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21Patients’ Weighing of the Long-Term Risks and Consequences Associated With Deep Brain Stimulation in Treatment-Resistant DepressionAmerican Journal of Bioethics Neuroscience 9 (4): 243-245. 2018.
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28DBS as a ‘Technological Fix’ or a ‘Regime of Care’? Recognizing the Importance of Narrative Identity in Neurosurgical ServicesAmerican Journal of Bioethics Neuroscience 8 (3): 192-194. 2017.
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14Avoiding the Premature Introduction of Psychedelic Medicines in Alzheimer’s Disease and Related DisordersAmerican Journal of Bioethics Neuroscience 14 (2): 129-131. 2023.Peterson et al. (2023) identify two potential uses of psychedelic drugs in Alzheimer’s disease and related disorders (AD/ADRD). The first is to treat depression and anxiety that commonly occur afte...
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13Deep Brain Stimulation and Changes in “Personality”: A Catch-All with Merits and PitfallsAmerican Journal of Bioethics Neuroscience 14 (3): 320-322. 2023.The 30th anniversary of the first DBS surgery of the subthalamic nucleus (STN) for Parkinson’s disease was celebrated in Grenoble this June. Since this initial surgery, the application of DBS has e...
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21Alienation and Authenticity in Parkinson's Disease and Its TreatmentAmerican Journal of Bioethics Neuroscience 5 (4): 54-56. 2014.Why are some patients with Parkinson's disease unhappy about the outcome of deep brain stimulation (DBS)? Meccaci and Haselager (2014) attempt to answer this question by analyzing the seminal case...
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65I Miss Being Me: Phenomenological Effects of Deep Brain StimulationAmerican Journal of Bioethics Neuroscience 8 (2): 96-109. 2017.The phenomenological effects of deep brain stimulation (DBS) on the self of the patient remains poorly understood and under described in the literature, despite growing evidence that a significant number of patients experience postoperative neuropsychiatric changes. To address this lack of phenomenological evidence, we conducted in-depth, semistructured interviews with 17 patients with Parkinson's disease who had undergone DBS. Exploring the subjective character specific to patients' experience …Read more
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22Throwing the Ethics Book at Professional Organizations in the Neurological SciencesAmerican Journal of Bioethics Neuroscience 8 (4). 2017.
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26Surveillance Medicine in the DigitalEra: Lessons From Addiction TreatmentAmerican Journal of Bioethics 18 (9): 58-60. 2018.
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30Ethical, Social and Clinical Challenges in using Deep Brain Stimulation to Treat Addiction and Other Impulsive and Compulsive DisordersJahrbuch für Wissenschaft Und Ethik 19 (1): 163-188. 2015.Name der Zeitschrift: Jahrbuch für Wissenschaft und Ethik Jahrgang: 19 Heft: 1 Seiten: 163-188
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16A principle‐based framework for disclosing a psychosis risk diagnosisBioethics 37 (2): 171-182. 2022.In recent decades, researchers have attempted to prospectively identify individuals at high risk of developing psychosis in the hope of delaying or preventing psychosis onset. These psychosis risk individuals are identified as being in an ‘At-Risk Mental State’ (ARMS) through a standardised psychometric interview. However, disclosure of ARMS status has attracted criticism due to concerns about the risk–benefit ratio of disclosure to patients. Only approximately one quarter of ARMS patients devel…Read more
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19The Coercive Potential of Digital Mental HealthAmerican Journal of Bioethics 21 (7): 28-30. 2021.Digital mental health can be understood as the in situ quantification of an individual’s data from personal devices to measure human behavior in both health and disease (Huckvale, Venkatesh and Chr...
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38Drug Legalization is Not a Masterstroke for Addressing Racial InequalityAmerican Journal of Bioethics 21 (4): 44-46. 2021.Brian Earp and colleagues argue that the major harms associated with the use of illicit drugs largely arise from, or are at least exacerbated by, the fact that their use attracts criminal pe...
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17Informed Consent and Voluntariness: Balancing Ethical Demands During Trial RecruitmentAmerican Journal of Bioethics Neuroscience 12 (1): 83-85. 2021.
