Charles T. Wolfe

There are many ‘idealist’ critiques of materialism, including as a natural philosophy. Early modern critiques often invoke a notion of ‘soul’ or ‘life’ as a feature which the materialist either eliminates, or at least cannot account for. Here I examine an early and powerful critique of materialism in Aristotle, which brings out both his subtlety with regard to the nature of biological entities and, perhaps, his desire to find a ‘third way’ between the pure idealism of Platonic forms and the equally pure chance-and-necessity of the atomists, who he calls the phusiologoi.

From Hegel to Engels, Sartre and Ruyer (Ruyer, Revue Philosophique 116(7–8):28–49, 1933), to name only a few, materialism is viewed as a necropolis, or the metaphysics befitting such an abode; many speak of matter’s crudeness, bruteness, coldness or stupidity. Science or scientism, on this view, reduces the living world to ‘dead matter’, ‘brutish’, ‘mechanical, lifeless matter’, thereby also stripping it of its freedom (Crocker LG, An age of crisis, Baltimore: Johns Hopkins University Press, 1959). Materialism is often wrongly presented as ‘mechanistic materialism’ – with ‘Death of Nature’ echoes of de-humanization and hostility to the Scientific Revolution (which knew nothing of materialism!), also a powerful Christian theme in Cudworth, Clarke and beyond. Here I challenge this view, by examining some ‘moments’ of radical Enlightenment materialism such as La Mettrie and Diderot (including his Encyclopédie entry “Spinosiste”), but also anonymous, clandestine texts such as L’Âme Matérielle, to emphasize their distinctive focus on the specific existence of organic beings. Second, I show how this ‘embodied’, non-mechanistic character of Enlightenment ‘vital materialism’ makes it different from other episodes, and perhaps more of an ethics than is usually thought (also via the figure of the materialist as ‘laughing philosopher’). Third, I reflect on what this implies for our image of the Enlightenment – no longer a Frankfurt School and/or Foucaldian vision of ‘discipline’, regimentation and order – but ‘vital’, without, conversely, being a kind of holist vitalism some scholars seek to oppose to materialism: vital materialism is still materialism. Its ethics tends towards hedonism, but its most radical proponents (Diderot, La Mettrie and later Sade) disagree as to what this means.

From the Enlightenment to philosophy of mind in the mid-twentieth century, two distinct trajectories can be distinguished, both of which are relevant to our story in different ways: the development of experimental neuroscience, and the gradual recognition that materialist philosophy should concern itself with the status of the brain. If classically, materialism as a thesis about the world was distinct from materialism as a brain-mind theory, some historical cases complicate that distinction, such as the debate on Locke on thinking matter. But nevertheless, it is a very operative distinction (also made by eighteenth-century critics). How do we get from that, to the ‘vulgar materialism’ of the nineteenth century (Vogt, Moleschott, but already Cabanis in 1800), with the idea of the brain secreting thought? And how, from that, to brain-mind reflections in the twentieth century? I can only suggest some pathways …

Materialism, and its approach to the body, are often presented as “mechanistic”: as signifying that the properties unique to organic, living embodied agents are reduced to or specified as mechanistically specifiable properties that characterize matter as a whole. Indeed, from Hobbes and Descartes in the seventeenth century to popular automata such as Vaucanson’s in the eighteenth century, this vision of things would seem to be correct. I aim here to correct this inaccurate vision of materialism. On the contrary, the materialist project on closer consideration reveals itself to be significantly focused on “Life” and embodiment, much more intimately connected to what we now call “vitalism” (a case in point being the eighteenth-century Montpellier vitalists), and ultimately an anti-mechanistic doctrine focusing on the uniqueness of organisms—whether we construe this focus in ontological or explanatory terms. To establish this revised vision of materialism I examine texts such as La Mettrie’s Man a Machine (1748) and Diderot’s D’Alembert’s Dream (1769) along with medical entries in the Encyclopédie by physicians such as Ménuret and Fouquet. I argue that there is a specifically materialist approach to the body in early modernity; that it is not strictly mechanistic (or is an outgrowth of a very pluralistic, loosely defined brand of mechanism), but that it retains a claim to be understood as materialist precisely because it is a reductionist, deflationary account of what it is to be in a body. This reconstruction also has implications for current discussions of embodiment: the materialist conceptualization of embodiment does not postulate an organizing center, a Subject which gives the kind of quasi-transcendental status to the flesh we often see, e.g., in phenomenological and post-phenomenological discourses.

