D. Chalmers

This chapter describes three relatively specific forms such as destructive uploading, gradual uploading, and nondestructive uploading. Neuroscience is gradually discovering various neural correlates of consciousness, but this research program largely takes the existence of consciousness for granted. It presents an argument for the pessimistic view and an argument for the optimistic view, both of which run parallel to related arguments that can be given concerning teletransportation. Cryonic technology offers the possibility of preserving our brains in a low‐temperature state shortly after death, until such time as the technology is available to reactivate the brain or perhaps to upload the information in it. Reconstructive uploading from brain scans is closely akin to ordinary (nongradual) uploading from brain scans, with the main difference being the time delay, and perhaps the continued existence in the meantime of the original person.

The easy problems of consciousness are those that seem directly susceptible to the standard methods of cognitive science, whereby a phenomenon is explained in terms of computational or neural mechanisms. The hard problems are those that seem to resist those methods. The easy problems are easy precisely because they concern the explanation of cognitive abilities and functions. Once we have specified the neural or computational mechanism that performs the function of verbal report, for example, the bulk of our work in explaining reportability is over. Baars theory of cognitive accessibility addresses many aspects of human cognition and shows promise as a theory of awareness, the functional correlate of conscious experience, but an explanation of experience itself is not on offer. The key is the conceptual point that the explanation of functions does not suffice for the explanation of experience.

This chapter provides a rich philosophical discussion of superintelligence, a widely discussed piece that has encouraged philosophers of mind to take transhumanism, mind uploading, and the singularity more seriously. It starts with the argument for a singularity: is there good reason to believe that there will be an intelligence explosion? Next, the chapter considers how to negotiate the singularity: if it is possible that there will be a singularity, how can we maximize the chances of a good outcome? Finally, it considers the place of humans in a post‐singularity world, with special attention to questions about uploading: can an uploaded human be conscious, and will uploading preserve personal identity? The chapter also analyzes whether there are certain constraints on design of artificial intelligence (AI) and AI+ that we might impose, in order to increase the chances of a good outcome.

Two-dimensional approaches to semantics, broadly understood, recognize two "dimensions" of the meaning or content of linguistic items. On these approaches, expressions and their utterances are associated with two different sorts of semantic values, which play different explanatory roles. Typically, one semantic value is associated with reference and ordinary truth-conditions, while the other is associated with the way that reference and truth-conditions depend on the external world. The second sort of semantic value is often held to play a distinctive role in analyzing matters of cognitive significance and/or context-dependence.

Frank Ramsey (1931) wrote: If two people are arguing 'if p will q?' and both are in doubt as to p, they are adding p hypothetically to their stock of knowledge and arguing on that basis about q. We can say that they are fixing their degrees of belief in q given p. Let us take the first sentence the way it is often taken, as proposing the following test for the acceptability of an indicative conditional: ‘If p then q’ is acceptable to a subject S iff, were S to accept p and consider q, S would accept q. Now consider an indicative conditional of the form (1) If p, then I believe p. Suppose that you accept p and consider ‘I believe p’. To accept p while rejecting ‘I believe p’ is tantamount to accepting the Moore-paradoxical sentence ‘p and I do not believe p’, and so is irrational. To accept p while suspending judgment about ‘I believe p’ is irrational for similar reasons. So rationality requires that if you accept p and consider ‘I believe p’, you accept ‘I believe p’.

_BMC Medical Ethics_ is an open access journal publishing original peer-reviewed research articles in relation to the ethical aspects of biomedical research and clinical practice, including professional choices and conduct, medical technologies, healthcare systems and health policies. _BMC __Medical Ethics _is part of the _BMC_ series which publishes subject-specific journals focused on the needs of individual research communities across all areas of biology and medicine. We do not make editorial decisions on the basis of the interest of a study or its likely impact. Studies must be scientifically valid; for research articles this includes a scientifically sound research question, the use of suitable methods and analysis, and following community-agreed standards relevant to the research field. Specific criteria for other article types can be found in the submission guidelines. _BMC series - open, inclusive and trusted_.

International transfers of human biological material (biospecimens) and data are increasing, and commentators are starting to raise concerns about how donor wishes are protected in such circumstances. These exchanges are generally made under contractual material transfer agreements (MTAs). This paper asks what role, if any, should research ethics committees (RECs) play in ensuring legal and ethical conduct in such exchanges. It is recommended that RECs should play a more active role in the future development of best practice MTAs involving exchange of biospecimens and data and in monitoring compliance.

The Australian HREC system is experiencing increasing workloads and greater public scrutiny. Dr Dodds asks whether the system is sustainable and aims to encourage a constructive critical debate about the system. This article suggests there is a gap between the demands on the system and expectations of researchers, regulators and the community. The evolution of the HREC system reached a significant milestone of the publication of the National Statement on Ethical Conduct in Research Involving Humans. This article argues that there will be increases in HREC workloads and new challenges from human genetic research, commercialisation of research and clinical trials. The Andrews Committee has recommended another independent review of the system. The system is also under review by the joint ALRC/ahec inquiry into the protection of human genetic information.

Amongst Professor Dickens’ extensive writings on medical law and medical jurisprudence are a host of distinguished contributions on the subject of the proper legal and ethical limits on human experimentation. As early as 1975, Professor Dickens was examining the legal aspects of human experimentation. A few years later he was promoting the responsibility of researchers to recognize and protect human rights in medical experimentation. In the last two decades, Professor Dickens has penned a rich flow of scholarly contributions on the legal and ethical rights and duties in medical experimentation and the need to do better as a research community. His articles have considered a broad range of issues in medical experimentation including the imperative of voluntary consent, the ethical unacceptability of co-ercion or inducement of research participants, embryonic research, epidemiological research and the protection of vulnerable research participants, particularly children.

Chapter 1: Two Concepts of Mind. I distinguish the phenomenal and psychological concepts of mind. I argue that every mental state is a phenomenal state, a psychological state, or a hybrid of the two. I discuss the two mind-body problems corresponding to the two concepts of mind, and discuss the various senses of the term “consciousness”. Chapter 2: Supervenience and Explanation. I distinguish varieties of supervenience, especially logical and natural supervenience, where supervening properties covary with base properties across either logically possible or naturally possible worlds. Materialism is the thesis that all positive properties globally metaphysically supervene on microphysical properties. A property is reductively explainable in terms of physical properties if it globally logically supervenes on those properties.