Hub Zwart

Michael Crichton‟s latest novel Next (2006) is his third about genomics. Yet, whereas Jurassic Park (and its sequel The lost world) contained stories about sequencing, reconstructing and revivifying the genomes of (extinct) animals, Next analyses the impact of genomics in the biomedical sphere: its consequences for human life (health, labour, sexuality, family life). Gene patenting, and the philosophy of genetic determinism that inspired and legitimised this practice, is at the root of most of the soap-like absurdities Crichton stages in his novel.

When the Human Genome Project (HGP) was launched, our genome was presented as our ‘blueprint’, a metaphor reflecting a genetic deterministic epistemology. Eventually, however, the HGP undermined rather than strengthened the understanding of genomes as blueprints and of genes as ultimate causal units. A symbolical turning point was the discovery that the human genome only contains 22,500 genes. Initially, this was seen as a narcissistic offence. Gradually, however, it strengthened the shift from traditional genetics and biotechnology (i.e., gene-oriented approaches) to genomics, i.e. genome-oriented or systems approaches, emphasizing complexity. The 20th century can be regarded as the century of biotechnology and of the gene. Its history demonstrated that the will to know (notably: to know ourselves) has never been a disinterested affair: it is driven by a will to improve (notably: to improve ourselves). In this article it is claimed that, as genomics takes us beyond a genetic deterministic understanding of life, this must have consequences for societal research and debate as well. Policies for self-improvement will increasingly rely on the use of complex interpretation. Therefore, the emphasis must shift from issues such as genetic manipulation and human enhancement to issues involved in governance of novel forms of information.

Although he died in 2008, prolific science novelist Michael Crichton – acting as a ‘ghost-writer’, so to speak – continues to add new titles to his oeuvre. Notwithstanding the death of the author, his novel-producing machinery refuses to come to a full stop, - although in this case Richard Preston (a science novelist in his own right, author of, among others, The Hot Zone, on viral infections) was recruited to finish the book. MICRO – a title that almost reads like the acronym of the author’s name - has all the ingredients of the standard Michael Crichton formula.

In contemporary bioethics, two vocabularies can be distinguished:person-speak andnature-speak. The first is built around the claim that a person's moral decisions are to be respected, while the other stands on the claim that moral decisions should comply with standards for human behaviour conveyed by nature. While most bioethicists have obtained a thorough mastery ofperson-speak, they are considerably less well-versed innature-speak. Apparently, the latter has lost much of its former ability to capture important aspects of moral existence. In this paper I attempt to rehabilitatenature-speak from a hermeneutical perspective. I believe that the task of ethics is to enlarge our range of moral description and to rediscover neglected ways of speaking about human experience. The ethicist should enable individuals in health care settings to become more articulate about their moral experience. He should not content himself with applying those moral vocabularies which happen to be readily available, but should rather proceed by recovering forgotten vocabularies from within the philosophical tradition. Finally, one particular effort at restoringnature-speak is critically reviewed

There are basically two ways of teaching philosophy to science stu- dents. One option is to start from philosophy (from Plato and Aristotle up to, say, Popper and Kuhn) and present student audiences with the ideas and conjectures of these “great thinkers,” these “authoritative voices,” concerning scientific inquiry: the top-down approach. Another option is to trawl the archives of science (of present and past) search- ing for philosophical quandaries, moral collisions and paradigm shifts, for intriguing case studies that contain important lessons for science students of today: the bottom-up approach. Various intermediate forms (combinations of both approaches) are possible of course. I myself tend to opt for the bottom-up approach, since it involves dialogue with and proximity to science. It is in the folds and margins of scientific dis- course that some of the most challenging philosophical issues of today emerge. I regard this approach as mutual learning, moreover: probing philosophical issues through trans-disciplinary dialogue and team work.

Drama is a relatively unexplored tool in academic science education. This paper addresses in what way the use of drama may allow science students to deepen their understanding of recent developments in the emerging and controversial field of neuro-enhancement, by means of a case study approach. First, we emphasise the congruency between drama and science, notably the dramatic dimension of experimental research. Subsequently, we draw on educational literature to elaborate the potential of using drama as a teaching modality, specifically focusing on the ethical and moral dimensions of future techno-scientific innovations. Our case study consisted of a drama experiment as a module in a philosophy course on human enhancement. Twenty-two students from various science disciplines performed multiple roles, as authors, actors, audience and reviewers. Qualitative data were collected on the educational process and student performance during the course, i.e. observations and video recordings of class discussions, group work and plays, interviews and questionnaires. Our drama experiment proved to be effective in enabling students to explore and relate to a future life world affected by enhancement technologies. It allowed them to deepen their awareness of social and ethical implications of neuro-technologies and of the different viewpoints people may have on this issue in academic, professional or everyday settings. Moreover, drama allowed them to develop a reflexive position of their own in the neuro-enhancement debate by enacting a moral dilemma in front of an audience. Our results confirm the potential of drama as a tool for exploring techno-scientific futures in science education.

