Alex Rosenberg

The underdetermination of theory by evidence must be distinguished from holism. The latter is a doctrine about the testing of scientific hypotheses; the former is a thesis about empirically adequate logically incompatible global theories or "systems of the world". The distinction is crucial for an adequate assessment of the underdetermination thesis. The paper shows how some treatments of underdetermination are vitiated by failure to observe this distinction, and identifies some necessary conditions for the existence of multiple empirically equivalent global theories. We consider how empiricists should respond to the possibility of such systems of the world

We raise three issues for Philip Kitcher's "Ethical Project" (2011): First, we argue that the genealogy of morals starts well before the advent of altruism-failures and the need to remedy them, which Kitcher dates at about 50K years ago. Second, we challenge the likelihood of long term moral progress of the sort Kitcher requires to establish objectivity while circumventing Hume's challenge to avoid trying to derive normative conclusions from positive ones--'ought' from 'is'. Third, we sketch ways in which Kitcher's metaethical opponents could respond to his arguments against them.

This paper considers whether the available evidence from archeology, biological anthropology, primatology, and comparative gene-sequencing, can test evolutionary game theory models of cooperation as historical hypotheses about the actual course of human prehistory. The examination proceeds on the assumption that cooperation is the product of cultural selection and is not a genetically encoded trait. Nevertheless, we conclude that gene sequence data may yet shed signi cant light on the evolution of cooperation

We argue that Brandon and Carson's (1996) "The Indeterministic Character of Evolutionary Theory" fails to identify any indeterminism that would require evolutionary theory to be a statistical or probabilistic theory. Specifically, we argue that (1) their demonstration of a mechanism by which quantum indeterminism might "percolate up" to the biological level is irrelevant; (2) their argument that natural selection is indeterministic because it is inextricably connected with drift fails to join the issue with determinism; and (3) their view that experimental methodology in botany assumes indeterminism is both false and incompatible with the commitment to discoverable causal mechanisms underlying biological processes. We remain convinced that the probabilism of the theory of evolution is epistemically, not ontologically, motivated

The social sciences must be biological ones, owing simply to the fact that they focus on the causes and effects of the behavior of members of a biological species, Homo sapiens. Our improved understanding of biology as a science and of the biological realm should enable us therefore to solve several of the outstanding problems of the philosophy of social science. The solution to these problems leaves most of the social and behavioral sciences pretty much as it finds them, though it does provide improved understanding of their scope, limits, and methods. Key Words: biology • natural selection • Darwinism • models • narratives • history.

This paper argues that the consensus physicalist antireductionism in the philosophy of biology cannot accommodate the research strategy or indeed the recent findings of molecular developmental biology. After describing Wolperts programmatic claims on its behalf, and recent work by Gehring and others to identify the molecular determinants of development, the paper attempts to identify the relationship between evolutionary and developmental biology by reconciling two apparently conflicting accounts of bio-function – Wrights and Nagels (as elaborated by Cummins). Finally, the paper seeks a way of defending the two central theses of physicalist antireductionism in the light of the research program of molecular developmental biology, by sharply reducing their metaphysical force.

Microeconomic theory and the theory of natural selection share salient features. This has encouraged economics to appeal to the character of evolutionary theory in defending the adequacy of microeconomics, despite its evident weaknesses as an explanatory or predictive theory. This paper explores the differences and similarities between these two theories and the phenomena they treat in order to assess the force of the economist's appeal to evolutionary theory as a model for how economic theory should proceed.

Physicalism and antireductionism are the ruling orthodoxy in the philosophy of biology. But these two theses are difficult to reconcile. Merely embracing an epistemic antireductionism will not suffice, as both reductionists and antireductionists accept that given our cognitive interests and limitations, non-molecular explanations may not be improved, corrected or grounded in molecular ones. Moreover, antireductionists themselves view their claim as a metaphysical or ontological one about the existence of facts molecular biology cannot identify, express, or explain. However, this is tantamount to a rejection of physicalism and so causes the antireductionist discomfort. In this paper we argue that vindicating physicalism requires a physicalistic account of the principle of natural selection, and we provide such an account. The most important pay-off to the account is that it provides for the very sort of autonomy from the physical that antireductionists need without threatening their commitment to physicalism

By developing an elaborate allegory, this paper attempts to show that the advertised aim of the Human Genome project, to sequence the entire 3 billion base pair primary sequence of the nucleic acid molecules that constitute the human genome, does not make scientific sense. This raises the questions of what the real aim of the project could be, and why the molecular biological community has chosen to offer the primary sequence as the objective to be funded, when identifying functionally important sub-regions of the genetic material is both far more useful and independently attainable an aim.