Philosophy of biology before biology Edited by Cécilia Bognon-Küss & Charles T. Wolfe Table of contents Cécilia Bognon-Küss & Charles T. Wolfe. Introduction 1. Cécilia Bognon-Küss & Charles T. Wolfe. The idea of “philosophy of biology before biology”: a methodological provocation Part I. FORM AND DEVELOPMENT 2. Stéphane Schmitt. Buffon’s theories of generation and the changing dialectics of molds and molecules 3. Phillip Sloan. Metaphysics and “Vital” Materialism: The Gabrielle Du Châtelet Circle and French Vitalism 4. John Zammito. The Philosophical Reception of C. F. Wolff’s Epigenesis in Germany, 1770-1790: Herder, Tetens and Kant Part II. ORGANISM & ORGANIZATION 5. François Duchesneau. Senebier and the Advent of General Physiology 6. Tobias Cheung. Organization and Process. Living Systems Between Inner and Outer Worlds: Cuvier, Hufeland, Cabanis. Part III. SYSTEMS 7. Georg Toepfer. Philosophy of Ecology Long Before Ecology: Kant’s Idea of an Organized System of Organized Beings 8. Ina Goy. "All is leaf". Goethe's plant philosophy and poetry 9. Snait Gissis. ‘Biology’, Lamarck, Lamarckisms POSTSCRIPTS 1. Lynn Nyhart. A Historical Proposal Around Prepositions 2. Philippe Huneman. Philosophy after Philosophy of Biology before Biology Cécilia Bognon-Küss and Charles T. Wolfe. Conclusion

This is an introduction to a collection of articles on the conceptual history of epigenesis, from Aristotle to Harvey, Cavendish, Kant and Erasmus Darwin, moving into nineteenth-century biology with Wolff, Blumenbach and His, and onto the twentieth century and current issues, with Waddington and epigenetics. The purpose of the topical collection is to emphasize how epigenesis marks the point of intersection of a theory of biological development and a theory of active matter. We also wish to show that the concept of epigenesis existed prior to biological theorization and that it continues to permeate thinking about development in recent biological debates.

Vitalism was long viewed as the most grotesque view in biological theory: appeals to a mysterious life-force, Romantic insistence on the autonomy of life, or worse, a metaphysics of an entirely living universe. In the early twentieth century, attempts were made to present a revised, lighter version that was not weighted down by revisionary metaphysics: “organicism”. And mainstream philosophers of science criticized Driesch and Bergson’s “neovitalism” as a too-strong ontological commitment to the existence of certain entities or “forces”, over and above the system of causal relations studied by mechanistic science, rejecting the weaker form, organicism, as well. But there has been some significant scholarly “push-back” against this orthodox attitude, notably pointing to the 18th-century Montpellier vitalists to show that there are different historical forms of vitalism, including how they relate to mainstream scientific practice (Wolfe and Normandin, eds. 2013). Additionally, some trends in recent biology that run counter to genetic reductionism and the informational model of the gene present themselves as organicist (Gilbert and Sarkar 2000, Moreno and Mossio 2015). Here, we examine some cases of vitalism in the twentieth century and today, not just as a historical form but as a significant metaphysical and scientific model. We argue for vitalism’s conceptual originality without either reducing it to mainstream models of science or presenting it as an alternate model of science, by focusing on historical forms of vitalism, logical empiricist critiques thereof and the impact of synthetic biology on current (re-)theorizing of vitalism.

In this paper we examine aspects of Canguilhem’s philosophy of biology, concerning the knowledge of life and its consequences on science and vitalism. His concept of life stems from the idea of a living individual, endowed with creative subjectivity and norms, a Kantian view which “disconcerts logic”. In contrast, two different approaches ground naturalistic perspectives to explore the logic of life and the logic of the living individual in the 1970s. Although Canguilhem is closer to the second, there are divergences; for example, unlike them, he does not dismiss vitalism, often referring to it in his work and even at times describing himself as a vitalist. The reason may lie in their different views of science.

