•  67
    Artifact characterization and mitigation techniques during concurrent sensing and stimulation using bidirectional deep brain stimulation platforms
    with Michaela E. Alarie, Nicole R. Provenza, Michelle Avendano-Ortega, Sarah A. McKay, Ayan S. Waite, Raissa K. Mathura, Sameer A. Sheth, David A. Borton, and Wayne K. Goodman
    Frontiers in Human Neuroscience 16 1016379. 2022.
    Bidirectional deep brain stimulation (DBS) platforms have enabled a surge in hours of recordings in naturalistic environments, allowing further insight into neurological and psychiatric disease states. However, high amplitude, high frequency stimulation generates artifacts that contaminate neural signals and hinder our ability to interpret the data. This is especially true in psychiatric disorders, for which high amplitude stimulation is commonly applied to deep brain structures where the native…Read more
  •  15
    Intraoperative Characterization of Subthalamic Nucleus-to-Cortex Evoked Potentials in Parkinson’s Disease Deep Brain Stimulation
    with Lila H. Levinson, David J. Caldwell, Jeneva A. Cronin, Brady Houston, Steve I. Perlmutter, Kurt E. Weaver, Jeffrey G. Ojemann, and Andrew L. Ko
    Frontiers in Human Neuroscience 15. 2021.
    Deep brain stimulation of the subthalamic nucleus is a clinically effective tool for treating medically refractory Parkinson’s disease, but its neural mechanisms remain debated. Previous work has demonstrated that STN DBS results in evoked potentials in the primary motor cortex, suggesting that modulation of cortical physiology may be involved in its therapeutic effects. Due to technical challenges presented by high-amplitude DBS artifacts, these EPs are often measured in response to low-frequen…Read more
  •  13
    A Pilot Study on Data-Driven Adaptive Deep Brain Stimulation in Chronically Implanted Essential Tremor Patients
    with Sebastián Castaño-Candamil, Benjamin I. Ferleger, Andrew Haddock, Sarah S. Cooper, Andrew Ko, Howard J. Chizeck, and Michael Tangermann
    Frontiers in Human Neuroscience 14. 2020.