• PhilPapers
  • PhilPeople
  • PhilArchive
  • PhilEvents
  • PhilJobs
  • Sign in
PhilPeople
 
  • Sign in
  • News Feed
  • Find Philosophers
  • Departments
  • Radar
  • Help
 
profile-cover
Drag to reposition
profile picture

J. L. Bryant

Western Washington University
  •  Home
  •  Publications
    10
    • Most Recent
    • Most Downloaded
    • Topics
  •  News and Updates
    1

 More details
  • Western Washington University
    Department of Philosophy
    Undergraduate
Bellingham, Washington, United States of America
  • All publications (10)
  •  5
    Deleuze/derrida: The politics of territoriality
    with J. Cash, J. Hewitt, L. W., D. Petherbridge, J. Rundell, G. Schwab, and J. Smith
    Critical Horizons 4 (2): 147-156. 2003.
    Gilles DeleuzeDerrida: Social and Political PhilosophyDerrida and Other PhilosophersPolitical Theory
  •  65
    Wnt signalosomes: What we know that we do not know
    with Heather Hartmann, Ghalia Saad Siddiqui, David J. Robbins, Vivian L. Weiss, Yashi Ahmed, and Ethan Lee
    Bioessays 47 (2): 2400110. 2025.
    Signaling through the Wnt/β‐catenin pathway is relayed through three multiprotein complexes: (1) the membrane‐associated signalosome, which includes the activated Wnt receptors, (2) the cytoplasmic destruction complex that regulates turnover of the transcriptional coactivator β‐catenin, and (3) the nuclear enhanceosome that mediates pathway‐specific transcription. Recent discoveries have revealed that Wnt receptor activities are tightly regulated to maintain proper tissue homeostasis and that ab…Read more
    Signaling through the Wnt/β‐catenin pathway is relayed through three multiprotein complexes: (1) the membrane‐associated signalosome, which includes the activated Wnt receptors, (2) the cytoplasmic destruction complex that regulates turnover of the transcriptional coactivator β‐catenin, and (3) the nuclear enhanceosome that mediates pathway‐specific transcription. Recent discoveries have revealed that Wnt receptor activities are tightly regulated to maintain proper tissue homeostasis and that aberrant receptor upregulation enhances Wnt signaling to drive tumorigenesis, highlighting the importance of signalosome control. These studies have focused on the detailed process by which Wnt ligands engage their coreceptors, LRP5/6 and Frizzled. However, the components that constitute the signalosome and the regulation of their assembly remain undefined. In this review, we discuss Wnt/β‐catenin signalosome composition and the mechanisms that regulate signalosome assembly, including the role of biomolecular condensates and ubiquitylation. We also summarize the evidence for the presence of Wnt ligand‐independent signalosome formation.
    Natural Sciences
  •  3
    Issues and debates in contemporary social and critical philosophy
    with John Rundell, Danielle Petherbridge, John Hewitt, and Jeremy Smith
    Philosophy of Social Science, General Works
  •  30
    Artmaking in the age of global capitalism: visual practices, philosophy, politics
    Edinburgh University Press. 2019.
    Jan Bryant looks at the strategies visual artists and filmmakers are using to criticise the social and economic conditions shaping our historical moment. She then assesses how the world is being positively re-imagined through their work today.
    Aesthetics
  •  95
    Issues and debates in contemporary critical and social philosophy
    with John Rundell, Danielle Petherbridge, John Hewitt, and Jeremy Smith
    Critical Horizons 5 (1): 1-25. 2004.
    Continental Political Philosophy
  •  80
    Transcutaneous Vagus Nerve Stimulation Enhances Response Selection During Sequential Action
    with Maarten A. Immink, Alessandra Finisguerra, and Lorenza S. Colzato
    Frontiers in Psychology 9. 2018.
    Philosophy of Cognitive Science
  •  96
    Deleuze/derrida: The Politics of Territoriality
    with John Cash, John Hewitt, Wei Kwok, Danielle Petherbridge, John Rundell, Gabriele Schwab, and Jeremy Smith
    Critical Horizons 4 (2): 147-156. 2003.
    Gilles Deleuze
  •  112
    Contingency, Fragility, Difference
    with John Cash, John Hewitt, Wei Kwok, Danielle Petherbridge, John Rundell, and Jeremy Smith
    Critical Horizons 4 (1): 1-5. 2003.
  •  116
    Others as strangers
    with John Cash, John Hewitt, Danielle Petherbridge, and John Rundell
    Critical Horizons 3 (1): 1-5. 2002.
    PoststructuralismContinental Political PhilosophyCultural Relativism
  •  91
    Modernities, civilisations, natures
    with John Cash, John Hewitt, Danielle Petherbridge, and John Rundell
    Critical Horizons 3 (2): 159-163. 2002.
PhilPeople logo

On this site

  • Find a philosopher
  • Find a department
  • The Radar
  • Index of professional philosophers
  • Index of departments
  • Help
  • Acknowledgments
  • Careers
  • Contact us
  • Terms and conditions

Brought to you by

  • The PhilPapers Foundation
  • The American Philosophical Association
  • Centre for Digital Philosophy, Western University
PhilPeople is currently in Beta Sponsored by the PhilPapers Foundation and the American Philosophical Association
Feedback