes, (iii) The idea that genes themselves, for the purpose of evolutionary theorizing, should be seen as, in some sense, "made" of information..