Alex Rosenberg

The underdetermination of theory by evidence must be distinguished from holism. The latter is a doctrine about the testing of scientific hypotheses; the former is a thesis about empirically adequate logically incompatible global theories or "systems of the world". The distinction is crucial for an adequate assessment of the underdetermination thesis. The paper shows how some treatments of underdetermination are vitiated by failure to observe this distinction, and identifies some necessary conditions for the existence of multiple empirically equivalent global theories. We consider how empiricists should respond to the possibility of such systems of the world

We raise three issues for Philip Kitcher's "Ethical Project" (2011): First, we argue that the genealogy of morals starts well before the advent of altruism-failures and the need to remedy them, which Kitcher dates at about 50K years ago. Second, we challenge the likelihood of long term moral progress of the sort Kitcher requires to establish objectivity while circumventing Hume's challenge to avoid trying to derive normative conclusions from positive ones--'ought' from 'is'. Third, we sketch ways in which Kitcher's metaethical opponents could respond to his arguments against them.

An examination of the foundations of Elliot Sober's philosophy of biology as reflected in his introductory textbook of that title reveals substantial and controversial philosophical commitments. Among these are the claim that all understanding is historical, the assertion that there are biological laws but they are necessary truths, the view that the fundamental theory in biology is a narrative, and the suggestion that biology adverts to ungrounded probabilistic propensities of the sort to be met with elsewhere only in quantum mechanics.

Philosophers of biology have been absorbed by the problem of defining evolutionary fitness since Darwin made it central to biological explanation. The apparent problem is obvious. Define fitness as some biologists implicitly do, in terms of actual survival and reproduction, and the principle of natural selection turns into an empty tautology: those organisms which survive and reproduce in larger numbers, survive and reproduce in larger numbers. Accordingly, many writers have sought to provide a definition for ‘fitness’ which avoid this outcome. In particular the definition of fitness as a probabilistic propensity has been widely favored.1 Others, recognizing that no definition both correct and complete can actually be provided, have accepted the consequence that the leading principle of the theory is a definitional truth and attempted to mitigate the impact of this outcome for the empirical character of the theory.2 Still others have argued that ‘fitness’ is properly viewed as a term undefined in the theory of natural selection (on the model of mass—a term undefined in Newtonian mechanics).3 But few have contemplated the solution to this problem proposed by Mohan Matthen and André Ariew (hereafter, MA), in..

Genocentrism, the thesis that the genes play a special role in the causation of development is often rejected in favor of a 'causal democracy thesis' to the effect that all causally necessary conditions for development are equal. Genocentrists argue that genes play a distinct causal role owing to their informational content and that this content enables them to program the embryo. I show that the special causal role of the genome hinges not on its informational status — it has none, or at least no more than computer programs have independent of our interpretations of them — but on its power literally to program the embryo, a power nicely illustrated in the use of polynucleotide sequences to compute solutions to NP hard problems in mathematics

Philosophers and historians of philosophy have come to recognize that at the core of logical positivism was an attachment to prediction as the necessary condition for scientific knowledge.1 The inheritors of their tradition, especially the Bayesians among us, continue to seek a theory of confirmation that reflects this epistemic commitment. The importance of prediction in the growth of scientific knowledge is a commitment I share with the positivists, so I do not blanch at that designation, much less employ it as a term of abuse. Precisely expressing and conclusively establishing the claims of prediction as a necessary condition for certifying claims as increments of knowledge is a goal that has so far eluded us post-positivists. Philosophers know the problems well: defining a positive instance, distinguishing projectible from nonprojectible predicates, deciding whether retrodiction is as epistemically probative as prediction. 2 But I can't help thinking that these problems are technicalities - important and arresting, but not impediments to embracing the positivist demand that increments in scientific knowledge withstand tests of predictive success.

We argue that Brandon and Carson's (1996) "The Indeterministic Character of Evolutionary Theory" fails to identify any indeterminism that would require evolutionary theory to be a statistical or probabilistic theory. Specifically, we argue that (1) their demonstration of a mechanism by which quantum indeterminism might "percolate up" to the biological level is irrelevant; (2) their argument that natural selection is indeterministic because it is inextricably connected with drift fails to join the issue with determinism; and (3) their view that experimental methodology in botany assumes indeterminism is both false and incompatible with the commitment to discoverable causal mechanisms underlying biological processes. We remain convinced that the probabilism of the theory of evolution is epistemically, not ontologically, motivated

This paper considers whether the available evidence from archeology, biological anthropology, primatology, and comparative gene-sequencing, can test evolutionary game theory models of cooperation as historical hypotheses about the actual course of human prehistory. The examination proceeds on the assumption that cooperation is the product of cultural selection and is not a genetically encoded trait. Nevertheless, we conclude that gene sequence data may yet shed signi cant light on the evolution of cooperation

The social sciences must be biological ones, owing simply to the fact that they focus on the causes and effects of the behavior of members of a biological species, Homo sapiens. Our improved understanding of biology as a science and of the biological realm should enable us therefore to solve several of the outstanding problems of the philosophy of social science. The solution to these problems leaves most of the social and behavioral sciences pretty much as it finds them, though it does provide improved understanding of their scope, limits, and methods. Key Words: biology • natural selection • Darwinism • models • narratives • history.

