-
286Wearable Technologies for Healthy Ageing: Prospects, Challenges, and Ethical ConsiderationsJournal of Frailty and Aging 2024 1-8. 2024.Digital technologies hold promise to modernize healthcare. Such opportunity should be leveraged also to address the needs of rapidly ageing populations. Against this backdrop, this paper examines the use of wearable devices for promoting healthy ageing. Previous work has assessed the prospects of digital technologies for health promotion and disease prevention in older adults. However, to our knowledge, ours is one of the first attempts to specifically address the use of wearables for healthy ag…Read more
-
28Health Research with Big Data: Time for Systemic OversightJournal of Law, Medicine and Ethics 46 (1): 119-129. 2018.To address the ethical challenges in big data health research we propose the concept of systemic oversight. This approach is based on six defining features and aims at creating a common ground across the oversight pipeline of biomedical big data research. Current trends towards enhancing granularity of informed consent and specifying legal provisions to address informational privacy and discrimination concerns in data-driven health research are laudable. However, these solutions alone cannot hav…Read more
-
29Humanised models of cancer in molecular medicine: the experimental control of disanalogyHistory and Philosophy of the Life Sciences 33 (4). 2011.This paper explores the epistemology of extrapolation from model organisms to humans in molecular medicine. We take into account two common views on the issue, the homology view and the disanalogy view. In response to both interpretations, we argue that the foundational basis of extrapolations cannot simply be provided by homology and that relevant disanalogies can, thanks to the techniques of molecular biology, be experimentally controlled and exploited to allow useful and reliable extrapolatio…Read more
-
64Becoming partners, retaining autonomy: ethical considerations on the development of precision medicineBMC Medical Ethics 17 (1): 67. 2016.Precision medicine promises to develop diagnoses and treatments that take individual variability into account. According to most specialists, turning this promise into reality will require adapting the established framework of clinical research ethics, and paying more attention to participants’ attitudes towards sharing genotypic, phenotypic, lifestyle data and health records, and ultimately to their desire to be engaged as active partners in medical research.Notions such as participation, engag…Read more
-
31Reprogramming Potentiality: The Co-Production of Stem Cell Policy and DemocracyAmerican Journal of Bioethics 13 (1): 30-32. 2013.No abstract
-
36Disclosing Results to Genomic Research Participants: Differences That MatterAmerican Journal of Bioethics 12 (10): 20-22. 2012.The American Journal of Bioethics, Volume 12, Issue 10, Page 20-22, October 2012
-
36“Tailored-to-You”: Public Engagement and the Political Legitimation of Precision MedicinePerspectives in Biology and Medicine 59 (2): 172-188. 2016.Some patients tolerate a given drug well, without adverse reactions. For others, though, an identical dose of the same medication can have toxic effects. Moreover, while a drug can be effective at relieving symptoms for some patients, it may fail to do the same for others suffering with the same disease. With such variability in treatment responses, tailoring medical interventions to individual patients has long been an aspiration of medicine. Until recently, however, medicine lacked a clear und…Read more
-
41Genome Editing and Dialogic Responsibility: “What's in a Name?”American Journal of Bioethics 15 (12): 54-57. 2015.
-
47What mechanisms can’t do: Explanatory frameworks and the function of the p53 gene in molecular oncologyStudies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (3): 374-384. 2013.What has been called the new mechanistic philosophy conceives of mechanisms as the main providers of biological explanation. We draw on the characterization of the p53 gene in molecular oncology, to show that explaining a biological phenomenon implies instead a dynamic interaction between the mechanistic level—rendered at the appropriate degree of ontological resolution—and far more general explanatory tools that perform a fundamental epistemic role in the provision of biological explanations. W…Read more
-
20Genomic Incidental Findings: Reducing the Burden to Be FairAmerican Journal of Bioethics 13 (2): 52-54. 2013.No abstract
-
10Intentionality and the welfare of minded non-humansTeorema: International Journal of Philosophy 29 (2): 83-96. 2010.
Zürich, Canton of Zürich, Switzerland