Jing Zhou

Background and purposeThis study aimed to analyze the feasibility and safety of endovascular therapy (EVT) in patients with acute posterior circulation stroke and vertebrobasilar dolichoectasia (VBD).Materials and methodsBASILAR was a national prospective registry of consecutive patients with symptomatic and imaging-confirmed acute stroke in the posterior circulation within 24 h of symptom onset. We evaluated EVT feasibility and safety in patients with VBD. Primary outcomes included improvement in modified Rankin Scale scores (mRS) at 90 days and mortality within 90 days. The secondary outcome was the rate of favorable functional outcome, defined as mRS ≤ 3 (indicating independent ambulation) at 90 days. Safety outcomes included surgery-related complications and other serious adverse events.ResultsA total of 534 cases were included: 159 with VBD and 375 controls. No significant difference in mRS at 90 days was found between groups, but patients with VBD had a higher baseline National Institutes of Health Stroke Scale (NIHSS) score [30 (19–33) vs. 25 (15–32)] and were older [65 (59–74) vs. 63 (55–72) year]. After propensity score matching, there were no significant differences in baseline NIHSS score between the two groups, and the efficacy and safety of EVT were similar between patients with or without VBD. Furthermore, the prognostic effect of puncture-to-recanalization time on the probability of mortality within 90 days in EVT-treated patients with VBD was significant {adjusted odds ratio, 1.008 [95% confidence interval (1.001–1.015)]}.ConclusionEndovascular therapy is safe and feasible in patients with acute posterior circulation stroke and VBD. The puncture-to-recanalization time is important for predicting the prognosis of EVT-treated patients with VBD.

The fundamental aim of epistemology and moral philosophy is the pursuit of foundational principles. Pragmatism resolves the so-called "fact-value dichotomy" by showing how values emerge dynamically through practice, thus establishing a mutually constitutive relationship between knowledge and ethics. Charles S. Peirce's semiotics implicitly outlines an unfinished ethical project: semiotic ethics. When we think with signs that are triadically structured as representamen, object, and interpretant rather than think with concepts that are dyadically structured as meaning and reference, we will have the opportunity to transcend all traditional forms of dualism. Semiosis simultaneously configures the cognitive "I-World" relations and the ethical "I-We" relations, thereby enacting the dual grounding of epistemology and moral philosophy. A critical engagement with Karl-Otto Apel's transcendental interpretation of Peircean semiotics reveals that such dual grounding can be realized through the dynamic, evolving practices of communities, resulting in a grounding without a metaphysical Ground for epistemology and ethics. The triadic nature of signs, the normative dimensions of communal practices, and an orientation toward future-directed immanent transcendence collectively underpin this dual grounding task, illuminating the interdependence of ethical norms and epistemic construction.

This article explores the construction of subjectivity in Internet-based Chinese fantasy novels and their connection to the spirit of enlightenment and posthumanism. These novels re-examine the validity of scientific civilization and enlightenment reason, deconstructing and rewriting grand narratives through individualism in the pre-modern magical world. Moreover, this literary genre, rooted in a posthumanist perspective, challenges traditional concepts of the body with technologies that enhance strength and offer immortality. Chinese fantasy novels open up a path for the decentralized, anti-anthropocentric revolution of subjectivity, leading toward a world that fully activates material vitality and embraces equality among all beings.

The role of Charles Peirce as the father of pragmatism has long been misunderstood, even though he revised and restated his position several times. In his first exposition of pragmatism in 1877-1878, he emphasized that pragmatism was a method of understanding the meaning of concepts based on practical effects. This exposition had some traces of psychologism, which led to common misunderstandings. In sporadic revisions between 1891 and 1902, Peirce rejected the idea of understanding the meaning of concepts based on individual actions and mental feelings and instead emphasized the importance of understanding the general meaning of concepts through communal inquiry. In his third exposition in 1903, he emphasized that pragmatism was a logical method based on normative sciences and equated it with abduction. In his fourth and final exposition between 1905 and 1907, he analyzed general phenomena based on semiosis and focused on understanding the meaning of signs rather than concepts that presuppose the action of signs. By analyzing these four expositions, it can be seen that Peircean pragmatism has anti-psychological features and emphasizes the scientific exploration of the community to analyze universal phenomena, making it a more scientific pragmatism.

In advocating gender equality today, we should not only pay attention to women's social status but also call for the women's psychological identification of class equality. What dominates female class identification? To answer this question, based on the data of the Chinese General Social Survey in 2015, this study constructs a female class identity framework from five aspects: the mother's intergenerational influence, female personal characteristics, lifestyle, gender consciousness, and spouse status. In this study, the ordered logit model is used to empirically analyze the impact of various factors on female class identification, and the results show the following: gender consciousness has a significant impact on female class identification. Lifestyle has a significant impact on the situation of having a spouse. Spouse status has a significant positive effect on female class identification. But the mother's intergenerational influence has no effect on female class identification. Therefore, this paper suggests that we should improve laws and regulations to protect women's normal rights, encourage women to establish an independent and self-improvement character, and enhance the class consciousness of women, especially rural women, in order to achieve the overall improvement of female class and psychological identification.