This paper argues that the consensus physicalist antireductionism in the philosophy of biology cannot accommodate the research strategy or indeed the recent findings of molecular developmental biology. After describing Wolperts programmatic claims on its behalf, and recent work by Gehring and others to identify the molecular determinants of development, the paper attempts to identify the relationship between evolutionary and developmental biology by reconciling two apparently conflicting accounts of bio-function – Wrights and Nagels (as elaborated by Cummins). Finally, the paper seeks a way of defending the two central theses of physicalist antireductionism in the light of the research program of molecular developmental biology, by sharply reducing their metaphysical force.

Microeconomic theory and the theory of natural selection share salient features. This has encouraged economics to appeal to the character of evolutionary theory in defending the adequacy of microeconomics, despite its evident weaknesses as an explanatory or predictive theory. This paper explores the differences and similarities between these two theories and the phenomena they treat in order to assess the force of the economist's appeal to evolutionary theory as a model for how economic theory should proceed.

Physicalism and antireductionism are the ruling orthodoxy in the philosophy of biology. But these two theses are difficult to reconcile. Merely embracing an epistemic antireductionism will not suffice, as both reductionists and antireductionists accept that given our cognitive interests and limitations, non-molecular explanations may not be improved, corrected or grounded in molecular ones. Moreover, antireductionists themselves view their claim as a metaphysical or ontological one about the existence of facts molecular biology cannot identify, express, or explain. However, this is tantamount to a rejection of physicalism and so causes the antireductionist discomfort. In this paper we argue that vindicating physicalism requires a physicalistic account of the principle of natural selection, and we provide such an account. The most important pay-off to the account is that it provides for the very sort of autonomy from the physical that antireductionists need without threatening their commitment to physicalism

It is widely held that (1) there are autonomous levels of organization above that of the macromolecule and that (2) at least sometimes macromolecular processes are best explained in terms of such autonomous kinds. I argue that molecular developmental biology honors neither of these claims, and I show that the only way they can be rendered consistent with a minimal physicalism is through the adoption of controversial claims about causation and explanation which undercut the force of these two antireductionism claims

By developing an elaborate allegory, this paper attempts to show that the advertised aim of the Human Genome project, to sequence the entire 3 billion base pair primary sequence of the nucleic acid molecules that constitute the human genome, does not make scientific sense. This raises the questions of what the real aim of the project could be, and why the molecular biological community has chosen to offer the primary sequence as the objective to be funded, when identifying functionally important sub-regions of the genetic material is both far more useful and independently attainable an aim.

The Routledge Companion to Philosophy of Social Science is an outstanding guide to the major themes, movements, debates, and topics in the philosophy of social science. It includes thirty-seven newly written chapters, by many of the leading scholars in the field, as well as a comprehensive introduction by the editors. Insofar as possible, the material in this volume is presented in accessible language, with an eye toward undergraduate and graduate students who may be coming to some of this material for the first time. Scholars too will appreciate this clarity, along with the chance to read about the latest advances in the discipline. The Routledge Companion to Philosophy of Social Science is broken up into four parts. Historical and Philosophical Context Concepts Debates Individual Sciences Edited by two of the leading scholars in the discipline, this volume is essential reading for anyone interested in the philosophy of social science, and its many areas of connection and overlap with key debates in the philosophy of science

This article argues that considerations about the role and predictability of intellectual innovation make the protection of intellectual property morally obligatory even when it greatly reduces short-term welfare. Since the provision of good new ideas is the only productive input not subject to decreasing marginal productivity, welfarist considerations require that no impediment to its maximal provision be erected and the potentially substantial welfare losses imposed by a patent system be mitigated by taxation of other sources of wealth and income. Key Words: patent system • welfarism • decreasing marginal productivity.

That biology provides explanations is not open to doubt. But how it does so must be a vexed question for those who deny that biology embodies laws or other generalizations with the sort of explanatory force that the philosophy of science recognizes. The most common response to this problem has involved redefining law so that those grammatically general statements which biologists invoke in explanations can be counted as laws. But this terminological innovation cannot identify the source of biology's explanatory power. I argue that because biological science is historical, the problem of biological explanation can be assimilated to the parallel problem in the philosophy of history, and that the problem was solved by Carl Hempel. All we need to do is recognize that the only laws that biology—in all its compartments from the molecular onward—has or needs are the laws of natural selection.