The Biblical story of the Art (a floating, zoo-like device, constructed to survive climate turmoil and mass extinction) can be regarded as an archetypal image (in the terminology of Gaston Bachelard), capturing structural components of the human-animal relationship. Building on the contributions by Larson and Barr, Keulartz, Bovenkerk and Verweij, and Ramp and Bekoff, I will argue that, in the course of history, the Ark has evolved from a fictional (imaginary) icon into something increasingly real. The agricultural village of the Neolithic era already functioned as a sheltered enclave, a survival machine designed to allow a select number of humans and accompanying species to withstand environmental fluctuations and survival pressure. In the current situation, however, the Ark has developed into a Gestell of planetary dimensions. The concept of the anthropocene basically conveys the idea that we have entered a global symbolical Ark, conceptualised by Teilhard de Chardin as the noosphere (the world-wide web of intelligence and policies, technologies and engineering, research and regulations) and emerging against the backdrop of a necro(s)cene: an ambiance of mass extinction. Increasingly, prospects for survival of a disconcertingly large number of species depend on human behaviour and human decision: on our ability or failure to collectively address the daunting challenges of the present.

Ten years after introducing the RRI concept, a reflection on its key ambitions seems called for, now that RRI enters the global arena. This paper focues on the key challenge that RRI is currently facing: epistemic inclusion. From the beginning, there has been the awareness that RRI must be open to multiple voices and perspectives, coming from academia, and also from society at large. Besides representing impressive bodies of knowledge, academic disciplines face knowledge gaps as well and must reach out to other knowledge forms, e.g. practical, experiential, and indigenous knowledge. This paper analyses the challenges involved in epistemic inclusion while outlining viable pathways towards addressing them, based on experiences in European projects as our ‘laboratory'. After discussing interdisciplinarity, participatory research, and epistemic pluralism, while also addressing the academic reward system. Special attention is given to indigenous knowledge as a case study for epistemic pluralism.

Much has been said about the need for improving the current definitions of scientific authorship, but an aspect that is often overlooked is how to formulate and communicate these definitions to ensure that they are comprehensible and useful for researchers, notably researchers active in international research consortia. In light of a rapid increase in international collaborations within natural sciences, this article uses authorship of this branch of sciences as an example and provides suggestions to improve the comprehensibility of the definitions of authorship in natural sciences. It assesses whether the definition of authorship provided by the European Code of Conduct for Research Integrity can deal with current issues and problems of scientific authorship. Notably, problems that are experienced in project groups with researchers coming from multiple countries. Using theories developed by Jürgen Habermas and Robert Merton, a normative framework is developed to articulate ethical authorship in natural sciences. Accordingly, enriching the current definition of authorship with normative elements and using discipline-specific metaphors to communicate them are introduced as possible ways of improving the comprehensibility of the definition of authorship in international environments. Finally, this article provides a proposal to be considered in the future revisions of the European Code of Conduct for Research Integrity.

This article explores the impact of an Increase in the average Number of Authors per Publication on known ethical issues of authorship. For this purpose, the ten most common ethical issues associated with scholarly authorship are used to set up a taxonomy of existing issues and raise awareness among the community to take precautionary measures and adopt best practices to minimize the negative impact of INAP. We confirm that intense international, interdisciplinary and complex collaborations are necessary, and INAP is an expression of this trend. However, perverse incentives aimed to increase institutional and personal publication counts and egregious instances of guest or honorary authorship are problematic. We argue that whether INAP is due to increased complexity and scale of science, perverse incentives or undeserved authorship, it could negatively affect known ethical issues of authorship at some level. In the long run, INAP depreciates the value of authorship status and may disproportionately impact junior researchers and those who contribute to technical and routine tasks. We provide two suggestions that could reduce the long-term impact of INAP on the reward system of science. First, we suggest further refinement of the CRediT taxonomy including better integration into current systems of attribution and acknowledgement, and better harmony with major authorship guidelines such as those suggested by the ICMJE. Second, we propose adjustments to the academic recognition and promotion systems at an institutional level as well as the introduction of best practices.