The purpose of this study was to examine how culture shapes creativity by reviewing empirical findings across diverse studies. The impact of culture on creativity is typically manifested in three ways: (a) people from different cultures or settings have distinct implicit and/or explicit conceptions of creativity; (b) individuals from different cultures, particularly those from individualist and collectivist cultures, show differences in preferred creative processes and creative processing modes (e.g., usefulness seems more important than novelty in the East, whereas novelty seems equally important as usefulness, if not more so, in the West) when they are engaged in creative endeavors; (c) creativity may be assessed using different measures based on culture-related contents or materials, and findings are accurate only when culturally appropriate or culturally fair measures are used. Potential implications and future directions are also proposed.

This study explored the association between out-of-school physical activity and mathematical achievement in relation to mathematical anxiety, as well as the influence of parents’ support for their children’s physical activity on this association, to examine whether parental support for physical activity affects mental health and academic performance. Data were collected from the responses of 22,509 children in Grade 4 from six provinces across eastern, central, and western China who completed the mathematics component and the physical education and health component of the national-level education quality assessment. A moderated moderated-mediation model was tested using PROCESS v3.4 and SPSS v19.0, with socioeconomic status, school location, and body mass index as controlled variables. Out-of-school physical activity had a positive effect on children’s mathematical achievement, and math anxiety partially mediated this association. The indices of conditional moderated mediation through the parental support of both girls and boys were, respectively, significant, indicating that children can benefit from physical activity, and that increased perceived parental support for physical activity can alleviate their children’s math anxiety and improve their mathematics, regardless of gender. However, gender differences were observed in the influence of parental support for physical activity on anxiety: Although girls’ math anxiety levels were significantly higher, the anxiety levels of girls with high parental support were significantly lower than those of boys with low parental support.

This study investigated the association between syntactic awareness and L2 Chinese passage-level reading comprehension among 209 Chinese as a second language adult-learners. The participants were administered a character knowledge test, a vocabulary knowledge test, a morphological awareness test, a grammatical judgment and correction test, a word order test, and two reading comprehension tests. Partial correlation analyses showed that the participants’ performance in two syntactic awareness tasks were significantly positively correlated with their passage-level reading comprehension. Multiple regression analyses revealed that syntactic awareness made a unique contribution to L2 Chinese reading even when the effects of age, major, gender, length of learning Chinese, character knowledge, vocabulary knowledge, and morphological awareness were controlled for. In addition, the word order knowledge had a stronger predicting power to L2 Chinese reading comprehension compared to the grammatical judgment/correction ability.

AbstractIn marketing channels, distributor whistleblowing can deter unethical behaviors, though little academic research investigates this tactic. Drawing on whistleblowing literature in business ethics and organizational theory, as well as field interviews with channel managers, this article identifies and elucidates the notion of distributor whistleblowing in marketing channels. Specifically, this study investigates how a manufacturer’s control modes (monitoring and incentives) encourage or discourage distributor whistleblowing. This study also considers the impact of distributor whistleblowing on relationship quality and the moderating effects of exchange hazards (i.e., transaction-specific investments and market uncertainty). The empirical results from a sample of 211 Chinese distributors indicate that manufacturers’ monitoring inhibits, whereas incentives boost distributor whistleblowing. Further, a positive link arises between distributor whistleblowing and relationship quality, which is weakened by distributor transaction-specific investments and strengthened by market uncertainty.

This article by the Theatre Arts analysis of Brecht's vision to theater theory, arrive at different results of previous studies to determine its important contribution to the "Watch Art", which not only marked the beginning of art theory who is also its theory and practice in the primary. Actors to observe, model and critical role to replace the traditional Aristotelian theater actor in the role of being the embodiment, manufacturing the atmosphere, causing the audience's melodramatic, but into the illusion of state. This innovative art of the actor with the echoes of the "watch art", the audience in the theater to develop observation and critical attitude, will produce the overall communication within the theater, take the theater, the audience not only as a reform of the social attitude, and can be maintenance of national social security. I would like to analyze Brecht's theory of theater in light of the science of theater arts . New findings confirm Brecht's most important contribution to theater has been "Zuschaukunst" . This is not only a theory on the origin of art, but also includes the basis of his theory and practice. Role observations, demonstration and critiques of actors replace the traditional Aristotelian theory of theater. In this way, the audience can identify with the actor's roles and fall into a state of illusion . This revolutionary theatrical experience is thus termed "Zuschaukunst". An intra-theatrical transaction emerges when an audience starts to observe and criticize. This attitude helps the audience reform society and preserve national security

The external surfaces of the human body, as well as its internal organs, constantly experience different kinds of mechanical stimulations. For example, tubular epithelial cells of the kidney are continuously exposed to a variety of mechanical forces, such as fluid flow shear stress within the lumen of th nephron. The majority of epithelial cells along the nephron, except intercalated cells, possess a primary cilium, an organelle projecting from the cell's apical surface into the luminal space. Despite its discovery over 100 years ago, the primary cilium's function continued to elude researchers for many decades. However, recent studies indicate that renal cilia have a sensory function. Studies on polycystic kidney disease (PKD) have identified many of the molecular players, which should help solve the mystery of how the renal cilium senses fluid flow. In this review, we will summarize the recent breakthroughs in PKD research and discuss the role(s) of th polycystin signaling complex in mediating mechanosensory function by the primary cilium of renal epithelium as well as of the embryonic node. BioEssays 26:844–856, 2004. © 2004 Wiley Periodicals, Inc.