Aliesha Kumar

© 2014. The Authors.The global characteristics of tropical cyclones simulated by several climate models are analyzed and compared with observations. The global climate models were forced by the same sea surface temperature fields in two types of experiments, using climatological SST and interannually varying SST. TC tracks and intensities are derived from each model's output fields by the group who ran that model, using their own preferred tracking scheme; the study considers the combination of model and tracking scheme as a single modeling system, and compares the properties derived from the different systems. Overall, the observed geographic distribution of global TC frequency was reasonably well reproduced. As expected, with the exception of one model, intensities of the simulated TC were lower than in observations, to a degree that varies considerably across models. Key Points: Multimodel comparison of tropical cyclone activity in global climate models Geographic distribution of the TC activity is similar to observed Most models produce tropical cyclones weaker than observed.

Fragile X premutation carriers are characterized by 55-200 CGG trinucleotide repeats in the 5' untranslated region on the Xq27.3 site of the X chromosome. Clinically, they are associated with the fragile X-Associated Tremor/Ataxia Syndrome, a late-onset neurodegenerative disorder with diffuse white matter neuropathology. Here, we conducted first-ever graph theoretical network analyses in fXPCs using 30-direction diffusion-weighted magnetic resonance images acquired from 42 healthy controls aged 18-44 years and 46 fXPCs. Globally, we found no differences between the fXPCs and HCs within each gender for all global graph theoretical measures. In male fXPCs, global efficiency was significantly negatively associated with the number of CGG repeats. For nodal measures, significant group differences were found between male fXPCs and male HCs in the right fusiform and the right ventral diencephalon, and in the left hippocampus [for nodal clustering coefficient ]. In female fXPCs, CC in the left superior parietal cortex correlated with counting performance in an enumeration task. © 2014 Wiley Periodicals, Inc.