In Seminar XVII, entitled The reverse side of psychoanalysis, Jacques Lacan presents his famous theorem of the four discourses. In this rereading I propose to demonstrate that Lacan’s theorem entails a transferable dialectical method for studying processes of knowledge production, enabling contemporary scholars to develop a diagnostic of the present, notably scholars interested in issues such as the vicissitudes of knowledge production under capitalism, the crisis of the university and the proliferation of electronic gadgets. In short, I will argue that Lacan’s theorem of the four discourses entails a dialectical diagnostic of technoscientific knowledge during late capitalism. First, the four discourses will be briefly outlined, emphasising the extent to which they entail, albeit in an ambivalent manner, a return or detour to the logic of Hegel. Subsequently, each discourse will be presented in more detail, emphasising how they allow us to come to terms with the current status of technoscientific knowledge. Special attention will be given to the political backdrop of the seminar: the crisis of the university. Finally, I will discuss the historical dimension, outlining both the predecessor of the four discourses and their current predicament under neoliberal/capitalist conditions.

This article addresses the question whether and how literary documents can be used to further our understanding of a number of key issues on the agenda of the philosophy of biology such as “complexity” and “reductionism”. Kant already granted a certain respectability to aesthetical experiences of nature in his third Critique. Subsequently, the philosophical movement known as phenomenology often used literary sources and literary techniques to criticize and question mainstream laboratory science. The article discusses a number of literary documents, from Moby-Dick to Jurassic Park, that explicitly stage a confrontation between scientific and non-scientific ways of experiencing and understanding the natural world. Special attention is given to the work of Michael Crichton. Its relevance for the philosophy of biology is pointed out.

In this paper, we present a Lacanian perspective on football, while notably fathoming its normative dimension. Starting with a defining imperative, the prohibition against ‘handling’ or touching the ball with your hands, diverging football historically from rugby, we will subsequently focus our attention on the role of the foot, the eye (notably the eyes of the audience) and the ‘object a’ (in the context of gender). Against this backdrop, we will address pressing issues such as the troubled position of the referee (as an ‘impossible profession’), the commercialisation of football, and the rising tides of violence, match—fixing and other instances of systemic deviance. As we will argue, football exemplifies modern sport as an arena defined by prohibitions and desire, by inclusion and exclusion, by purity and abuse, culminating in recent challenges involved in gender trouble. Symbolical practices, like modern football, are based on in- and exclusion. Instead of more regulations and dichotomies, we advocate careful attention to the delicate art of handling desire in practice.

The key objective of this volume is to allow philosophy students and early-stage researchers to become practicing philosophers in technoscientific settings. Zwart focuses on the methodological issue of how to practice continental philosophy of technoscience today. This text draws upon continental authors such as Hegel, Engels, Heidegger, Bachelard and Lacan in developing a coherent message around the technicity of science or rather, “technoscience”. Within technoscience, the focus will be on recent developments in life sciences research, such as genomics, post-genomics, synthetic biology and global ecology. This book uniquely presents continental perspectives that tend to be underrepresented in mainstream philosophy of science, yet entail crucial insights for coming to terms with technoscience as it is evolving on a global scale today. This is an open access book.

Throughout the 20th century, philosophers have criticized the scientific understanding of the human body. Instead of presenting the body as a meaningful unity or Gestalt, it is regarded as a complex mechanism and described in quasi-mechanistic terms. In a phenomenological approach, a more intimate experience of the body is presented. This approach, however, is questioned by Jacques Lacan. According to Lacan, three basic possibilities of experiencing the body are to be distinguished: the symbolical (or scientific) body, the imaginary (or ideal) body and the real body. Whereas the symbolical body is increasingly objectified (and even digitalized) by medical science, the phenomenological perception amounts to an idealization of the body. The real body cannot be perceived immediately. Rather, it emerges in the folds and margins of our efforts to symbolize or idealize the body, which are bound to remain incomplete and fragile. In the first part of the article (§1-§3), Lacan's conceptual distinction between the symbolical, the imaginary and the real body will be explained. In the second part (§4-§5), this distinction will be further clarified by relying on crucial chapters in the history of anatomy (notably Mundinus, Vesalius, Da Vinci and Descartes).

