Guodong Zhang

© 2015 Thessen et al.Understanding the interplay between environmental conditions and phenotypes is a fundamental goal of biology. Unfortunately, data that include observations on phenotype and environment are highly heterogeneous and thus difficult to find and integrate. One approach that is likely to improve the status quo involves the use of ontologies to standardize and link data about phenotypes and environments. Specifying and linking data through ontologies will allow researchers to increase the scope and flexibility of large-scale analyses aided by modern computing methods. Investments in this area would advance diverse fields such as ecology, phylogenetics, and conservation biology. While several biological ontologies are well-developed, using them to link phenotypes and environments is rare because of gaps in ontological coverage and limits to interoperability among ontologies and disciplines. In this manuscript, we present use cases from diverse disciplines to illustrate questions that could be answered more efficiently using a robust linkage between phenotypes and environments, two proof-of-concept analyses that show the value of linking phenotypes to environments in fishes and amphibians, and two proposed example data models for linking phenotypes and environments using the extensible observation ontology and the Biological Collections Ontology ; these provide a starting point for the development of a data model linking phenotypes and environments.

Strauss’s analysis of Machiavelli is both about his argument and action. He looks Machiavelli’s argument through the lens of classicalpolitical philosophy especially Plato’s political philosophy. He believed Machiavelli had not achieved important theoretical innovation. He looks Machiavelli’s action through the lens of modernity. He believed Machiavelli’s political thought did not perform a good function as it did in the last several centuries any more. Moreover, Strauss supplement Machiavelli’s political thought with a discussion of the problem of technique. Strauss’s caution of the technical innovation makes sense, but his distinction between theoretical science and technique is not convincing.

Montesquieu believes that human beings have three kinds of natures: self-preserving, imperfect knowledge and passions. The first and the third nature tend to conflict with each other, and the result is the state of war, in which human natures could not be satisfied. Montesquieu uses this theory of human nature to judge all the kinds of governments, and finds that the virtuous republic, despotism and monarchy all have important defects. Especially, the monarchy by nature tends to degenerate into despotism, which is a realistic threat to him and his contemporaries. To solve this political problem, Montesquieu himself develops a two-fold solution: he wants to establish a certain kind of positive laws to satisfy the first nature, and wants to promote commerce to satisfy the third nature. Moreover, his ideal-government has important differences with the English political system.