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47Incorporating Global Components into Ethics EducationScience and Engineering Ethics 19 (1): 287-298. 2013.Ethics is central to science and engineering. Young engineers need to be grounded in how corporate social responsibility principles can be applied to engineering organizations to better serve the broader community. This is crucial in times of climate change and ecological challenges where the vulnerable can be impacted by engineering activities. Taking a global perspective in ethics education will help ensure that scientists and engineers can make a more substantial contribution to development t…Read more
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10Plant biomass is a large source of fermentable sugars for the synthesis of bioproducts using engineered microbes. These sugars are stored as cell wall polymers, mainly cellulose and hemicellulose, and are embedded with lignin, which makes their enzymatic hydrolysis challenging. One of the strategies to reduce cell wall recalcitrance is the modification of lignin content and composition. Lignin is a phenolic polymer of methylated aromatic alcohols and its synthesis in tissues developing secondary…Read more
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8The cyclooxygenase 2 pathway has been implicated in the molecular pathogenesis of many malignancies, including lung cancer. Apricoxib, a selective COX-2 inhibitor, has been described to inhibit epithelial-mesenchymal transition in human malignancies. The mechanism by which apricoxib may alter the tumor microenvironment by affecting EMT through other important signaling pathways is poorly defined. IL-27 has been shown to have anti-tumor activity and our recent study showed that IL-27 inhibited EM…Read more
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6© 2016 The Authors The Plant Journal © 2016 John Wiley & Sons LtdSphingolipids are a major component of plant plasma membranes and endomembranes, and mediate a diverse range of biological processes. Study of the highly glycosylated glycosyl inositol phosphorylceramide sphingolipids has been slow as a result of challenges associated with the extractability of GIPCs, and their functions in the plant remain poorly characterized. We recently discovered an Arabidopsis GIPC glucuronosyltransferase, IN…Read more
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6Lithium-oxygen cells are a promising power source, and carbons are an attractive non-metal catalyst for air electrodes. To improve the electrochemical performance, various carbons are heated in an inert atmosphere. It is found that heat treatment at 900 C can differently improve the electrochemical performance of multiwalled carbon nanotubes, acetylene carbon black and activated carbon, but the improvement of CNTs is the most obvious. After heat treatment, the peak current density of the oxygen …Read more
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5© The Author 2016. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists.Lignin poses a major challenge in the processing of plant biomass for agro-industrial applications. For bioengineering purposes, there is a pressing interest in identifying and characterizing the enzymes responsible for the biosynthesis of lignin. Hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyl transferase is a key metabolic entry point for the synthesis of the most important lignin monom…Read more
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5© 2016 The Author.Background: BAHD acyltransferases, named after the first four biochemically characterized enzymes of the group, are plant-specific enzymes that catalyze the transfer of coenzyme A-activated donors onto various acceptor molecules. They are responsible for the synthesis in plants of a myriad of secondary metabolites, some of which are beneficial for humans either as therapeutics or as specialty chemicals such as flavors and fragrances. The production of pharmaceutical, nutraceuti…Read more
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3Monoterpenes are the main components of essential oils and are possible precursors for many commodity chemicals and high energy density fuels. Monoterpenes are synthesized from geranyl diphosphate, which is also the precursor for the biosynthesis of farnesyl diphosphate. FPP biosynthesis diverts the carbon flux from monoterpene production to C15 products and quinone biosynthesis. In this study, we tested a chromosomal mutation of E. coli's native FPP synthase to improve GPP availability for the …Read more
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Ethics for Construction Engineers and Managers in a Globalized MarketIn C. Murphy, P. Gardoni, H. Bashir, C. E. Harris Jr & E. Masad (eds.), Engineering Ethics for a Globalized World, Springer International Publishing. 2015.Ethical decision-making is central to the practice of construction engineering and management. This is no more evident than in the twenty-first century, when the construction industry must function in very diverse organizational contexts. Whilst construction companies pursue projects in international markets, many investors are buying or forming joint ventures with domestic companies. New and varied professional attitudes have recently arrived in western markets such as the United States and Aus…Read more
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University of Wisconsin-La CrosseRegular Faculty
La Crosse, Wisconsin, United States of America