In this paper, we reflect on the connection between the notions of organism and organisation, with a specific interest in how this bears upon the issue of the reality of the organism. We do this by presenting the case of Buffon, who developed complex views about the relation between the notions of “organised” and “organic” matter. We argue that, contrary to what some interpreters have suggested, these notions are not orthogonal in his thought. Also, we argue that Buffon has a view in which organisation is not just ubiquitous, but basic and fundamental in nature, and hence also fully natural. We suggest that he can hold this view because of his anti-mathematicism. Buffon’s case is interesting, in our view, because he can regard organisation, and organisms, as perfectly natural, and can admit their reality without invoking problematic supernaturalist views, and because he allows organisation and the organismal to come in kinds and degrees. Thus, his view tries to do justice to two cautionary notes for the debate on the reality of the organism: the need for a commitment to a broadly naturalist perspective, and the need to acknowledge the interesting features of organisms through which we make sense of them.

ABSTRACT: GEORGES CANGUILHEM’S BIOPHILOSOPHY The eminent French biologist and historian of biology, François Jacob, once notoriously declared «On n’interroge plus la vie dans les laboratoires»: laboratory research no longer inquires into the notion of “Life”. Certain influential French philosophers of science of the mid‐century such as Georges Canguilhem would disagree, or at least seek to resist some of Jacob’s diagnosis. Not by imposing a different kind of research program in laboratories, but by an unusual combination of historical and philosophical inquiry into the foundations of the life sciences. Canguilhem speaks of «defending vitalist biology» and declares that Life cannot be grasped by logic. Is this history and philosophy of biology? Is it vitalism? It definitely is a different project from current philosophy of biology. One short‐lived term for it was “biophilosophy”. In this paper I explore the content of this term as it relates to the above questions.

The species of vitalism discussed here is a malleable construct, often with a poisonous reputation (but one which I want to rehabilitate), hovering in between the realms of the philosophy of biology, the history of medicine, and the scientific background of the Radical Enlightenment (case in point, the influence of vitalist medicine on Diderot). This is a more vital vitalism, or at least a more ‘biologistic,’ ‘embodied,’ medicalized vitalism. I distinguish between what I would call ‘substantival’ and ‘functional’ forms of vitalism, as applied to the eighteenth century. Substantival vitalism presupposes the existence of something like a (substantive) vital force which either plays a causal role in the natural world as studied by scientific means, or remains a kind of hovering, extra-causal entity. Functional vitalism tends to operate “post facto,” from the existence of living bodies to the desire to find explanatory models that will do justice to their uniquely ‘vital’ properties in a way that fully mechanistic models (such as Cartesian mechanism) cannot. I discuss some representative figures of the Montpellier school as being functional rather than substantival vitalists, particularly as regards the models of organic organization which they develop, and make some suggestions as to how these relate to the then-nascent science of biology.

There are books which, in the manner of a legal brief, seek to present a case by marshalling evidence around a central thesis or ‘claim’. Then there are books which are more like canvases: they assemble a wide variety of elements into a hitherto unknown or at least unseen pattern. Roy Porter’s thesis, which can be pieced together from a few half-sentences repeated at the beginning, middle and end of this book, is that there was a British Enlightenment—which was general enough that he dispenses with the need to address the question of ‘national enlightenments’, particularly the Scottish and the Irish, in this case—and that the British Enlightenment was the genuine source, or site, of the creation of ‘modernity’ or modern society, even “the birthplace of the modern” world, as his title indicates.

In this essay I seek to critically evaluate some forms of holism and organicism in biological thought, as a more deflationary echo to Gilbert and Sarkar's reflection on the need for an 'umbrella' concept to convey the new vitality of holistic concepts in biology (Gilbert and Sarkar 2000). Given that some recent discussions in theoretical biology call for an organism concept (from Moreno and Mossio’s work on organization to Kirschner et al.’s research paper in Cell, 2000, building on chemistry to articulate what they called “molecular vitalism,” studying the “vitalistic” properties of molecular, cellular, and organismal function, and Pepper and Herron’s suggestion in their 2008 paper that organisms define a category that evolutionary biology cannot do without), the question, what concept of organicism are they calling for? To what extent are such claims philosophically committed to a non-naturalistic concept of organism as organizing centre, as a foundational rather than heuristic concept – or possibly a “biochauvinism,” to use Di Paolo’s term (Di Paolo 2009)? My aim in this paper is to conceptually clarify the forms of holism and organicism that are involved in these cases (and I acknowledge that the study of early 20th-century holisms [Peterson 2010] indicates that not all of them were in fact ‘organicist’ or ‘biologistic’). I suggest that contemporary holists are still potentially beholden to a certain kind of vitalism or “biochauvinism”; but that when they reduce their claims to mere heuristics, conversely, they risk losing sight of a certain kind of organizational “thickness”, a “vital materiality” (Wheeler 2010) which is characteristic of biological systems (Bechtel 2007). And I ask if it is possible to articulate a concept of biological holism or organicism which is neither an empirical ‘biochauvinism’ nor a metaphysical ‘vitalism’?

