David Koepsell

This book is an easy to read, yet comprehensive introduction to practical issues in research ethics and scientific integrity. It addresses questions about what constitutes appropriate academic and scientific behaviors from the point of view of what Robert Merton called the “ethos of science.” In other words, without getting into tricky questions about the nature of the good or right (as philosophers often do), Koepsell’s concise book provides an approach to behaving according to the norms of science and academia without delving into the morass of philosophical ethics. The central thesis is that: since we know certain behaviors are necessary for science and its institutions to work properly (rather than pathologically), we can extend those principles to guide good behaviors as scientists and academics. The Spanish version of this book was commissioned by the Mexican National Science Foundation (CONACyT) and is being distributed to and used by Mexican scientists in a unique, national plan to improve scientific integrity throughout all of Mexico. Available now in English, the examples and strategies employed can be used throughout the English speaking research world for discussing issues in research ethics, training for scientists and researchers across disciplines, and those who are generally interested in ethics in academia.

Ontologies describe reality in specific domains in ways that can bridge various disciplines and languages. They allow easier access and integration of information that is collected by different groups. Ontologies are currently used in the biomedical sciences, geography, and law. A Biomedical Ethics Ontology would benefit members of ethics committees who deal with protocols and consent forms spanning numerous fields of inquiry. There already exists the Ontology for Biomedical Investigations (OBI); the proposed BMEO would interoperate with OBI, creating a powerful information tool. We define a domain ontology and begin to construct a BMEO, focused on the process of evaluating human research protocols. Finally, we show how our BMEO can have practical applications for ethics committees. This paper describes ongoing research and a strategy for its broader continuation and cooperation.

This volume considers the numerous philosophical ideas and arguments found in and inspired by the critically acclaimed series Breaking Bad. This show garnered both critical and popular attention for its portrayal of a cancer-stricken, middle-aged, middle-class, high school chemistry teacher’s drift into the dark world of selling methamphetamine to support his family. Its characters, situations, and aesthetic raise serious and familiar philosophical issues, especially related to ethics and morality. The show provokes a bevy of rich questions and discussion points, such as: What are the ethical issues surrounding drugs? What lessons about existentialism and fatalism does the show present? How does the show grapple with the concept of the end ‘justifying’ the means? Is Walt really free not to ‘break bad’? Can he be redeemed? What is the definition and nature of badness itself? Contributors address these and other questions as they dissect the legacy of the show and discuss its contributions to philosophical conversations.

"Cyberspace" is a term used commonly but without adequate definition. All computer-mediated phenomena may be said to comprise cyberspace. So far, no adequate ontology of cyberspace has been formulated. The law of intellectual property has attempted to fit computer-mediated phenomena into the current legal scheme. Currently, the law of intellectual property distinguishes between the subjects of patent law , and the subject of copyright law . The distinction embodied in the law of intellectual property is invalid and all things which are man-made and intentionally produced are expressive objects. All computer-mediated phenomena are such expressive objects. The law of intellectual property comprises a naive ontology. A common-sense ontology of intellectual property, which must abide by the rules of logic, recognizes that all man-made objects which are intentionally produced are expressive objects and should be afforded the same form on intellectual property protection. The current legal ontology has failed in devising mutually exclusive categories for objects which are of the same type, namely--expressive. A unified ontology would accommodate computer-mediated phenomena without the problems which result from the current naive ontology

The recent debate arising from leaked emails from a UK-based research group working on the issue of climate change is another in a long string of historical lapses that periodically threatens public confidence in the institutions and methods of science. As with other similar events, it did not have to happen. What should concern us is that the accepted methods and practices of science have once again to be shown to be too easily set aside, ignored, or broken due to human frailties. Years of research are now in question, publications must be viewed in a new, more skeptical light, and research programs that might have no direct relation with the one involved in the controversy are affected. One response to scandals like “ClimateGate” is to renew an oft-repeated call for increased openness in the sciences. The apparent disappearance or alteration of data, and its implications for the trustworthiness of published results of ongoing research suggests strongly that a more transparent, open, and accessible system could have prevented personal inclinations or policy concerns, even if benevolently motivated, from undermining the indifferent and detached progress of climate science