It is widely held that (1) there are autonomous levels of organization above that of the macromolecule and that (2) at least sometimes macromolecular processes are best explained in terms of such autonomous kinds. I argue that molecular developmental biology honors neither of these claims, and I show that the only way they can be rendered consistent with a minimal physicalism is through the adoption of controversial claims about causation and explanation which undercut the force of these two antireductionism claims

This article argues that considerations about the role and predictability of intellectual innovation make the protection of intellectual property morally obligatory even when it greatly reduces short-term welfare. Since the provision of good new ideas is the only productive input not subject to decreasing marginal productivity, welfarist considerations require that no impediment to its maximal provision be erected and the potentially substantial welfare losses imposed by a patent system be mitigated by taxation of other sources of wealth and income. Key Words: patent system • welfarism • decreasing marginal productivity.

The Routledge Companion to Philosophy of Social Science is an outstanding guide to the major themes, movements, debates, and topics in the philosophy of social science. It includes thirty-seven newly written chapters, by many of the leading scholars in the field, as well as a comprehensive introduction by the editors. Insofar as possible, the material in this volume is presented in accessible language, with an eye toward undergraduate and graduate students who may be coming to some of this material for the first time. Scholars too will appreciate this clarity, along with the chance to read about the latest advances in the discipline. The Routledge Companion to Philosophy of Social Science is broken up into four parts. Historical and Philosophical Context Concepts Debates Individual Sciences Edited by two of the leading scholars in the discipline, this volume is essential reading for anyone interested in the philosophy of social science, and its many areas of connection and overlap with key debates in the philosophy of science

That biology provides explanations is not open to doubt. But how it does so must be a vexed question for those who deny that biology embodies laws or other generalizations with the sort of explanatory force that the philosophy of science recognizes. The most common response to this problem has involved redefining law so that those grammatically general statements which biologists invoke in explanations can be counted as laws. But this terminological innovation cannot identify the source of biology's explanatory power. I argue that because biological science is historical, the problem of biological explanation can be assimilated to the parallel problem in the philosophy of history, and that the problem was solved by Carl Hempel. All we need to do is recognize that the only laws that biology—in all its compartments from the molecular onward—has or needs are the laws of natural selection.

No one has expressed the destructive power of Darwinian theory more effectively than Daniel Dennett. Others have recognized that the theory of evolution offers us a universal acid, but Dennett, bless his heart, coined the term. Many have appreciated that the mechanism of random variation and natural selection is a substrate-neutral algorithm that operates at every level of organization from the macromolecular to the mental, at every time scale from the geological epoch to the nanosecond. But it took Dennett to express the idea in a polysyllable or two. These two features of Darwinism undermine more wishful thinking about the way the world is than any other brace of notions since mechanism was vindicated in physics.

The study of economics has been a going concern among philosophers for the better part of twenty years without very many people even noticing that economics has a metaphysics. Indeed, among economists the term ‘metaphysical’ is probably an epithet of opprobrium, employed to suggest that a claim is untestable or otherwise without cognitive significance. Philosophers of economics will admit to the existence of an epistemology of economics—the study of the nature, extent and justification of economic knowledge. But even this is controversial among some economists. The notion that economics might have a metaphysics as well as an epistemology will be scoffed at by those economists doubtful about the enterprise of the philosophy of economics altogether. Nevertheless, philosophers of economics should have no trouble identifying a metaphysics in some of the theoretical commitments of economics.

The paper argues that substantial support for Soros' claims about uncertainty and reflexivity in economics and human affairs generally are provided by the operation of both factors in the biological domain to produce substantially the same processes which have been recognized by ecologists and evolutionary biologists. In particular predator prey relations have their sources in uncertainty – i.e. the random character of variations, and frequency dependent co-evolution – reflexivity. The paper argues that despite Soros' claims, intentionality is not required to produce these phenomena, and that where it does so, in the human case, it provides no basis to deny a reasonable thesis of the methodological or causal unity of science. The argument for this conclusion is developed by starting with a biological predator/prey relation and successively introducing intentional components without affecting the nature of the process. Accepting the conclusion of this argument provides substantial additional inductive support for Soros' theory in its economic application

This article argues that at least very many judgments of homology rest on prior attributions of selected‐effect (SE) function, and that many of the “parts” of biological systems that are rightly classified as homologous are constituted by (are so classified in virtue of) their consequence etiologies. We claim that SE functions are often used in the prior identification of the parts deemed to be homologous and are often used to differentiate more restricted homologous kinds within less restricted ones. In doing so, we discuss recent criticism of this view that has been offered (especially that offered by Paul Griffiths). *Received July 2007; revised November 2008. †To contact the authors, please write to: Department of Philosophy, 201 West Duke Building, Box 90743, Durham, NC 27708; e‐mail: [email protected] or [email protected].