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17Changes in Personality Associated with Deep Brain Stimulation: a Qualitative Evaluation of Clinician PerspectivesNeuroethics 14 (1): 109-124. 2019.Gilbert et al. argue that the neuroethics literature discussing the putative effects of Deep Brain Stimulation on personality largely ignores the scientific evidence and presents distorted claims that personality change is induced by the DBS stimulation. This study contributes to the first-hand primary research on the topic exploring DBS clinicians’ views on post-DBS personality change among their patients and its underlying cause. Semi-structured interviews were conducted with sixteen clinician…Read more
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13Changes in Personality Associated with Deep Brain Stimulation: a Qualitative Evaluation of Clinician PerspectivesNeuroethics 14 (1): 109-124. 2019.Gilbert et al. argue that the neuroethics literature discussing the putative effects of Deep Brain Stimulation on personality largely ignores the scientific evidence and presents distorted claims that personality change is induced by the DBS stimulation. This study contributes to the first-hand primary research on the topic exploring DBS clinicians’ views on post-DBS personality change among their patients and its underlying cause. Semi-structured interviews were conducted with sixteen clinician…Read more
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15Beyond Flourishing: Intersecting Uses and Interests in the Neurotechnology MarketplaceAmerican Journal of Bioethics Neuroscience 10 (4): 178-180. 2019.
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24Changes in Personality Associated with Deep Brain Stimulation: a Qualitative Evaluation of Clinician PerspectivesNeuroethics 14 (1): 109-124. 2019.Gilbert et al. argue that the neuroethics literature discussing the putative effects of Deep Brain Stimulation on personality largely ignores the scientific evidence and presents distorted claims that personality change is induced by the DBS stimulation. This study contributes to the first-hand primary research on the topic exploring DBS clinicians’ views on post-DBS personality change among their patients and its underlying cause. Semi-structured interviews were conducted with sixteen clinician…Read more
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33Advancing Medicine Ethically: Important Considerations for Innovative PracticeAmerican Journal of Bioethics 19 (6): 38-40. 2019.Earl (2019) argues that the current uniform restriction of innovative practice limits clinicians’ ability to provide optimal treatment and stunts progress in medicine. We agree that it is important...
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38Deep brain stimulation of the subthalamic nucleus for the treatment of Parkinson’s disease can lead to the development of neuropsychiatric symptoms. These can include harmful changes in mood and behaviour that alienate family members and raise ethical questions about personal responsibility for actions committed under stimulation-dependent mental states. Qualitative interviews were conducted with twenty participants following subthalamic DBS at a movement disorders centre, in order to explore th…Read more
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16Of Meatballs And Invasive Neurotechnological Trials: Additional Considerations for Complex Clinical DecisionsAmerican Journal of Bioethics Neuroscience 9 (2): 100-104. 2018.Using this case, Lavazza and Reichlin (2018) explored the ethical dilemmas associated with decision making in people with Alzheimer’s disease (AD), specifically when their new preferences conflict...
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22Curing Psychopathy: Just Activate the Amygdala?American Journal of Bioethics Neuroscience 7 (3): 164-166. 2016.
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23Addiction May Not Be a Compulsive Brain Disease, But It Is More Than Purposeful Medication of Untreated Psychiatric DisordersAmerican Journal of Bioethics Neuroscience 3 (2): 54-55. 2012.
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24An Ethical Reevaluation: Where Are the Voices of Those With Anorexia Nervosa and Their Families?American Journal of Bioethics Neuroscience 6 (4): 73-74. 2015.The review by Müller and colleagues (2015) of published case studies of neurosurgical treatment of anorexia nervosa (AN) is generally sound. However, we believe that their, somewhat surprising, pro...
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22Managing Suicide Risk in Experimental Treatments of Treatment-Resistant DepressionAmerican Journal of Bioethics Neuroscience 4 (1): 38-39. 2013.
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17Justice and Equity in Trials of Deep Brain Stimulation for the Treatment of Addiction and OvereatingAmerican Journal of Bioethics Neuroscience 4 (2): 54-56. 2013.
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18Beyond the Right to Injectable HeroinAmerican Journal of Bioethics Neuroscience 1 (1): 48-49. 2010.
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15Deep Brain Stimulation in Parkinsonian Patients—Implications for Trialing DBS in Intractable Psychiatric DisordersAmerican Journal of Bioethics Neuroscience 2 (1): 14-15. 2011.
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34Ethical Guidelines for Genetic Research on Alcohol Addiction and Its ApplicationsKennedy Institute of Ethics Journal 28 (1): 1-22. 2018.The misuse of alcohol inflicts a major toll on individual users, their families, and the wider society. This includes disruptions of family life, violence, absenteeism and problems in the workplace, child neglect and abuse, and excess morbidity and mortality. The World Health Organization estimates that alcohol ranks eighth among global risk factors for death and is the third leading global risk factor for disease and disability. In the United States, alcohol dependence affects four to five perc…Read more
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Empirical research with Markov regime-switching models often requires the researcher not only to estimate the model but also to test for the presence of more than one regime. Despite the need for both estimation and testing, methods of estimation are better understood than are methods of testing. We bridge this gap by explaining, in detail, how to apply the newest results in the theory of regime testing, developed by Cho and White [Cho, J. S., and H. White 2007. “Testing for Regime Switching.” E…Read more
Clayton, Victoria, Australia