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Empirical research with Markov regime-switching models often requires the researcher not only to estimate the model but also to test for the presence of more than one regime. Despite the need for both estimation and testing, methods of estimation are better understood than are methods of testing. We bridge this gap by explaining, in detail, how to apply the newest results in the theory of regime testing, developed by Cho and White [Cho, J. S., and H. White 2007. “Testing for Regime Switching.” E…Read more
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23Standing at the Precipice: A Cautionary Note About Incremental GoodsAmerican Journal of Bioethics Neuroscience 1 (3): 46-48. 2010.
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77Drug-Induced Impulse Control Disorders: A Prospectus for Neuroethical AnalysisNeuroethics 4 (2): 91-102. 2010.There is growing evidence that dopamine replacement therapy (DRT) used to treat Parkinson’s Disease can cause compulsive behaviours and impulse control disorders (ICDs), such as pathological gambling, compulsive buying and hypersexuality. Like more familiar drug-based forms of addiction, these iatrogenic disorders can cause significant harm and distress for sufferers and their families. In some cases, people treated with DRT have lost their homes and businesses, or have been prosecuted for crimi…Read more
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25Debunking alarmist objections to the pharmacological prevention of ptsdAmerican Journal of Bioethics 7 (9). 2007.No abstract
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131Views of Addiction Neuroscientists and Clinicians on the Clinical Impact of a 'Brain Disease Model of Addiction'Neuroethics 7 (1): 19-27. 2013.Addiction is increasingly described as a “chronic and relapsing brain disease”. The potential impact of the brain disease model on the treatment of addiction or addicted individuals’ treatment behaviour remains uncertain. We conducted a qualitative study to examine: (i) the extent to which leading Australian addiction neuroscientists and clinicians accept the brain disease view of addiction; and (ii) their views on the likely impacts of this view on addicted individuals’ beliefs and behaviour. T…Read more
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120Ethical Issues Raised by Proposals to Treat Addiction Using Deep Brain StimulationNeuroethics 4 (2): 129-142. 2010.Deep brain stimulation (DBS) has been proposed as a potential treatment of drug addiction on the basis of its effects on drug self-administration in animals and on addictive behaviours in some humans treated with DBS for other psychiatric or neurological conditions. DBS is seen as a more reversible intervention than ablative neurosurgery but it is nonetheless a treatment that carries significant risks. A review of preclinical and clinical evidence for the use of DBS to treat addiction suggests t…Read more
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52Disease or Developmental Disorder: Competing Perspectives on the Neuroscience of AddictionNeuroethics 10 (1): 103-110. 2017.Lewis’ neurodevelopmental model provides a plausible alternative to the brain disease model of addiction that is a dominant perspective in the USA. We disagree with Lewis’ claim that the BDMA is unchallenged within the addiction field but we agree that it provides unduly pessimistic prospects of recovery. We question the strength of evidence for the BDMA provided by animal models and human neuroimaging studies. We endorse Lewis’ framing of addiction as a developmental process underpinned by reve…Read more
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29Avoiding Selective Ethical Objections to NudgesAmerican Journal of Bioethics 12 (2): 12-14. 2012.The American Journal of Bioethics, Volume 12, Issue 2, Page 12-14, February 2012
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23Scare-Mongering and the Anticipatory Ethics of Experimental TechnologiesAmerican Journal of Bioethics 9 (5): 47-48. 2009.
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52Public Understandings of Addiction: Where do Neurobiological Explanations Fit?Neuroethics 7 (1): 51-62. 2013.Developments in the field of neuroscience, according to its proponents, offer the prospect of an enhanced understanding and treatment of addicted persons. Consequently, its advocates consider that improving public understanding of addiction neuroscience is a desirable aim. Those critical of neuroscientific approaches, however, charge that it is a totalising, reductive perspective–one that ignores other known causes in favour of neurobiological explanations. Sociologist Nikolas Rose has argued th…Read more
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96Control and Responsibility in Addicted Individuals: What do Addiction Neuroscientists and Clinicians Think?Neuroethics 7 (2): 205-214. 2013.Impaired control over drug use is a defining characteristic of addiction in the major diagnostic systems. However there is significant debate about the extent of this impairment. This qualitative study examines the extent to which leading Australian addiction neuroscientists and clinicians believe that addicted individuals have control over their drug use and are responsible for their behaviour. One hour semi-structured interviews were conducted during 2009 and 2010 with 31 Australian addiction …Read more
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83The social implications of neurobiological explanations of resistible compulsionsAmerican Journal of Bioethics 7 (1). 2007.The authors comments on several articles on addiction. Research suggests that addicted individuals have substantial impairments in cognitive control of behavior. The authors maintain that a proper study of addiction must include a neurobiological model of addiction to draw the attention of bioethicists and addiction neurobiologists. They also state that more addiction neuroscientists like S. E. Hyman are needed as they understand the limits of their research. Accession Number: 24077921; Authors:…Read more
Clayton, Victoria, Australia