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126The self model and the conception of biological identity in immunologyBiology and Philosophy 21 (2): 235-252. 2006.The self/non-self model, first proposed by F.M. Burnet, has dominated immunology for 60 years now. According to this model, any foreign element will trigger an immune reaction in an organism, whereas endogenous elements will not, in normal circumstances, induce an immune reaction. In this paper we show that the self/non-self model is no longer an appropriate explanation of experimental data in immunology, and that this inadequacy may be rooted in an excessively strong metaphysical conception of …Read more
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65To Be Continued: The Genidentity of Physical and Biological ProcessesIn Thomas Pradeu & Alexandre Guay (eds.), Individuals Across The Sciences, Oxford University Press. pp. 317-347. 2016.The concept of genidentity has been proposed as a way to better understand identity through time, especially in physics and biology. The genidentity view is utterly anti-substantialist in so far as it suggests that the identity of X through time does not presuppose whatsoever the existence of a permanent “core” or “substrate” of X. Yet applications of this concept to real science have been scarce and unsatisfying. In this paper, our aim is to show that a well-defined concept of functional genide…Read more
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L'identité immunologique: soi ou continuité?L’Identité? Soi, Non-Soi, Individu Et Personne 47--58. forthcoming.
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88Immunity and the Emergence of IndividualityIn Frédéric Bouchard & Philippe Huneman (eds.), From Groups to Individuals: Evolution and Emerging Individuality, Mit Press. pp. 77. 2013.Since, it has become clear that individuality is not to be considered as a given, but rather as something which needs to be explained. How has individuality emerged through evolution, and how has it subsequently been maintained? In particular, why is it that multicellular organisms appeared and persisted, despite the obvious interest of each cell of favoring its own replication? Several biologists see the immune system as one of the key components for explaining the maintenance of multicellular …Read more
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496Toolbox murders: putting genes in their epigenetic and ecological contexts: P. Griffiths and K. Stotz: Genetics and philosophy: an introduction (review)Biology and Philosophy 31 (1): 125-142. 2016.Griffiths and Stotz’s Genetics and Philosophy: An Introduction offers a very good overview of scientific and philosophical issues raised by present-day genetics. Examining, in particular, the questions of how a “gene” should be defined and what a gene does from a causal point of view, the authors explore the different domains of the life sciences in which genetics has come to play a decisive role, from Mendelian genetics to molecular genetics, behavioural genetics, and evolution. In this review,…Read more
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Apport de la philosophie à la question de lâimmunogénicitéla Presse Médicale 39 (7): 747--752. 2010.
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13Identité, la Part de L’Autre (L'): Immunologie Et PhilosophieOdile Jacob. 2010.EN BIOLOGIE AUSSI, L'AUTRE EST EN NOUS La biologie nous montre que, dans des conditions physiologiques normales, quelque chose de l'autre est en nous. Nous avons déjà parlé de la greffe tissulaire où évidemment le tissu ou ...
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Réponse de lâauteur à la correspondance à propos de lâarticle:«Apport de la philosophie à la question de lâimmunogénicité»la Presse Médicale 40 (1): 116--117. 2011.
Thomas Pradeu
CNRS & University Of Bordeaux
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CNRS & University Of BordeauxProfessor
Areas of Specialization
Philosophy of Biology |
General Philosophy of Science |
Science, Logic, and Mathematics |