The figure of the materialist philosopher as the « laughing philosopher », who mocks the rest of humanity, its fears, superstitions and even values, is a classic one. It has been associated variously with Democritus, Epicurus, Spinoza, Rabelais, La Mettrie and others. Apart from the interest one might have in this figure of the philosopher as someone who is rather far removed from school benches, the present essay seeks to describe or define this conceptual character in order to argue that laughter is the materialist philosopher’s « mode of access » to the human world, the so-called world of « values ». This implies that the equally classic reproach towards materialism – its coldness, its inability to grasp the dynamics of human action, what Flaubert would have called an « anatomist’s cruelty » – fails ; or only successfully targets materialism when it laughs

The organism is neither a discovery like the circulation of the blood or the glycogenic function of the liver, nor a particular biological theory like epigenesis or preformationism. It is rather a concept which plays a series of roles, sometimes masked, often normative, throughout the history of biology. Indeed, it has often been presented as a key-concept in life science and its ‘theorization’, but conversely has also been the target of influential rejections: as just an instrument of transmission for the selfish gene, but also, historiographically, as part of an outdated ‘vitalism’. Indeed, the organism, perhaps because it is experientially closer to the ‘body’ than to the ‘molecule’, is often the object of quasi-affective theoretical investments presenting it as essential, as the pivot of a science or a particular approach to nature, while other approaches reject or attack it with equal force, assimilating it to a mysterious ‘vitalist’ ontology of extra-causal forces, or other pseudo-scientific doctrines. I do not seek to adjudicate between these debates, either regarding scientific validity or historical coherence; nor do I return to the well-studied issue of the organism-mechanism tension in biology. Recent scholarship has begun to discuss the emergence and transformation of the organism concept, but has not emphasized the way the latter is a shifting, ‘go-between’ concept – invoked as ‘natural’ by some thinkers to justify their metaphysics, but then presented as value-laden by others, over and against the natural world. The organism as go-between concept is also a hybrid, a boundary concept or a limit case, which continues to function in different contexts – as a heuristic, an explanatory challenge, a model of order, of regulation, etc. – despite having frequently been pronounced irrelevant and reduced to molecules or genes. Yet this perpetuation is far removed from any ‘metaphysics of organism’, or organismic biology.

In selected texts by Diderot, including the Encyclopédie article “Cabinet d’histoire naturelle” (along with his comments in the article “Histoire nat-urelle”), the Pensées sur l’interprétation de la nature and the Salon de 1767, I examine the interplay between philosophical naturalism and the recognition of the irreducible nature of artifice, in order to arrive at a provisional definition of Diderot’s vision of Nature as “une femme qui aime à se travestir.” How can a metaphysics in which the concept of Nature has a normative status, also ultimately consider it to be something necessarily artificial? Historically, the answer to this question involves the project of natural history. A present-day reconstruction would have to make sense of this project and relate it to the vision of Nature expressed in Diderot’s phrase. In addition, it would hopefully pinpoint the difference between this brand of Enlightenment naturalism and contemporary naturalism, and by extension, allow us to understand a bit more about what naturalism is in general.

Canguilhem is known to have regretted, with some pathos, that Life no longer serves as an orienting question in our scientific activity. He also frequently insisted on a kind of uniqueness of organisms and/or living bodies – their inherent normativity, their value-production and overall their inherent difference from mere machines. In addition, Canguilhem acknowledged a major debt to the German neurologist-theoretician Kurt Goldstein, author most famously of The Structure of the Organism in 1934; along with Merleau-Ponty, Canguilhem was the main figure who introduced the work of Goldstein and his ‘phenomenology of embodiment’ into France. In this paper I inquire if we should view Canguilhem and Goldstein as ‘biochauvinists’, that is, as thinkers who consider that there is something inherently unique about biological entities as such, and if so, of what sort.