Benjamin Campbell

Middle childhood, the period from 6 to 12 years of age, is defined socially by increasing autonomy and emotional regulation, somatically by the development of anatomical structures for subsistence, and endocrinologically by adrenarche, the adrenal production of dehydroepiandrosterone (DHEA). Here I suggest that DHEA plays a key role in the coordinated development of the brain and body beginning with middle childhood, via energetic allocation. I argue that with adrenarche, increasing levels of circulating DHEA act to down-regulate the release of glucose into circulation and hence limit the supply of glucose which is needed by the brain for synaptogenesis. Furthermore, I suggest the antioxidant properties of DHEA may be important in maintaining synaptic plasticity throughout middle childhood within slow-developing areas of the cortex, including the insula, thamalus, and anterior cingulate cortex. In addition, DHEA may play a role in the development of body odor as a reliable social signal of behavioral changes associated with middle childhood.

Disordered wrongdoing describes wrongdoing which is causally connected to a wrongdoer’s mental disorder. A common attitude toward disordered wrongdoing is that the disorder is an “explanation” but not an “excuse” for the wrongdoing. Mental disorders, though, are often thought to be conditions that limit one’s freedom to choose alternative courses of action. These sorts of constraints on freedom are taken in ethical philosophy and democratic judicial systems to strongly reduce one's moral responsibility for a wrong act, if not remove it altogether in many cases. Rather than focusing on this legal interpretation of responsibility, I will focus on the “holistic” ethical context of how we treat disordered wrongdoers: our ethical comportment. I argue that our basic attitude toward disordered wrongdoers, on account of these constraints in freedom, should be compassionate. I explicitly focus on the meaning of compassion as it relates to a moral obligation to be understanding toward the reasons disordered wrongdoers have for their actions. We close out by giving a formal statement of our thesis, as well as a summary of what we have concluded throughout the paper.