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    An oncospace for human cancers
    with Guim Aguadé-Gorgorió and Ricard Solé
    Bioessays 45 (5): 2200215. 2023.
    Human cancers comprise an heterogeneous array of diseases with different progression patterns and responses to therapy. However, they all develop within a host context that constrains their natural history. Since it occurs across the diversity of organisms, one can conjecture that there is order in the cancer multiverse. Is there a way to capture the broad range of tumor types within a space of the possible? Here we define the oncospace, a coordinate system that integrates the ecological, evolut…Read more