This paper develops a dialectical methodology for assessing technoscience during the Anthropocene. How to practice Hegelian dialectics of technoscience today? First of all, dialectics is developed here in close interaction with contemporary technoscientific research endeavours, which are addressed from a position of proximity and from an ‘oblique’ perspective. Contrary to empirical research, the focus is on how basic concepts of life, nature and technology are acted out in practice. Notably, this paper zooms in on a synthetic cell project called BaSyC as a concrete instantiation of converging views of life, nature and technology currently at work in technoscience. While dialectics is used to explore the significance of this project, the synthetic cell as a case study also allows us to demonstrate the remarkable relevance of dialectics for understanding contemporary research, notably because it incites us to see the synthetic cell project as a concrete exemplification of life under Anthropocenic conditions. Should we assess the synthetic cell as the ultimate realisation of the technoscientific will to control and optimise life, or rather as an effort to bridge the disruptive collision between technoscience and nature, or both?

A Life Decoded is an exhilarating document, to begin with, reading like a novel or even a science epic. In the author’s own words, it is “a tale of seemingly impossible quests and grand objectives”, of “great rivalries and bitter disputes”, of “battles of ideologies, morals and ethics” and of “clashes of egos” (p. 2), an adventure that swept the author “from peaks of incredible exhilaration as I marshaled a relatively small but dedicated army of scientists, computers and robots to achieve what seemed almost impossible, and then plunged me into black pits of depression as I faced opposition from Nobel laureates and senior government officials, my colleagues, and even my wife” (p. 2). Moreover, besides being an autobiography proper, the book also contains a series of reflections on the genes present in the author’s own genome, one of the first individual genomes that was sequenced and made publicly available on the web – the “recipe” that made Craig Venter, as he himself describes it. In separate boxes dedicated to his sequenced genome, he especially focuses on genes that are associated with behavioural characteristics such as thrill-seeking behaviour, ADHD and the ability to cope with almost superhuman amounts of stress. Thus, in Venter’s case, autobiography and the genome are connected in more than one way with one another.

We participate in moral debate, instead of taking morality for granted, because of discontent with the moral discourse in vogue. We feel that something is distorted or concealed. One way to expose deficiencies in established discourse is critical argument, but under certain specific historical circumstances, the apparent self-evidence of established moral discourse has gained such a sway, has acquired such an ability to conceal its basic vulnerability, that its validity seems beyond contestation. Then, all of a sudden, its vulnerability is revealed, through the experience of laughter. Moral criticism is preceded by laughter. All crucial transformations in the history of moral thinking were made possible by laughter and moral criticism is originally a comic genre. The moral significance of laughter is recovered with the help of four philosophers of laughter: Bakhtin, Nietzsche, Bataille and Foucault. Laughter allows reality to appear in a certain light. It is a philosophical factor in its own right. This is explained through a thorough analysis of three crucial moral revolutions occurring in the fourth century B.C., the sixteenth century A.D. and the nineteenth century A.D. These transformations involved basic experiences of laughter articulated by three outstanding protagonists, namely Socrates, Luther and Ibsen.

This paper considers Bram Stoker’s novel Dracula, published in 1897, as a window into techno-scientific and sociocultural developments of the fin-de-siècle era, ranging from blood transfusion and virology up to communication technology and brain research, with a particular focus on the birth of psychoanalysis. Stoker’s literary classic heralds a new style of scientific thinking, foreshadowing important aspects of post-1900 culture. Dracula reflects a number of scientific events which surfaced in the 1890s and evolved into major research areas that are still relevant today. Rather than seeing science and literature as separate realms, Stoker’s masterpiece encourages us to address the ways in which techno-scientific and psycho-cultural developments mutually challenge and mirror one another, so that we may use his novel to deepen our understanding of emerging research practices and vice versa. Psychoanalysis plays a double role in this. It is the research field whose genealogical constellation is being studied, but at the same time psychoanalysis guides my reading strategy. Dracula, the infectious, undead Vampire has become an archetypal cinematic icon and has attracted the attention of numerous scholars. The vampire complex built on various folkloristic and literary sources and culminated in two famous nineteenth-century literary publications: the story The Vampyre by John Polidori and Stoker’s version. Most of the more than 200 vampire movies released since Nosferatu are based on the latter. Rather than focus on the archetypal cinematic image of the Vampire, I discuss the various scientific ideas and instruments employed by Dracula’s antagonists to overcome the threat to civilisation he represents.