The emergence of the new information economy hascomplicated jurisdictional issues in commerce andcrime. Many of these difficulties are simplyextensions of problems that arose due to other media.Telephones and fax machines had already complicatedjurists'' determinations of applicable laws. Evenbefore the Internet, contracts were often negotiatedwithout any face-to-face contact – entirely bytelephone and fax. Where is such a contractnegotiated? The answer to this question is critical toany litigation that may arise over such contracts. Thelaws of contract are often quite different from onejurisdiction to the next.The Internet has brought with it new forms ofcommunication which make determining the loci of actseven more complicated. Where are contracts negotiatedwhen they are negotiated in cyberspace? Business isbeing conducted in chat rooms, on web sites, andthrough e-mail. Each of these is technically distinctfrom telephones and fax machines. More importantly,these tools seem ontologically different, in varyingdegrees, from traditional methods of communication.The question is, are these ontological differencessufficient to warrant new legal notions ofjurisdiction in cyberspace?Only a thorough ontological analysis of the parts ofcyberspace and acts ``in'''' it can reveal the answers tothe legal questions posed by this new medium.Traditional legal analyses have relied, in part, on acrude legal ontology. That is, courts have grappledwith notions of the topology and mereology of theworld and legal objects when considering questions ofjurisdiction. There is a simpler, theoretically soundmethod for determining legal jurisdiction which isbased upon the notion of ``purposeful direction,'''' andwhich treats computer-mediated transactions as justanother form of communication. I will explore thatmethod below.

Breaking Bad, hailed by Stephen King, Chuck Klosterman, and many others as the best of all TV dramas, tells the story of a man whose life changes because of the medical death sentence of an advanced cancer diagnosis. The show depicts his metamorphosis from inoffensive chemistry teacher to feared drug lord and remorseless killer. Driven at first by the desire to save his family from destitution, he risks losing his family altogether because of his new life of crime. In defiance of the tradition that viewers demand a TV character who never changes, Breaking Bad is all about the process of change, with each scene carrying forward the morphing of Walter White into the terrible Heisenberg. Can a person be transformed as the result of a few key life choices? Does everyone have the potential to be a ruthless criminal? How will we respond to the knowledge that we will be dead in six months? Is human life subject to laws as remorseless as chemical equations? When does injustice validate brutal retaliation? Why are drug addicts unsuitable for operating the illegal drug business? How can TV viewers remain loyal to a series where the hero becomes the villain? Does Heisenberg's Principle of Uncertainty rule our destinies? In Breaking Bad and Philosophy, a hand-picked squad of professional thinkers investigate the crimes of Walter White, showing how this story relates to the major themes of philosophy and the major life decisions facing all of us.

The age-old maxim of scientists whose work has resulted in deadly or dangerous technologies is: scientists are not to blame, but rather technologists and politicians must be morally culpable for the uses of science. As new technologies threaten not just populations but species and biospheres, scientists should reassess their moral culpability when researching fields whose impact may be catastrophic. Looking at real-world examples such as smallpox research and the Australian “mousepox trick”, and considering fictional or future technologies like Kurt Vonnegut’s “ice-nine” from Cat’s Cradle, and the “grey goo” scenario in nanotechnology, this paper suggests how ethical principles developed in biomedicine can be adjusted for science in general. An “extended moral horizon” may require looking not just to the effects of research on individual human subjects, but also to effects on humanity as a whole. Moreover, a crude utilitarian calculus can help scientists make moral decisions about which technologies to pursue and disseminate when catastrophes may result. Finally, institutions should be devised to teach these moral principles to scientists, and require moral education for future funding.

Human research ethics has developed in both theory and practice mostly from experiences in medical research. Human participants, however, are used in a much broader range of research than ethics committees oversee, including both basic and applied research at technical universities. Although mandated in the United States, the United Kingdom, Canada, and Australia, non-medical research involving humans need not receive ethics review in much of Europe, Asia, Latin America, and Africa. Our survey of the top 50 technical universities in the world shows that, where not specifically mandated by law, most technical universities do not employ ethics committees to review human studies. As the domains of basic and applied sciences expand, ethics committees are increasingly needed to guide and oversee all such research regardless of legal requirements. We offer as examples, from our experience as an ethics committee in a major European technical university, ways in which such a committee provides needed services and can help ensure more ethical studies involving humans outside the standard medical context. We provide some arguments for creating such committees, and in our supplemental article, we provide specific examples of cases and concerns that may confront technical, engineering, and design research, as well as outline the general framework we have used in creating our committee.