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23The Role, Remit and Function of the Research Ethics Committee — 4. Limits to Consent?Research Ethics 6 (4): 159-163. 2010.This is the fourth in a series of five papers on the role, remit and function of research ethics committees which are intended to provide for REC members a broad understanding of the most important issues in research ethics and governance. This paper explores the role of ethics committees in reviewing proposed conditions for recruiting human subjects and in checking the intended procedures for gaining consent. In so doing the paper will reiterate the conditions which are traditionally thought to…Read more
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21The Role, Remit and Function of the Research Ethics Committee — 1. The Rationale for Ethics Review of Research by CommitteeResearch Ethics 5 (4): 147-150. 2009.This is the first in a series of five papers on the role, remit and function of research ethics committees which are intended to provide for REC members a broad understanding of the most important issues in research ethics and governance. The first considers the rationale for having ethics review by committee at all; seeking to explain why ethics committees, as we currently have them, are so important to the wider system of governing research.
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19Inequalities and Fairness in Cluster TrialsResearch Ethics 7 (2): 58-65. 2011.Cluster randomized controlled trials (cluster RCTs) randomize whole clusters of individuals in testing two or more competing interventions. Here we will present the ethical problems raised by cluster RCTs concerning their effect on inequality. We argue that some inequalities generated by cluster RCTs are larger in scope than those generated from individual RCTs. We also argue that any cluster RCT-generated inequalities, which divide groups rather than individuals, are more problematic in type th…Read more
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19Ethics of Clinical Science in a Public Health Emergency: Drug Discovery at the BedsideAmerican Journal of Bioethics 13 (9): 3-14. 2013.Clinical research under the usual regulatory constraints may be difficult or even impossible in a public health emergency. Regulators must seek to strike a good balance in granting as wide therapeutic access to new drugs as possible at the same time as gathering sound evidence of safety and effectiveness. To inform current policy, I reexamine the philosophical rationale for restricting new medicines to clinical trials, at any stage and for any population of patients (which resides in the precaut…Read more
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19Response to Open Peer Commentaries on “Ethics of Clinical Science in a Public Health Emergency: Drug Discovery at the Bedside”American Journal of Bioethics 13 (9). 2013.No abstract
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18Rationing, randomising, and researching in health care provisionJournal of Medical Ethics 28 (1): 20-23. 2002.In this paper the need for valid evidence of the cost-effectiveness of treatments that have not been properly evaluated, yet are already available, albeit in short supply, are examined. Such treatments cannot be withdrawn, pending proper evaluation, nor can they be made more widely available until they have been shown to be cost-effective. As a solution to this impasse the argument put forward recently by Toroyan et al is discussed. They say that randomised controlled trials of such resources co…Read more
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17Protecting privacy interests in brain images : the limits of consentIn Sarah Richmond, Geraint Rees & Sarah J. L. Edwards (eds.), I know what you're thinking: brain imaging and mental privacy, Oxford University Press. 2012.
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16Recognising values and engaging communities across cultures: towards developing a cultural protocol for researchersBMC Medical Ethics 22 (1): 1-8. 2021.Efforts to build research capacity and capability in low and middle income countries (LMIC) has progressed over the last three decades, yet it confronts many challenges including issues with communicating or even negotiating across different cultures. Implementing global research requires a broader understanding of community engagement and participatory research approaches. There is a considerable amount of guidance available on community engagement in clinical trials, especially for studies for…Read more
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16The Ottawa statement on the ethical design and conduct of cluster randomized trials: A short reportResearch Ethics 11 (1): 52-60. 2015.Owing to unique features of their design, cluster randomized trials complicate the interpretation of standard ethics guidelines. The recently published Ottawa statement on the ethical design and conduct of cluster randomized trials provides researchers and research ethics committees with detailed guidance on the design, conduct, and review of cluster trials. The Ottawa statement sets out 15 recommendations, including guidance on the justification of study design, the need for research ethics com…Read more
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14Governing taste: data, temporality and everyday kiwifruit dry matter performancesAgriculture and Human Values 40 (2): 519-531. 2022.Data is essential to governing those emerging matters of concern that confront the agrifood every day. But data is no neutral intermediary. It disrupts, exposes, and creates new social, economic, political, and environmental possibilities, whilst simultaneously hiding, excluding, and foreclosing others. Scholars have become attuned to both the constitutive role of data in creating everyday worlds, and the need to develop critical accounts of the materialities, spatialities and multiplicities of …Read more
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13Editorial: the unexpected power of research ethicsResearch Ethics 16 (1-2): 1-3. 2020.Research Ethics, Ahead of Print.
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10The Role, Remit and Function of the Research Ethics Committee — 2. Science and Society: The Scope of Ethics ReviewResearch Ethics 6 (2): 58-61. 2010.This is the second in a series of five papers on the role, remit and function of research ethics committees which are intended to provide for REC members a broad understanding of the most important issues in research ethics and governance. This paper examines the role of ethics committees in assessing the science of the research it reviews. While ethics committees are not specifically constituted to review the science of a project, they must nevertheless assess the social benefits of research an…Read more
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10Limitations to Contingency Measures: Reflections from COVID-19 Surges in the UKAmerican Journal of Bioethics 21 (8): 31-34. 2021.Alfandre et al. helpfully outlines the case for attending to contingency planning as well as to crisis measures during a pandemic. The authors provides a helpful framework for reflecting on...
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8An ethics of anthropology‐informed community engagement with COVID‐19 clinical trials in AfricaDeveloping World Bioethics 23 (3): 242-251. 2023.The COVID‐19 pandemic has reinforced the critical role of ethics and community engagement in designing and conducting clinical research during infectious disease outbreaks where no vaccine or treatment already exists. In reviewing current practices across Africa, we distinguish between three distinct roles for community engagement in clinical research that are often conflated: 1) the importance of community engagement for identifying and honouring cultural sensitivities; 2) the importance of rec…Read more
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4Editorial: Continuous consent to, or discreet control over, sharing digital data?Research Ethics 10 (4): 184-186. 2014.
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ConclusionIn Sarah Richmond, Geraint Rees & Sarah J. L. Edwards (eds.), I know what you're thinking: brain imaging and mental privacy, Oxford University Press. 2012.