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    The Toxoplasma dense granule proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole (review)
    with Daniel A. Gold, Aaron D. Kaplan, Agnieszka Lis, Glenna C. L. Bett, Emily E. Rosowski, Kimberly M. Cirelli, Alexandre Bougdour, Saima M. Sidik, Sebastian Lourido, Pascal F. Egea, Peter J. Bradley, Mohamed-Ali Hakimi, Randall L. Rasmusson, and Jeroen P. J. Saeij
    © 2015 Elsevier Inc.Toxoplasma gondii is a protozoan pathogen in the phylum Apicomplexa that resides within an intracellular parasitophorous vacuole that is selectively permeable to small molecules through unidentified mechanisms. We have identified GRA17 as a Toxoplasma-secreted protein that localizes to the parasitophorous vacuole membrane and mediates passive transport of small molecules across the PVM. GRA17 is related to the putative Plasmodium translocon protein EXP2 and conserved across P…Read more