•  16
    Retinoid‐regulated gene expression in normal and leukemic myeloid cells
    with William T. Moore and Michael P. Murtaugh
    Bioessays 1 (4): 160-165. 1984.
    Physiological concentrations of retinoic acid can induce acute alterations in the expression of the enzyme tissue transglutaminase in cultured macrophages. The induction of this enzyme offers a probe to study the mechanism of retinoid action in both normal and leukemic cells.
  •  3
    of a logarithmic time dependence of the fine structure constant is apparently within the limits discussed if there is a corresponding logarithmic time dependence of the strong coupling constant also. Moreover the recent discover> of naturally occurring ' Pu places the Gamow hypothesis of e' r much nearer the allov'able limits than had previously been supposed.
  •  44
    Institute of Theoretical Astronomy, University of Cambridge, Cambridge, UK 3fS. received 28th August 1970, in final revised form 1st July 1971..
  •  3
    The hypothesis that life’s rapid appearance on Earth justifies the belief that life is widespread in the universe has been investigated mathematically by Lineweaver and Davis (Astrobiol- ogy 2002;2:293–304). However, a rapid appearance could also be interpreted as evidence for a nonterrestrial origin. I attempt to quantify the relative probabilities for a non-indigenous ver- sus indigenous origin, on the assumption that biogenesis involves one or more highly im- probable steps, using a generaliz…Read more
  •  16
    Recent advances in string theory and inflationary cosmology have led to a surge of interest in the possible existence of an ensemble of cosmic regions, or “universes”, among the members of which key physical parameters, such as the masses of elementary particles and the coupling constants, might assume different values. The observed values in our cosmic region are then attributed to an observer selection effect (the so-called anthropic principle). The assemblage of universes has been dubbed “the mu…Read more
  •  81
    There have been many claims that quantum mechanics plays a key role in the origin and/or operation of biological organisms, beyond merely providing the basis for the shapes and sizes of biological molecules and their chemical affinities. These range from Schr¨odinger’s suggestion that quantum fluctuations produce mutations, to Hameroff and Penrose’s conjecture that quantum coherence in microtubules is linked to consciousness. I review some of these claims in this paper, and discuss the serious pro…Read more
  •  11
    Teachers' approaches to differentiation are described as a relationship between their planning, daily practice and thinking. Differences between the practice and thinking of teachers and implications for improving practice in differentiation are considered
  •  15
    Can Governments Improve Higher Education Through ‘Informing Choice’?
    British Journal of Educational Studies 60 (3): 261-276. 2012.
    Over the past decade higher education policy in England has gradually switched from a stance of 'government as purchaser' to 'government as informer'. During 2012 this policy stance has been intensified through new requirements for the advice provided by schools and the introduction of 'Key Information Sets' which are intended to 'drive up quality' through informed choice. This paper documents this policy shift and subjects it to critical scrutiny
  •  21
    Schooling Quasi-Markets: Reconciling Economic and Sociological Analyses
    with Nick Adnett
    British Journal of Educational Studies 47 (3). 1999.
    We provide an economic assessment of the operation of schooling quasi-markets, re-interpreting the findings of the mainly sociologically-based empirical research. We find that economic analysis is complementary to that of sociology, providing further explanations for the failure of greater competition to increase the diversity of provision and challenge traditional school hierarchies.
  •  38
    Education as a Positional Good: Implications for Market-Based Reforms of State Schooling
    with Nick Adnett
    British Journal of Educational Studies 50 (2). 2002.
    Analyses of market-based reforms of state schooling have occasionally acknowledged positional elements in parental demand, but none has fully examined their nature and implications. Contrary to the normal predictions of orthodox economic analysis, competition in positional markets can result in inefficient outcomes. Predominantly relying upon recent British experience, we examine the extent to which compulsory schooling can be viewed as a positional good and explore its implications for policy. …Read more