Zhensong Wang

1. Nature has its own logic, which does not follow the human will. Nature is itself; it exists, moves, changes, and evolves according to its own intrinsic ways. Human and human society, as a product of a specific stage of natural development, can only be a concrete manifestation of the logic of nature. 2. In the broad sense, nature refers to all, both phenomena and processes, in the universe. It includes human society spiritual phenomena. In a narrow sense, nature refers to the world outside the society and opposed to society as well, or refers to the research objects of natural sciences 3. The narrow natural philosophy is in the intermediary position between the natural sciences and the overall philosophy (the supreme philosophy, an advocation of Kun Wu’s philosophy of information. For further detail, please refer to the subscript in the following.). Furthermore, it is an independent sub-level philosophical discipline; the broad natural philosophy is a meta-philosophy or supreme philosophy, stipulating the entire world from the dimensions of nature itself. 4. Natural philosophy reveals the laws of nature’s own existence, movement, change, and evolution. This determines that the way of expressing natural philosophy is necessarily natural ontology. The construction of the theoretical system of natural philosophy is inevitably a process of abandoning cognitive mediums of human beings through reflection. It is necessary for us to conclude that natural philosophy is the stipulation of nature itself, which comes out of the nature itself. So, we must explain the nature from the standpoint of the nature itself. 5. The true philosophy should move from the human world to the nature, finding back Husserl’s suspended things, and establish a brand-new philosophy in which man and nature, substance, information, and spirit are united. This kind of philosophy is able to provide contemporary ecological civilization with a reasonable philosophical foundation, rebuilding natural philosophy in a new era, which is a very urgent task for contemporary philosophers. 6. The unity of philosophy and science cannot be seen merely as an external convergence, but also as an intrinsic fusion; a true philosophy should have a scientific character, and science itself must have a philosophical basis. The unity of such an intrinsic fusion of science and philosophy can be fully demonstrated by the practical relationship of development between human philosophy and science. 7. In addition to the narrow path along epistemology, linguistics, and phenomenology, the development of human philosophy has another path. This is the development of philosophy itself that has been nurtured and demonstrated during the development of general science: On the one hand, the construction of scientific rationality requires philosophical thinking and exploration; On the other hand, the progress of science opens the way for the development of philosophy. 8. In the real process of the development of human knowledge, science and philosophy are regulated, contained, and merged with each other in the process of interaction. The two are inlaid together internally to form an interactive dynamic feedback loop. The unified relationship of mutual influence, regulation, promotion and transformation presented in the intrinsic interplay of interaction between science and philosophy profoundly breeds and demonstrates the general way of human knowledge development: the philosophicalization (a term used in Kun Wu’s philosophy of information. For more details please see in Kun Wu, 2016, The Interaction and Convergence of the Philosophy and Science of Information, https://doi.org/10.3390/philosophies1030228) of science and scientification (a term used in Kun Wu’s philosophy of information. For more detail, please see in Kun Wu, 2016, The Interaction and Convergence of the Philosophy and Science of Information, https://doi.org/10.3390/philosophies1030228) of philosophy. 9. We face two types of dogmatism: one is the dogmatism of naturalism, and the other is the dogmatism of the philosophy of consciousness. One of the best ways to overcome these tendencies of dogmatism is to unite natural ontology, and epistemic constructivism. The crisis of contemporary philosophy induced by the western consciousness philosophy seems like belonging to the field of epistemology, but the root of this crisis is deeply buried in the ontology. The key to solving the crisis of contemporary philosophy lies precisely in the reconstruction of the doctrine of natural philosophy centering to the nature itself and excluding God. The task to be accomplished by this new natural philosophy is how to regain the natural foundation of human consciousness after the God has left the field. 10. Since the 1980s, the philosophy of information established and developed in China has proposed a theory of objective information, as well as the dual existence and dual evolution of matter and information (a key advocation in the ontological theory of Kun Wu’s philosophy of information). It is this theory that has made up for the vacancy existing between matter and mind, which apparently exists in Cartesian dualism, after the withdrawal of the God’s from the field. Philosophy of information in China is first and foremost a natural philosophy that adheres to naturalistic attitudes. Second, this natural philosophy explains the human, human mind and human society in the interpretation of the process and mechanism of natural evolution. In this connection, philosophy of information (a key advocation of Kun Wu’s philosophy of information) in China is a system of meta-philosophy or supreme philosophy. This system undoubtedly has the nature of a new natural philosophy. At the same time, this philosophy can better reflect the philosophical spirit of the information age.

© 2014 Nature America, Inc. All rights reserved. Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated 1/42,000, 1/43,700 and 1/49,500 SNPs explained 1/421%, 1/424% and 1/429% of phenotypic variance. Furthermore, all common variants together captured 60% of heritability. The 697 variants clustered in 423 loci were enriched for genes, pathways and tissue types known to be involved in growth and together implicated genes and pathways not highlighted in earlier efforts, such as signaling by fibroblast growth factors, WNT/I 2-catenin and chondroitin sulfate-related genes. We identified several genes and pathways not previously connected with human skeletal growth, including mTOR, osteoglycin and binding of hyaluronic acid. Our results indicate a genetic architecture for human height that is characterized by a very large but finite number of causal variants.