Jin Y. Park

© 2015 The American Society of Transplantation and the American Society of Transplant Surgeons. The need to increase the donor pool for lung transplantation is a major public health issue. We previously found that administration of mesenchymal stem cells "rehabilitated" marginal donor lungs rejected for transplantation using ex vivo lung perfusion. However, the use of stem cells has some inherent limitation such as the potential for tumor formation. In the current study, we hypothesized that microvesicles, small anuclear membrane fragments constitutively released from mesenchymal stem cells, may be a good alternative to using stem cells. Using our well established ex vivo lung perfusion model, microvesicles derived from human mesenchymal stem cells increased alveolar fluid clearance in a dose-dependent manner, decreased lung weight gain following perfusion and ventilation, and improved airway and hemodynamic parameters compared to perfusion alone. Microvesicles derived from normal human lung fibroblasts as a control had no effect. Co-administration of microvesicles with anti-CD44 antibody attenuated these effects, suggesting a key role of the CD44 receptor in the internalization of the microvesicles into the injured host cell and its effect. In summary, microvesicles derived from human mesenchymal stem cells were as effective as the parent mesenchymal stem cells in rehabilitating marginal donor human lungs.

Four different instances of philosophical and religious practices in the East and in the West are presented within their own intellectual and cultural frames and then juxtaposed with discourses within and outside their traditions: Hegel's understanding of Buddhism--in his philosophy of religion--exemplifies the European rationalist metaphysical framing of the East and is re-evaluated in deconstructive terms. Pojo Chinul's hwadu meditation is situated within the development of his thought and reconsidered in the light of Soren Kierkegaard's notion of anxiety, Maurice Merleau-Ponty's concept of interrogation, and Julia Kristeva's theory of the semiotic and the symbolic. Chinul's Hwaom theory and its relation to hwadu is reinterpreted in connection with Jean-Francois Lyotard's account of modernity and the postmodern. Modern Buddhist reform agendas are juxtaposed with the role and limitations of traditional Son Buddhist thought and practice. ;By placing the concept of framing in the foreground and juxtaposing different discourses from Asia and Europe, this dissertation offers a "practice" of deconstruction and serves as "evidence" of how Western grand narratives are nearing endgame. Through its totalitarian vision of modernism, the West has assumed a privileged position in various attempts at an East-West dialogue. A new form of a dialogue in the postmodern era should reveal "differences" in perspectives, and these "differences" would not be preconditioned by value judgments from one side or the other

This chapter discusses the Huayan Buddhism of Li Tongxuan. At the core of his Buddhism is the claim that sentient beings are equipped with exactly the same qualities as the Buddha. In his analysis of the 80-fascicle version of the Huayan Jing, Li claims that Huayan teaching is a subitist teaching that proposes the awakening in this lifetime. In this context, unlike “orthodox” Huayan thinkers, Li claims that the chapter “Entering the Realm of Reality” is the core of the Huayan Jing and that Sudhana’s pilgrimage in this chapter demonstrates the importance of practice as opposed to theorization.I address these issues by examining Li’s concept of time, which I identify as “non-temporality.” In the first section, I discuss non-temporality in connection with the Buddhist themes of existence and non-existence and Li’s doctrinal classification. In the second, I address Li’s discussion of nature-arising and subitism. In the third, I discuss Li’s comparative interpretation of Sudhana in the Huayan Jing and the Dragon Girl in the Lotus Sūtra. I conclude with a consideration of the ontological and existential implications of Li’s Huayan phenomenology.

Philosophy claims that its goal is to search for truth. The history of philosophy, however, demonstrates that this search for truth has not been free from the power dynamics of respective eras. In this article, I claim that the formation of modern East Asian philosophy is one occasion in which the power structure of the time was visibly reflected. The East–West power imbalance at the beginning of the modern period was both implicitly and explicitly imbedded in the formation of modern Buddhist philosophy in East Asia. To demonstrate this point, I will examine the life and thought of two East Asian Buddhist thinkers, Paek Sŏnguk 白性郁 and Inoue Enryō 井上円了, as paradigmatic examples of...

The life and work of Kim Iryŏp (1896–1971) bear witness to Korea’s encounter with modernity. A prolific writer, Iryŏp reflected on identity and existential loneliness in her poems, short stories, and autobiographical essays. As a pioneering feminist intellectual, she dedicated herself to gender issues and understanding the changing role of women in Korean society. As an influential Buddhist nun, she examined religious teachings and strove to interpret modern human existence through a religious world view. Originally published in Korea when Iryŏp was in her sixties, Reflections of a Zen Buddhist Nun (Ŏnŭ sudoin ŭi hoesang) makes available for the first time in English a rich, intimate, and unfailingly candid source of material with which to understand modern Korea, Korean women, and Korean Buddhism. Throughout her writing, Iryŏp poses such questions as: How does one come to terms with one’s identity? What is the meaning of revolt and what are its limitations? How do we understand the different dimensions of love in the context of Buddhist teachings? What is Buddhist awakening? How do we attain it? How do we understand God and the relationship between good and evil? What is the meaning of religious practice in our time? We see through her thought and life experiences the co-existence of seemingly conflicting ideas and ideals—Christianity and Buddhism, sexual liberalism and religious celibacy, among others. In Reflections of a Zen Buddhist Nun, Iryŏp challenges readers with her creative interpretations of Buddhist doctrine and her reflections on the meaning of Buddhist practice. In the process she offers insight into a time when the ideas and contributions of women to twentieth-century Korean society and intellectual life were just beginning to emerge from the shadows, where they had been obscured in the name of modernization and nation-building.

Why and how do women engage with Buddhism and philosophy? The present volume aims to answer these questions by examining the life and philosophy of a Korean Zen Buddhist nun, Kim Iryŏp (1896–1971). The daughter of a pastor, Iryŏp began questioning Christian doctrine as a teenager. In a few years, she became increasingly involved in women’s movements in Korea, speaking against society’s control of female sexuality and demanding sexual freedom and free divorce for women. While in her late twenties, an existential turn in her thinking led Iryŏp to Buddhism; she eventually joined a monastery and went on to become a leading figure in the female monastic community until her death. After taking the tonsure, Iryŏp followed the advice of her teacher and stopped publishing for more than two decades. She returned to the world of letters in her sixties, using her strong, distinctive voice to address fundamental questions on the scope of identity, the meaning of being human, and the value of existence. In her writing, she frequently adopted an autobiographical style that combined her experiences with Buddhist teachings. Through a close analysis of Iryŏp’s story, Buddhist philosophy and practice in connection with East Asian new women’s movements, and continental philosophy, this volume offers a creative interpretation of Buddhism as both a philosophy and a religion actively engaged with lives as they are lived. It presents a fascinating narrative on how women connect with the world—whether through social issues such as gender inequality, a Buddhist worldview, or existential debates on human existence and provides readers with a new way of philosophizing that is transformative and deeply connected with everyday life. Women and Buddhist Philosophy: Engaging Zen Master Kim Iryŏp will be of primary interest to scholars and students of Buddhism, Buddhist and comparative philosophy, and gender and Korean studies.

This essay considers an ethical paradigm that can be drawn from Buddhist and postmodern philosophy. Ethics is a practical branch of philosophy and an ethical paradigm is closely connected to the fundamental structure and tenets of a philosophical system. That ethics is a practical branch of philosophy also indicates that meaning and value of a certain ethical paradigm is directly related to the environments in which the paradigm is understood and practiced. In considering an ethical paradigm based on Buddhist and postmodern philosophy, and doing so in the context of the 21st century in which we live, we will examine a paradigm I call an "ethics of tension." I will first outline the concept, and discuss how this paradigm can be a form of ethics that can be envisioned in Buddhist and postmodern philosophy. Finally, I will consider the meaning of ethics and the ethical that the ethics of tension would like to underline as an ethical discourse and for an ethical life.

This essay attempts a paradigmatic comparison between the fourfold worldview of Hua-yen Buddhism and the postmodern philosophy of Jean-François Lyotard. Employing a tension between centripetal and centrifugal forces as a structural underpinning of these two philosophies, the essay illuminates the liberating nature of Hua-yen Buddhism and postmodern thought together with the shadow of skepticism involved in endorsing a vision for a poly-lingual existence. Despite human beings' desire for a totalitarian vision hidden in every aspect of our discourse, Hua-yen Buddhism and postmodern thought demand us to envision the world of the 'inconceivable' in which the diversity of existence raises its own voice beyond the regulating force of our society

A TrajectoryIn an essay that is now a classic piece in understanding post-modern culture, Jean-François Lyotard wrote, “[e]clecticism is the degree zero of contemporary general culture: one listens to reggae, watches a western, eats McDonald’s food for lunch and local cuisine for dinner, wears Paris perfume in Tokyo and ‘retro’ clothes in Hong Kong” (Lyotard 1989: 76). The boundaries have become blurred in both positive and negative senses. Geographical borders have loosened through ever-increasing mobility as cultural exchanges become more accessible and are rapidly flowing through electronic exchanges in the cyberspace arena. Almost a quarter century after Lyotard described the present era as the time of eclecticism, the world has become more global, and the demand for cross-, inter-, and multi-cultural knowledge has become stronger than ever. In this context, globalization, cosmopolitanism, and world-citizenship have become some of the expressions with which the present time is defi.